Issue 2/2008
Content (19 Articles)
Dose scheduling of the dual VEGFR and EGFR tyrosine kinase inhibitor vandetanib (ZD6474, Zactima®) in combination with radiotherapy in EGFR-positive and EGFR-null human head and neck tumor xenografts
Daniel L. Gustafson, Barbara Frederick, Andrea L. Merz, David Raben
Cell death in response to antimetabolites directed at thymidylate synthase
Karen W. Barbour, Franklin G. Berger
A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro
Peter Andrews, Xu Zhao, Jeffrey Allen, Fengmin Li, Melissa Chang
Glutamine and alanyl-glutamine accelerate the recovery from 5-fluorouracil-induced experimental oral mucositis in hamster
R. F. C. Leitão, R. A. Ribeiro, A. M. S. Lira, L. R. Silva, E. A. L. Bellaguarda, F. D. B. Macedo, R. B. Sousa, G. A. C. Brito
Pharmacokinetics of gemcitabine in tumor and non-tumor extracellular fluid of brain: an in vivo assessment in rats employing intracerebral microdialysis
Sandhya Kiran Apparaju, Gary A. Gudelsky, Pankaj B. Desai
Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells
David H. Holman, Lorianne S. Turner, Ahmed El-Zawahry, Saeed Elojeimy, Xiang Liu, Jacek Bielawski, Zdzislaw M. Szulc, Kristi Norris, Youssef H. Zeidan, Yusuf A. Hannun, Alicja Bielawska, James S. Norris
Weekly paclitaxel and carboplatin (PC-W) for patients with primary advanced ovarian cancer: results of a multicenter phase-II study of the NOGGO
Jalid Sehouli, Dirk Stengel, Alexander Mustea, Oumar Camara, Elke Keil, Dirk Elling, Peter Ledwon, Bernd Christiansen, Peter Klare, Gerhard Gebauer, Marina Schwarz, Werner Lichtenegger
The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner
Hellinida Thomadaki, Andreas Scorilas, Chris Milto Tsiapalis, Maria Havredaki
Pharmacokinetics of the adrenocorticolytic compounds 3-methylsulphonyl-DDE and o,p′-DDD (mitotane) in Minipigs
Veronica Hermansson, Tatiana Cantillana, Lotta Hovander, Åke Bergman, Karl Ljungvall, Ulf Magnusson, Karolina Törneke, Ingvar Brandt
A phase II study of irinotecan in combination with doxifluridine, an intermediate form of capecitabine, in patients with metastatic colorectal cancer
Takeshi Kato, Hideyuki Mishima, Masakazu Ikenaga, Kouhei Murata, Hideyuki Ishida, Mutsumi Fukunaga, Hirofumi Ota, Shusei Tominaga, Tadashi Ohnishi, Masahiro Amano, Kimimasa Ikeda, Masataka Ikeda, Mitsugu Sekimoto, Junichi Sakamoto, Morito Monden
Phase-II study of dose attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer
Bassel F. El-Rayes, Mark M. Zalupski, Stephanie G. Manza, Barbara Rusin, Ann Marie Ferris, Ulka Vaishampayan, Lance K. Heilbrun, Raghu Venkatramanamoorthy, Anthony F. Shields, Philip A. Philip
Pharmacodynamic characterization of gemcitabine cytotoxicity in an in vitro cell culture bioreactor system
Mark N. Kirstein, Richard C. Brundage, Megan M. Moore, Brent W. Williams, Lisa A. Hillman, Jason W. Dagit, James E. Fisher, Paul H. Marker, Robert A. Kratzke, Douglas Yee
Prognostic factors for survival of patients with advanced gastric cancer treated with cisplatin-based chemotherapy
Jong Gwang Kim, Baek-Yeol Ryoo, Yeon Hee Park, Bong-Seog Kim, Tae-You Kim, Young-Hyuck Im, Yoon-Koo Kang
Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy
Hye Jin Choi, Byoung Chul Cho, Sang Joon Shin, Seong Ha Cheon, Jong Yul Jung, Joon Chang, Se Kyu Kim, Joo Hyuk Sohn, Joo Hang Kim
A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer
Chong Kun Im, Hei-Cheul Jeung, Sun Young Rha, Nae Choon Yoo, Sung Hoon Noh, Jae Kyung Roh, Hyun Cheol Chung
Toxicology and pharmacokinetic study of orally administered 5-iodo-2-pyrimidinone-2′deoxyribose (IPdR) × 28 days in Fischer-344 rats: impact on the initial clinical phase I trial design of IPdR-mediated radiosensitization
Timothy J. Kinsella, Michael T. Kinsella, Seongwon Hong, Jerry P. Johnson, Brian Burback, Patricia J. Tosca
Safety evaluation of oral fluoropyrimidine S-1 for short- and long-term delivery in advanced gastric cancer: analysis of 3,758 patients
Takeharu Yamanaka, Shigemi Matsumoto, Satoshi Teramukai, Ryota Ishiwata, Yoji Nagai, Masanori Fukushima
Reversible paclitaxel-induced vocal cord paralysis with later recall with vinorelbine
Brian S. Choi, H. Ian Robins
Complete remission of a metastatic neuroendocrine tumor of the pancreas with capecitabine (Xeloda®) monotherapy
Gregor Fürstenberger, Peter Schmid, Ans Duquesne, Maria Ammann, Hans-Jörg Senn