Issue 4/1998
Content (13 Articles)
Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic leukemia receiving 6-thioguanine versus 6-mercaptopurine
Norbert Erb, Dörthe O. Harms, Gritta Janka-Schaub
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin
Theodor W. Schulte, Leonard M. Neckers
Determination of flavopiridol (L86 8275; NSC 649890) in human plasma by reversed-phase liquid chromatography with electrochemical detection
Sherman F. Stinson, Kimberly Hill, Timothy J. Siford, Lawrence R. Phillips, Tracy W. Daw
Inhibition of intestinal microflora β-glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats
Kiyoshi Takasuna, Takehiro Hagiwara, Masaaki Hirohashi, Michiyuki Kato, Mamoru Nomura, Eiichi Nagai, Tsuyoshi Yokoi, Tetsuya Kamataki
Prevention of apomorphine- or cisplatin-induced emesis in the dog by a combination of methylnaltrexone and morphine
Joseph F. Foss, Chun-Su Yuan, Michael F. Roizen, Leon I. Goldberg
Fluorescence methods to assess multidrug resistance in individual cells
Eric J. Nelson, Noah T. Zinkin, Patricia M. Hinkle
Pharmacokinetics, antifolate activity and tissue distribution of PT523 in SCC VII tumor-bearing mice
Joel E. Wright, Mario Pardo, Anatoly Tretyakov, Wendy L. Alperin, Dorothy Trites, Andre Rosowsky
Prediction of carboplatin clearance calculated by patient characteristics or 24-hour creatinine clearance: a comparison of the performance of three formulae
Hiroaki Okamoto, Akira Nagatomo, Hideo Kunitoh, Hiroshi Kunikane, Koshiro Watanabe
A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice
F. M. Sirotnak, J. I. DeGraw, W. T. Colwell, J. R. Piper
Quaternary ammonium analogs of ether lipids inhibit the activation of protein kinase C and the growth of human leukemia cell lines
Francesca Civoli, Larry W. Daniel
Sequence effect of irinotecan (CPT-11) and topoisomerase II inhibitors in vivo
Joseph Paul Eder, Victor Chan, Julia Wong, Yee W. Wong, Gulshan Ara, David Northey, Naiyer Rizvi, Beverly A. Teicher
Advanced colorectal cancer in the elderly: results of consecutive trials with 5-fluorouracil-based chemotherapy
Silvana Chiara, Maria Teresa Nobile, Maura Vincenti, Rita Lionetto, Alberto Gozza, Maria Cristina Barzacchi, Ornella Sanguineti, Lazzaro Repetto, Riccardo Rosso
Superiority of hepatic arterial infusion in preventing catabolism of 5-FU compared with portal vein infusion revealed by an in vivo 19F NMR study
Kiyotaka Okuno, Norihiko Hirai, Yung Sun Lee, Dino Tarabar, Hideo Ueno, Masayuki Yasutomi