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Published in: Journal of Cardiovascular Magnetic Resonance 1/2010

Open Access 01-01-2010 | Technologist presentation

Spoiled Gradient Echo T2* iron-loading measurements of the liver and myocardium in 12 year old male with severely reduced cardiac function from Thalassemia Major

Authors: Annette L Dahl, Taigang He

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2010

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Excerpt

Beta-Thalassemia Major affects 60.000 births per annum world-wide, and a further 94 million carriers. Mutations in the β-globin gene results in severe anaemia, leaving patients dependent on blood transfusions throughout their life. Excessive absorption combined with transfusional haemosiderosis cause iron-overload in the myocardium and liver. There is a 50% mortality rate in Beta-Talassemia Major patients before the age of 35 due to iron overload, with cardiac failure being the main cause of death. …
Metadata
Title
Spoiled Gradient Echo T2* iron-loading measurements of the liver and myocardium in 12 year old male with severely reduced cardiac function from Thalassemia Major
Authors
Annette L Dahl
Taigang He
Publication date
01-01-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1532-429X-12-S1-T3

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