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European Archives of Oto-Rhino-Laryngology

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31-07-2023 | Spirometry | Review Article

Spirometry in laryngotracheal stenosis: a systematic review and meta-analysis

Authors: Waleed Alshareef, Nasser Almutairi, Abdullah Sindi, Latifah Almakoshi, Abdulmajeed Zakzouk, Abdullah Aljasser, Ahmed Alammar

Published in: European Archives of Oto-Rhino-Laryngology | Issue 11/2023

Abstract

Purpose

This study aimed to assess the changes in spirometry parameters or indices after relieving laryngotracheal stenosis (LTS) in adult patients.

Methods

A systematic review and meta-analysis of studies from PubMed, Scopus, Web of Science, Cochrane Library, and EBSCO databases was conducted for assessing changes in spirometry values after endoscopic balloon dilatation of LTS in adults. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Relevant data, such as changes in mean spirometry values between preoperative and postoperative interventions, and findings of receiver operating characteristic curve analyses for predicting the need for surgical intervention, were extracted.

Results

Ten studies including 330 patients overall met the inclusion criteria. Significant improvements were observed from preoperative to postoperative mean values of different spirometry parameters and indices. The overall mean differences in peak expiratory flow (ΔPEF), expiratory disproportion index (ΔEDI), and peak inspiratory flow (ΔPIF) were 2.26 L/s (95% CI 2.14–2.38), 27.94 s (95% CI 26.36–29.52), and 1.21 L/s (95% CI 0.95–1.47), respectively. ΔPEF and ΔPIF values increased, while ΔEDI decreased. In predicting the need for surgical intervention, EDI had the highest sensitivity (88%), and forced expiratory volume per second/forced vital capacity had the highest specificity (85%).

Conclusion

Spirometry is a valuable tool for assessing patients with LTS. PEF, EDI, and PIF were the most commonly reported spirometry parameters that significantly improved after airway stenosis was relieved.

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Title: Spirometry in laryngotracheal stenosis: a systematic review and meta-analysis
Authors: Waleed Alshareef
Nasser Almutairi
Abdullah Sindi
Latifah Almakoshi
Abdulmajeed Zakzouk
Abdullah Aljasser
Ahmed Alammar
Publication date: 31-07-2023
Publisher: Springer Berlin Heidelberg
Keywords: Spirometry
Pulmonary-Function Tests
Published in: European Archives of Oto-Rhino-Laryngology / Issue 11/2023
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08159-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Spirometry in laryngotracheal stenosis: a systematic review and meta-analysis

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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