Issue 4/2006
Content (16 Articles)
Population pharmacokinetic analysis of ten phase II clinical trials of pemetrexed in cancer patients
Jane E Latz, Ajai Chaudhary, Atalanta Ghosh, Robert D Johnson
A semimechanistic-physiologic population pharmacokinetic/pharmacodynamic model for neutropenia following pemetrexed therapy
Jane E Latz, Mats O Karlsson, James J Rusthoven, Atalanta Ghosh, Robert D Johnson
Clinical application of a semimechanistic-physiologic population PK/PD model for neutropenia following pemetrexed therapy
Jane E. Latz, James J. Rusthoven, Mats O. Karlsson, Atalanta Ghosh, Robert D. Johnson
Phase II study with a combination of epirubicin, cisplatin, UFT, and leucovorin in advanced hepatocellular carcinoma
Seok Jin Kim, Hee Yun Seo, Jong Gwon Choi, Hye Ryoung Sul, Hwa Jung Sung, Kyong Hwa Park, In Keun Choi, Sang Cheul Oh, So Young Yoon, Jae Hong Seo, Chul Won Choi, Byung Soo Kim, Sang Won Shin, Yeul Hong Kim, Jun Suk Kim
Interpreting cell cycle effects of drugs: the case of melphalan
Monica Lupi, Paolo Cappella, Giada Matera, Claudia Natoli, Paolo Ubezio
A liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of actinomycin-D and vincristine in children with cancer
Jeffrey M. Skolnik, Jeffrey S. Barrett, Heng Shi, Peter C. Adamson
Phase I and pharmacokinetic study of the novel redox-active agent, motexafin gadolinium, with concurrent radiation therapy in patients with locally advanced pancreatic or biliary cancers
Ramesh K. Ramanathan, Marwan Fakih, Sridhar Mani, Melvin Deutsch, Raymond P. Perez, Mark A. Ritter, Julie L. Eiseman, S. Percy Ivy, Donald L. Trump, Chandra P. Belani, Robert A. Parise, Douglas M. Potter, Merrill J. Egorin
Development and validation of limited sampling models for topotecan lactone pharmacokinetic studies in children
P. Kellie Turner, Lisa C. Iacono, John C. Panetta, Victor M. Santana, Najat C. Daw, Amar Gajjar, Clinton F. Stewart
Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro
Jocelyn L Carr, Malcolm D Tingle, Mark J McKeage
Characterizations of irofulven cytotoxicity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells
Maria Serova, Fabien Calvo, François Lokiec, Florence Koeppel, Virginie Poindessous, Annette K. Larsen, Emily S. Van. Laar, Stephen J. Waters, Esteban Cvitkovic, Eric Raymond
Pharmacokinetics and phototoxicity of purpurin-18 in human colon carcinoma cells using liposomes as delivery vehicles
Sulbha Sharma, Alok Dube, Biplab Bose, Pradeep K Gupta
Apoptosis induced by glycoprotein (150-kDa) isolated from Solanum nigrum L. is not related to intracellular reactive oxygen species (ROS) in HCT-116 cells
Sei-Jung Lee, Kye-Taek Lim
Effect of amifostine on the cytotoxicity of daunorubicin and daunoxome in tumor and normal cells
Michelutti Angela, Stocchi Raffaella, Candoni Anna, Tiribelli Mario, Calistri Elisabetta, Russo Domenico, Fanin Renato, Damiani Daniela
Antiproliferation and radiosensitization of caffeic acid phenethyl ester on human medulloblastoma cells
Yi-Hsien Lin, Jen-Hwey Chiu, Wen-Ser Tseng, Tai-Tong Wong, Shih-Hwa Chiou, Sang-Hue Yen
A phase II, open-label study of gefitinib (IRESSA) in patients with locally advanced, metastatic, or relapsed renal-cell carcinoma
Monika Jermann, Rolf A Stahel, Marc Salzberg, Thomas Cerny, Markus Joerger, Silke Gillessen, Rudolf Morant, Fritz Egli, Kaspar Rhyner, Jean A Bauer, Miklos Pless
Minimal clinical benefit of single agent Orathecin (Rubitecan) in heavily pretreated metastatic breast cancer
Silwan Chedid, Edgardo Rivera, Debbie K. Frye, Nuhad Ibrahim, Francisco Esteva, Vicente Valero, Gabriel Hortobagyi, Karl L. Mettinger, Massimo Cristofanilli