Issue 6/2002
Content (12 Articles)
In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines
Ioannis A. Avramis, Garyfallia Christodoulopoulos, Atsushi Suzuki, Walter E. Laug, Ignacio Gonzalez-Gomez, George McNamara, Edward A. Sausville, Vassilios I. Avramis
Clinical pharmacokinetics, pharmacodynamics and metabolism of the novel matrix metalloproteinase inhibitor ABT-518
Mirjam Crul, Laurens V. Beerepoot, Ellen Stokvis, Johannes S. Vermaat, Hilde Rosing, Jos H. Beijnen, Emile E. Voest, Jan H. Schellens
Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule
Nadja E. Schoemaker, Ron A. Mathôt, Patrick Schöffski, Hilde Rosing, Jan H. Schellens, Jos H. Beijnen
Decreased tumor blood flow as measured by positron emission tomography in cancer patients treated with interleukin-1 and carboplatin on a phase I trial
Theodore F. Logan, Fayega Jadali, Merrill J. Egorin, Mark Mintun, Donald Sashin, William E. Gooding, Yong Choi, Harry Bishop, Donald L. Trump, Diane Gardner, John Kirkwood, Daniel Vlock, Candace Johnson
The raltitrexed-vinorelbine combination: a phase I pharmacokinetic and pharmacodynamic trial in advanced breast cancer
Jean-Marc Ferrero, Emmanuel Chamorey, Nicolas Magné, Frédéric Leccia, Rémy Largillier, Moïse Namer, Gérard Milano
Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice
Maria V. Papadopoulou, Ming Ji, Xinhai Ji, William D. Bloomer, Melinda G. Hollingshead
Phase I clinical and pharmacokinetic trial of the cyclin-dependent kinase inhibitor flavopiridol
James P. Thomas, Kendra D. Tutsch, James F. Cleary, Howard H. Bailey, Rhoda Arzoomanian, Dona Alberti, Kris Simon, Chris Feierabend, Kimberly Binger, Rebecca Marnocha, Amy Dresen, George Wilding
Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver
Shogo Ozawa, Masashi Hamada, Norie Murayama, Yukiko Nakajima, Nahoko Kaniwa, Yoshiaki Matsumoto, Masamichi Fukuoka, Jun-ichi Sawada, Yasuo Ohno
Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts
Henriette Gourdeau, Philippe Genne, Salam Kadhim, Lucie Bibeau, Olivier Duchamp, France Ouellet, Jean-Marc deMuys, David Y. Bouffard, Giorgio Attardo
Dosing sequence-dependent pharmacokinetic interaction of oxaliplatin with paclitaxel in the rat
Jing Liu, Eric H. Kraut, Stanley Balcerzak, Michael Grever, Steven D'Ambrosio, Kenneth K. Chan
The doxorubicin-cardioprotective drug dexrazoxane undergoes metabolism in the rat to its metal ion-chelating form ADR-925
Patricia E. Schroeder, Brian B. Hasinoff
Mylotarg combined with topotecan and cytarabine in patients with refractory acute myelogenous leukemia
Jorge Cortes, Apostolia M. Tsimberidou, Ricardo Alvarez, Deborah Thomas, Miloslav Beran, Hagop Kantarjian, Elihu Estey, Francis J. Giles