Top

Graefe's Archive for Clinical and Experimental Ophthalmology

Published in:

01-06-2016 | Cataract

Spherical aberration reduction in nuclear cataracts

Authors: Jong-Hyuck Lee, Hun Gu Choo, Sun Woong Kim

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 6/2016

Abstract

Purpose

To measure higher-order aberrations (HOAs) in nuclear cataracts and to investigate spherical aberration changes with nuclear cataract progression.

Methods

A total of 102 eyes of older subjects (>50 years) were classified based on the nuclear opalescence (NO) grading of the Lens Opacities Classification System III: Group 1 (< NO2, 35), 2 (NO2, 23), 3 (NO3, 23), and 4 (≥ NO 4:21 eyes). Wave front measurements were performed with a Hartmann–Shack aberrometer. To investigate lenticular spherical aberration, HOAs were examined in 28 eyes before and after phacoemulsification, followed by insertion of an aberration-free intraocular lens. The relationship between lens opacity grade and ocular and lenticular spherical aberrations were investigated.

Results

Mean spherical aberrations in groups 1, 2, 3, and 4 were 0.25 ± 0.10, 0.16 ± 0.13, 0.12 ± 0.15, and 0.10 ± 0.20 μm, respectively, and showed a significant difference with nuclear opacity grading (p = 0.001). The spherical aberration showed negative associations with nuclear opacity grading (r = −0.408, p < 0.001). The predominant change in HOAs after phacoemulsification was an increase in spherical aberration, and 86 % of lenticular spherical aberrations were presumed to have negative values. The lenticular spherical aberration was negatively correlated with nuclear opacity severity (r = −0.409, p = 0.031).

Conclusions

Ocular spherical aberration decreases with the progression of nuclear cataracts due to the negative correlation between lenticular spherical aberration and nuclear opacity severity.

Available only for authorised users

Karbassi M, Magnante PC, Wolfe JK, Chylack LT Jr (1993) Objective line spread function measurements, Snellen acuity, and LOCS II classification in patients with cataract. Optom Vis Sci: Off Publ Am Acad Optom 70:956–962CrossRef

Donnelly WJ 3rd, Pesudovs K, Marsack JD, Sarver EJ, Applegate RA (2004) Quantifying scatter in Shack–Hartmann images to evaluate nuclear cataract. J Refract Surg 20:S515–522PubMed

Kuroda T, Fujikado T, Maeda N, Oshika T, Hirohara Y, Mihashi T (2002) Wavefront analysis of higher-order aberrations in patients with cataract. J Cataract Refract Surg 28:438–444CrossRefPubMed

Fujikado T, Kuroda T, Maeda N, Ninomiya S, Goto H, Tano Y, Oshika T, Hirohara Y, Mihashi T (2004) Light scattering and optical aberrations as objective parameters to predict visual deterioration in eyes with cataracts. J Cataract Refract Surg 30:1198–1208. doi:10.1016/j.jcrs.2003.12.023 CrossRefPubMed

Calver RI, Cox MJ, Elliott DB (1999) Effect of aging on the monochromatic aberrations of the human eye. J Opt Soc Am A Opt Image Sci Vis 16:2069–2078CrossRefPubMed

McLellan JS, Marcos S, Burns SA (2001) Age-related changes in monochromatic wave aberrations of the human eye. Invest Ophthalmol Vis Sci 42:1390–1395PubMed

Brunette I, Bueno JM, Parent M, Hamam H, Simonet P (2003) Monochromatic aberrations as a function of age, from childhood to advanced age. Invest Ophthalmol Vis Sci 44:5438–5446CrossRefPubMed

Artal P, Berrio E, Guirao A, Piers P (2002) Contribution of the cornea and internal surfaces to the change of ocular aberrations with age. J Opt Soc Am A Opt Image Sci Vis 19:137–143CrossRefPubMed

Alio JL, Schimchak P, Negri HP, Montes-Mico R (2005) Crystalline lens optical dysfunction through aging. Ophthalmology 112:2022–2029. doi:10.1016/j.ophtha.2005.04.034 CrossRefPubMed

10.

Amano S, Amano Y, Yamagami S, Miyai T, Miyata K, Samejima T, Oshika T (2004) Age-related changes in corneal and ocular higher-order wavefront aberrations. Am J Ophthalmol 137:988–992. doi:10.1016/j.ajo.2004.01.005 CrossRefPubMed

11.

Sachdev N, Ormonde SE, Sherwin T, McGhee CN (2004) Higher-order aberrations of lenticular opacities. J Cataract Refract Surg 30:1642–1648. doi:10.1016/j.jcrs.2004.02.048 CrossRefPubMed

12.

Rocha KM, Nose W, Bottos K, Bottos J, Morimoto L, Soriano E (2007) Higher-order aberrations of age-related cataract. J Cataract Refract Surg 33:1442–1446. doi:10.1016/j.jcrs.2007.03.059 CrossRefPubMed

13.

Kuroda T, Fujikado T, Maeda N, Oshika T, Hirohara Y, Mihashi T (2002) Wavefront analysis in eyes with nuclear or cortical cataract. Am J Ophthalmol 134:1–9CrossRefPubMed

14.

Lee J, Kim MJ, Tchah H (2008) Higher-order aberrations induced by nuclear cataract. J Cataract Refract Surg 34:2104–2109. doi:10.1016/j.jcrs.2008.08.029 CrossRefPubMed

15.

Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY (1993) The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol 111:831–836CrossRefPubMed

16.

Rozema JJ, Van Dyck DE, Tassignon MJ (2005) Clinical comparison of 6 aberrometers. Part 1: Technical specifications. J Cataract Refract Surg 31:1114–1127. doi:10.1016/j.jcrs.2004.11.051 CrossRefPubMed

17.

Guirao A, Tejedor J, Artal P (2004) Corneal aberrations before and after small-incision cataract surgery. Invest Ophthalmol Vis Sci 45:4312–4319. doi:10.1167/iovs.04-0693 CrossRefPubMed

18.

Marcos S, Rosales P, Llorente L, Jimenez-Alfaro I (2007) Change in corneal aberrations after cataract surgery with 2 types of aspherical intraocular lenses. J Cataract Refract Surg 33:217–226. doi:10.1016/j.jcrs.2006.10.021 CrossRefPubMed

19.

Tong N, He JC, Lu F, Wang Q, Qu J, Zhao YE (2008) Changes in corneal wavefront aberrations in microincision and small-incision cataract surgery. J Cataract Refract Surg 34:2085–2090. doi:10.1016/j.jcrs.2008.08.020 CrossRefPubMed

20.

Kim SW, Yang H, Yoon G, Lee YJ, Kweon MN, Kim JK, Seo KY (2011) Higher-order aberration changes after Implantable Collamer Lens implantation for myopia. Am J Ophthalmol 151(653–662), e651. doi:10.1016/j.ajo.2010.10.031

21.

Kim SW, Ahn H, Kim EK, Kim TI (2008) Comparison of higher-order aberrations in eyes with aspherical or spherical intraocular lenses. Eye 22:1493–1498. doi:10.1038/eye.2008.302 CrossRefPubMed

22.

Wang L, Koch DD (2005) Effect of decentration of wavefront-corrected intraocular lenses on the higher-order aberrations of the eye. Arch Ophthalmol 123:1226–1230. doi:10.1001/archopht.123.9.1226 CrossRefPubMed

23.

Wang L, Dai E, Koch DD, Nathoo A (2003) Optical aberrations of the human anterior cornea. J Cataract Refract Surg 29:1514–1521CrossRefPubMed

24.

Brown N (1974) The change in lens curvature with age. Exp Eye Res 19:175–183CrossRefPubMed

25.

Saunders H (1986) A longitudinal study of the age-dependence of human ocular refraction--I. Age-dependent changes in the equivalent sphere. Ophthalmic Physiol Opt: J Br Coll Ophthalmic Opt 6:39–46

26.

Smith G, Atchison DA (2001) The gradient index and spherical aberration of the lens of the human eye. Ophthalmic Physiol Opt:J Br Coll Ophthalmic Opt 21:317–326CrossRef

27.

Smith G, Cox MJ, Calver R, Garner LF (2001) The spherical aberration of the crystalline lens of the human eye. Vis Res 41:235–243CrossRefPubMed

28.

Moffat BA, Atchison DA, Pope JM (2002) Age-related changes in refractive index distribution and power of the human lens as measured by magnetic resonance micro-imaging in vitro. Vis Res 42:1683–1693CrossRefPubMed

29.

Salmon TO, Thibos LN (2002) Videokeratoscope-line-of-sight misalignment and its effect on measurements of corneal and internal ocular aberrations. J Opt Soc Am A Opt Image Sci Vis 19:657–669CrossRefPubMed

Title: Spherical aberration reduction in nuclear cataracts
Authors: Jong-Hyuck Lee
Hun Gu Choo
Sun Woong Kim
Publication date: 01-06-2016
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 6/2016
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-016-3316-z

At a glance: The STEP trials

Springer Medicine

Spherical aberration reduction in nuclear cataracts

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 6/2016

Two-year results of metamorphopsia, visual acuity, and optical coherence tomographic parameters after epiretinal membrane surgery

A pilot study to compartmentalize small melanocytic choroidal tumors and choroidal vessels with speckle-noise free 1050 nm swept source optical coherence tomography (OCT choroidal “tumoropsy”)

A pilot study to image the vascular network of small melanocytic choroidal tumors with speckle noise-free 1050-nm swept source optical coherence tomography (OCT choroidal angiography)

Soft shell technique during vitrectomy for proliferative vitreoretinopathy

Recurrence of macular edema in eyes with branch retinal vein occlusion changes the diameter of unaffected retinal vessels

Reversible structural and functional changes after intraocular pressure reduction in patients with glaucoma