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Cancer Chemotherapy and Pharmacology

Issue 5/2002

Content (12 Articles)

Original Article

Phase I pharmacodynamic study of time and sequence dependency of hydroxyurea in combination with gemcitabine: a California Cancer Consortium Trial

Yun Yen, Warren Chow, Lucille Leong, Kim Margolin, Robert Morgan, James Raschko, Stephen Shibata, George Somlo, Przemyslaw Twardowski, Paul Frankel, Jeff Longmate, Timothy Synold, Edward M. Newman, Heinz-Josef Lenz, David Gandara, James H. Doroshow

Original Article

Tumour cell uptake of the metastasis inhibitor ruthenium complex NAMI-A and its in vitro effects on KB cells

Fabiana Frausin, Moreno Cocchietto, Alberta Bergamo, Vito Scarcia, Ariella Furlani, Gianni Sava

Original Article

Pharmacokinetics and organ distribution of N-methanocarbathymidine, a novel thymidine analog, in mice bearing tumors transduced with the herpes simplex thymidine kinase gene

Roy Noy, Zvi Ben-Zvi, Miri Elezra, Fabio Candotti, Harry Ford, John C. Morris, Victor E. Marquez, David G. Johns, Riad Agbaria

Original Article

High-dose, single-agent irinotecan as first-line therapy in the treatment of metastatic colorectal cancer

M. Ychou, J. Raoul, F. Desseigne, C. Borel, F. Caroli-Bosc, J. Jacob, J. Seitz, A. Kramar, A. Hua, P. Lefebvre, C. Couteau, Y. Merrouche

Original Article

Establishment and characterization of a mouse FM3A cell mutant resistant to topoisomerase II-inhibitor NC-190

Kazunori Samata, Takehiro Yamagishi, Tomoko Ichihara, Kayoko Nanaumi, Tomotake Ikeda, Hisao Ikeya, Aiko Kuraishi, Shiro Nakaike, Keiko Kashiwagi, Kazuei Igarashi

Original Article

Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model

Michael Guarnieri, Ann Biser-Rohrbaugh, Betty M. Tyler, Patrik Gabikian, Tracie E. Bunton, Qing Wu, Jon Weingart, Benjamin S. Carson

Original article

A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia

John Panetta, Yuri Yanishevski, Ching-Hon Pui, John T. Sandlund, Jeffrey Rubnitz, Gaston K. Rivera, Raul Ribeiro, William E. Evans, Mary V. Relling

Original Article

Angiostatin potentiates cyclophosphamide treatment of metastatic disease

Helena J. Mauceri, Saraswathy Seetharam, Michael A. Beckett, Philip L. Schumm, Ann Koons, Vinay K. Gupta, James O. Park, Abdullah Manan, John Y. Lee, Anthony G. Montag, Donald W. Kufe, Ralph R. Weichselbaum

Short Communication

Carboplatin hypersensitivity presenting as coronary vasospasm – a case report

Martin R. Chasen, Iftikar O. Ebrahim

Review

Current status of the molecular mechanisms of anticancer drug-induced apoptosis

Ryungsa Kim, Kazuaki Tanabe, Yoko Uchida, Manabu Emi, Hideki Inoue, Tetsuya Toge

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
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