Skip to main content
Top
Published in: Indian Journal of Surgical Oncology 2/2017

01-06-2017 | Case Report

Spindle Epithelial Tumor with Thymus-like Element (Settle): a Case Report

Authors: Cengiz Tavusbay, Demet Arikan Etit, Ercan Kadioglu, Mehmet Haciyanli

Published in: Indian Journal of Surgical Oncology | Issue 2/2017

Login to get access

Abstract

Spindle epithelial tumor with thymus-like element (SETTLE) is a very rare malignant neoplasm of the thyroid. It is generally encountered in children, adolescents, and young adults Objective: We aimed to present a patient with SETTLE and to review the clinical and pathologic features of this rare tumor. A 13-year-old male patient presented to our clinic with complaints of a rapidly growing lump on his neck. There was no evidence of distant metastases at time of presentation. A total thyroidectomy was performed. Lymph node dissection was not performed. On the first postoperative day, the patient was discharged uneventfully. Histopathological and immunohistochemical analysis revealed a SETTLE in our case. During 1 year of follow-up, the patient had no complaints or symptoms, without tumor recurrence on imaging studies. Although SETTLE is a very rare entity, it should be considered when diagnosing rapidly growing masses in the thyroid, especially in younger patients.
Literature
1.
go back to reference Chan JKC, Rosai J (1991) Tumors of the neck showing thymic or related branchial pouch differentiation: a unifying concept. Human Pathol 22:349–367CrossRef Chan JKC, Rosai J (1991) Tumors of the neck showing thymic or related branchial pouch differentiation: a unifying concept. Human Pathol 22:349–367CrossRef
2.
go back to reference Haberal AN, Aydin H, Turan E, Demirhan B (2008) Unusual spindle cell tumor of thyroid (SETTLE). Thyroid 18:85–87CrossRefPubMed Haberal AN, Aydin H, Turan E, Demirhan B (2008) Unusual spindle cell tumor of thyroid (SETTLE). Thyroid 18:85–87CrossRefPubMed
3.
go back to reference Rastogi A, Saikia UN, Gupta AK, Bhansali A (2012) Recurrent thyroid nodule: spindle epithelial tumor with thymus like differentiation (SETTLE). Indian Pediatr 49:482–484CrossRefPubMed Rastogi A, Saikia UN, Gupta AK, Bhansali A (2012) Recurrent thyroid nodule: spindle epithelial tumor with thymus like differentiation (SETTLE). Indian Pediatr 49:482–484CrossRefPubMed
4.
go back to reference Recondo G Jr, Busaidy N, Erasmus J, Williams MD, Johnson FM (2015) Spindle epithelial tumor with thymus-like differentiation: a case report and comprehensive review of the literature and treatment options. Head Neck 37:746–754CrossRefPubMed Recondo G Jr, Busaidy N, Erasmus J, Williams MD, Johnson FM (2015) Spindle epithelial tumor with thymus-like differentiation: a case report and comprehensive review of the literature and treatment options. Head Neck 37:746–754CrossRefPubMed
5.
go back to reference Llamas-Gutierrez FJ, Falcon-Escobedo R, De Anda-Gonzalez J, Angeles-Angeles A (2013) Spindle epithelial tumor with thymus-like differentiation of the thyroid (SETTLE): report of two cases (one associated with a parathyroid adenoma). Ann Diagn Pathol 17:217–221CrossRefPubMed Llamas-Gutierrez FJ, Falcon-Escobedo R, De Anda-Gonzalez J, Angeles-Angeles A (2013) Spindle epithelial tumor with thymus-like differentiation of the thyroid (SETTLE): report of two cases (one associated with a parathyroid adenoma). Ann Diagn Pathol 17:217–221CrossRefPubMed
6.
go back to reference Kaur J, Srinivasan R, Kakkar N (2012) Fine needle aspiration cytology of a spindle epithelial tumour with thymus-like differentiation (SETTLE) occurring in the thyroid. Cytopathology 23:413–415CrossRefPubMed Kaur J, Srinivasan R, Kakkar N (2012) Fine needle aspiration cytology of a spindle epithelial tumour with thymus-like differentiation (SETTLE) occurring in the thyroid. Cytopathology 23:413–415CrossRefPubMed
7.
go back to reference Cheuk W, Jacobson AA, Chan JK (2000) Spindle epithelial tumor with thymus-like differentiation (SETTLE): a distinctive malignant thyroid neoplasm with significant metastatic potential. Mod Pathol 13:1150–1155CrossRefPubMed Cheuk W, Jacobson AA, Chan JK (2000) Spindle epithelial tumor with thymus-like differentiation (SETTLE): a distinctive malignant thyroid neoplasm with significant metastatic potential. Mod Pathol 13:1150–1155CrossRefPubMed
Metadata
Title
Spindle Epithelial Tumor with Thymus-like Element (Settle): a Case Report
Authors
Cengiz Tavusbay
Demet Arikan Etit
Ercan Kadioglu
Mehmet Haciyanli
Publication date
01-06-2017
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 2/2017
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-016-0607-0

Other articles of this Issue 2/2017

Indian Journal of Surgical Oncology 2/2017 Go to the issue