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Urolithiasis
Published in: Urolithiasis 6/2012

01-12-2012 | Letter to the Editor

Spontaneous stone passage: is it Ammi visnaga effect?

Authors: Isa Kilicaslan, Selcuk Coskun

Published in: Urolithiasis | Issue 6/2012

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Abstract

Ammi visnaga was used in Ancient Egypt as an herbal remedy for renal colic. “Khellin”, a chemical obtained from Ammi visnaga, was used as a smooth muscle relaxant and has been thought to have pleiotropic effects on urolithiasis. We report a case with multiple ureteral stone passages possibly as a result of medication with an herb preparation, Khellin.
Literature
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Hollingsworth JM, Rogers MA, Kaufman SR, Bradford TJ, Saint S, Wei JT et al (2006) Medical therapy to facilitate urinary stone passage: a meta-analysis. Lancet 368:1171–1179PubMedCrossRef
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Gunaydin K, Beyazit N (2004) The chemical investigations on the ripe fruits of Ammi visnaga (LAM.) Lamarck growing in Turkey. Nat Prod Res 18:169–175PubMedCrossRef
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Meyer U (2002) From khellin to sodium cromoglycate-a tribute to the work of Dr. R. E. C. Altounyan (1922–1987). Pharmazie 57(1):62–69PubMed
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Byer K, Khan SR (2005) Citrate provides protection against oxalate and calcium oxalate crystal induced oxidative damage to renal epithelium. J Urol 173(2):640–646PubMedCrossRef
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Khan ZA, Assiri AM, Al-Afghani HM, Maghrabi TM (2001) Inhibition of oxalate nephrolithiasis with Ammi visnaga (AI-Khillah). Int Urol Nephrol 33(4):605–608PubMedCrossRef
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Vanachayangkul P, Chow N, Khan SR, Butterweck V (2011) Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats. Urol Res 39(3):189–195PubMedCrossRef
Metadata
Title
Spontaneous stone passage: is it Ammi visnaga effect?
Authors
Isa Kilicaslan
Selcuk Coskun
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Urolithiasis / Issue 6/2012
Print ISSN: 2194-7228
Electronic ISSN: 2194-7236
DOI
https://doi.org/10.1007/s00240-012-0509-8

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