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Cancer Immunology, Immunotherapy

Issue 7/2015

Content (13 Articles)

Original Article

Two distinct effector memory cell populations of WT1 (Wilms’ tumor gene 1)-specific cytotoxic T lymphocytes in acute myeloid leukemia patients

Yoshiki Nakae, Yoshihiro Oka, Fumihiro Fujiki, Soyoko Morimoto, Toshio Kamiya, Satoshi Takashima, Jun Nakata, Sumiyuki Nishida, Hiroko Nakajima, Naoki Hosen, Akihiro Tsuboi, Taiichi Kyo, Yusuke Oji, Kenji Mizuguchi, Atsushi Kumanogoh, Haruo Sugiyama

Original Article

Adoptive T cell therapy combined with intralesional administrations of TG1042 (adenovirus expressing interferon-γ) in metastatic melanoma patients

Amir Khammari, Jean-Michel Nguyen, Melanie Saint-Jean, Anne-Chantal Knol, Marie-Christine Pandolfino, Gaelle Quereux, Anabelle Brocard, Lucie Peuvrel, Soraya Saiagh, Vincent Bataille, Jean-Marc Limacher, Brigitte Dreno

Original Article

Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T

Rachel A. Burga, Mitchell Thorn, Gary R. Point, Prajna Guha, Cang T. Nguyen, Lauren A. Licata, Ronald P. DeMatteo, Alfred Ayala, N. Joseph Espat, Richard P. Junghans, Steven C. Katz

Original Article

Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions

Yannick Willemen, Johan M. J. Van den Bergh, Eva Lion, Sébastien Anguille, Vicky A. E. Roelandts, Heleen H. Van Acker, Steven D. I. Heynderickx, Barbara M. H. Stein, Marc Peeters, Carl G. Figdor, Viggo F. I. Van Tendeloo, I. Jolanda de Vries, Gosse J. Adema, Zwi N. Berneman, Evelien L. J. Smits

Original Article

Persistent HPV16/18 infection in Indian women with the A-allele (rs6457617) of HLA-DQB1 and T-allele (rs16944) of IL-1β −511 is associated with development of cervical carcinoma

Sankhadeep Dutta, Chandraditya Chakraborty, Ranajit Kumar Mandal, Partha Basu, Jaydip Biswas, Susanta Roychoudhury, Chinmay Kumar Panda

Open Access Original Article

Cytotoxic T lymphocyte antigen 4 expression in human breast cancer: implications for prognosis

Haiming Yu, Junlan Yang, Shunchang Jiao, Ying Li, Wei Zhang, Jiandong Wang

Original Article

Immunostimulatory early phenotype of tumor-associated macrophages does not predict tumor growth outcome in an HLA-DR mouse model of prostate cancer

Vladimir Riabov, David Kim, Surmeet Chhina, Richard B. Alexander, Elena N. Klyushnenkova

Focussed Research Review

Immune checkpoint combinations from mouse to man

Midan Ai, Michael A. Curran

Open Access Focussed Research Review

Orchestrating an immune response against cancer with engineered immune cells expressing αβTCRs, CARs, and innate immune receptors: an immunological and regulatory challenge

Moniek A. de Witte, Guido J. J. Kierkels, Trudy Straetemans, Cedrik M. Britten, Jürgen Kuball

Focussed Research Review

Adoptive immunotherapy of cancer utilizing genetically engineered lymphocytes

Hiroaki Ikeda, Hiroshi Shiku

Focussed Research Review

Intratumoral immunotherapy for melanoma

Manisha Singh, Willem W. Overwijk

Meeting Report

Cancer immunotherapy achieves breakthrough status: 12th annual meeting of the association for cancer immunotherapy (CIMT), Mainz, Germany, May 6–8, 2014

Björn-Philipp Kloke, Andrea Mahr, Robert A. Jabulowsky, Sarah Kutscher, Richard Rae, Cedrik M. Britten

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine