Issue 1/2015
Content (23 Articles)
Cytoprotective and regulatory functions of glutathione S-transferases in cancer cell proliferation and cell death
Simendra Singh
Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer
H. S. Hochster, N. Uboha, W. Messersmith, P. J. Gold, B. H. ONeil, D. Cohen, C. Denlinger, S. Cohen, C. G. Leichman, L. Leichman
Erratum to: Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer
H. S. Hochster, N. Uboha, W. Messersmith, P. J. Gold, B. H. ONeil, D. Cohen, C. Denlinger, S. Cohen, C. G. Leichman, L. Leichman, H.-J. Lenz
Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections
Karen D. Wright, John C. Panetta, Arzu Onar-Thomas, Wilburn E. Reddick, Zoltan Patay, Ibrahim Qaddoumi, Alberto Broniscer, Giles Robinson, Frederick A. Boop, Paul Klimo Jr., Deborah Ward, Amar Gajjar, Clinton F. Stewart
A pharmacokinetic and pharmacodynamic investigation of Modufolin® compared to Isovorin® after single dose intravenous administration to patients with colon cancer: a randomized study
Yvonne Wettergren, Helena Taflin, Elisabeth Odin, Karl Kodeda, Kristoffer Derwinger
Pharmacokinetics of abiraterone in healthy Japanese men: dose-proportionality and effect of food timing
Kouichi Inoue, Akira Shishido, Nicole Vaccaro, James Jiao, Hans Stieltjes, Apexa Bernard, Margaret Yu, Caly Chien
Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity
Mette Levinsen, Susanne Rosthøj, Ulrikka Nygaard, Jesper Heldrup, Arja Harila-Saari, Olafur G. Jonsson, Anne Grete Bechensteen, Jonas Abrahamsson, Birgitte Lausen, Thomas L. Frandsen, Richard M. Weinshilboum, Kjeld Schmiegelow
Population pharmacokinetic/dynamic model of lymphosuppression after fludarabine administration
Jeannine S. McCune, Paolo Vicini, David H. Salinger, Paul V. O’Donnell, Brenda M. Sandmaier, Claudio Anasetti, Donald E. Mager
Predictive factors for survival in stage IIIA N2 NSCLC patients treated with neoadjuvant CCRT followed by surgery
Hyun-ju Lim, Ho Yun Lee, Kyung Soo Lee, Jungho Han, O. Jung Kwon, Keunchil Park, Yong Chan Ahn, Byung-Tae Kim, Young Mog Shim
A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and varying degrees of renal function
Sunil Sharma, Petronella O. Witteveen, Martijn P. Lolkema, Dagmar Hess, Hans Gelderblom, Syed A. Hussain, Maria G. Porro, Edward Waldron, Sue-zette Valera, Song Mu
Population pharmacokinetics of HM781-36 (poziotinib), pan-human EGF receptor (HER) inhibitor, and its two metabolites in patients with advanced solid malignancies
Yook-Hwan Noh, Hyeong-Seok Lim, Jin-A Jung, Tae Hun Song, Kyun-Seop Bae
Population pharmacokinetic model of ibrutinib, a Bruton tyrosine kinase inhibitor, in patients with B cell malignancies
Eleonora Marostica, Juthamas Sukbuntherng, David Loury, Jan de Jong, Xavier Woot de Trixhe, An Vermeulen, Giuseppe De Nicolao, Susan O’Brien, John C. Byrd, Ranjana Advani, Jesse McGreivy, Italo Poggesi
Atrial natriuretic peptide protects against cisplatin-induced acute kidney injury
Takashi Nojiri, Hiroshi Hosoda, Toru Kimura, Koichi Miura, Shin Ishikane, Takeshi Tokudome, Yasushi Shintani, Masayoshi Inoue, Mikiya Miyazato, Meinoshin Okumura, Kenji Kangawa
TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts
Jamie L. Croucher, Radhika Iyer, Nanxin Li, Valentina Molteni, Jon Loren, W. Perry Gordon, Tove Tuntland, Bo Liu, Garrett M. Brodeur
Plasma pharmacokinetics and tissue and brain distribution of cisplatin in musk shrews
Julie L. Eiseman, Jan H. Beumer, Lora H. Rigatti, Sandra Strychor, Kelly Meyers, Samuel Dienel, Charles C. Horn
Docetaxel, gemcitabine and bevacizumab as salvage chemotherapy for HER-2-negative metastatic breast cancer
E. Kontopodis, N. Kentepozidis, Ch. Christophyllakis, I. Boukovinas, A. Kalykaki, K. Kalbakis, L. Vamvakas, S. Agelaki, A. Kotsakis, N. Vardakis, V. Georgoulias, D. Mavroudis
Biological evaluation of a novel sorafenib analogue, t-CUPM
Aaron T. Wecksler, Sung Hee Hwang, Jun-Yan Liu, Hiromi I. Wettersten, Christophe Morisseau, Jian Wu, Robert H. Weiss, Bruce D. Hammock
Association of ABCG2 polymorphism with clinical efficacy of imatinib in patients with gastrointestinal stromal tumor
Dong-Hoe Koo, Min-Hee Ryu, Baek-Yeol Ryoo, Mo Youl Beck, Young-Soon Na, Jae-Gook Shin, Sang Seop Lee, Eun-Young Kim, Yoon-Koo Kang
Phase I study of the MEK inhibitor trametinib in combination with the AKT inhibitor afuresertib in patients with solid tumors and multiple myeloma
Anthony W. Tolcher, Amita Patnaik, Kyriakos P. Papadopoulos, Drew W. Rasco, Carlos R. Becerra, Alicia J. Allred, Keith Orford, Gursel Aktan, Geraldine Ferron-Brady, Nageatte Ibrahim, Jennifer Gauvin, Monica Motwani, Mark Cornfeld
Phase I trial of S-1 every other day in combination with gemcitabine/cisplatin for inoperable biliary tract cancer
Tadashi Uwagawa, Taro Sakamoto, Kyohei Abe, Norimitsu Okui, Daigo Hata, Hiroaki Shiba, Yasuro Futagawa, Keisuke Aiba, Katsuhiko Yanaga
EGFR–TKI is effective regardless of treatment timing in pulmonary adenocarcinoma with EGFR mutation
Dong-Hoe Koo, Kyu-pyo Kim, Chang-Min Choi, Dae-Ho Lee, Jae Cheol Lee, Jung-Shin Lee, Se Jin Jang, Sang-We Kim
Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide combination chemotherapy for breast cancer
F. Haroun, L. Al-Shaar, R. H. Habib, N. El-Saghir, A. Tfayli, A. Bazarbachi, Z. Salem, A. Shamseddine, A. Taher, I. Cascorbi, N. K. Zgheib
Sorafenib use in elderly patients with hepatocellular carcinoma: caution about use of platelet aggregation inhibitors
Julien Edeline, Laurence Crouzet, Samuel Le Sourd, Claire Larible, Angélique Brunot, Florence Le Roy, Catherine Cattenoz, Marianne Latournerie, Daniel Gédouin, Anne Guillygomarc’h, Eveline Boucher