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Journal of Assisted Reproduction and Genetics

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Open Access 01-04-2016 | Case Report

Sperm retrieval and concomitant tumor resection in azoospermic men with congenital adrenal hyperplasia and bilateral testicular adrenal rest tumors: a case report

Authors: Parviz K. Kavoussi, Roxanne B. Summers-Colquitt, Kate C. Odenwald, Megan Kressin, Keikhosrow M. Kavoussi, Thomas B. Pool, Shahryar K. Kavoussi

Published in: Journal of Assisted Reproduction and Genetics | Issue 4/2016

Abstract

Purpose

The objective of this study was to offer a new treatment approach for sperm retrieval simultaneously with tumor resection in azoospermic men with congenital adrenal hyperplasia (CAH), orchialgia, and bilateral testicular adrenal rest tumors (TARTs) who fail to respond to medical treatment.

Methods

This is a retrospective chart review from a couple’s fertility center.

Results

Between May 2013 and May 2015, two azoospermic men with CAH and bilateral TARTs, with orchialgia, and desire to conceive underwent bilateral TART resection in the same surgical setting as sperm retrieval after remaining azoospermic with normalization of gonadotropins with treatment with human chorionic gonadotropin (hCG). Both men had adequate sperm retrieved for in vitro fertilization/intracytoplasmic sperm retrieval (IVF/ICSI) at the time of bilateral TART resections. They had complete TART resections with resolution of orchialgia. The wife of one patient had a successful pregnancy with use of retrieved sperm resulting in a live birth, and the sperm from the other man is cryopreserved for future use.

Conclusions

It is feasible to perform successful sperm retrieval simultaneously with TART resection in azoospermic men with CAH after medical treatments with persistent azoospermia, rather than subjecting these men to multiple invasive procedures.

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Title: Sperm retrieval and concomitant tumor resection in azoospermic men with congenital adrenal hyperplasia and bilateral testicular adrenal rest tumors: a case report
Authors: Parviz K. Kavoussi
Roxanne B. Summers-Colquitt
Kate C. Odenwald
Megan Kressin
Keikhosrow M. Kavoussi
Thomas B. Pool
Shahryar K. Kavoussi
Publication date: 01-04-2016
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 4/2016
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-016-0665-9

At a glance: The STEP trials

Springer Medicine

Sperm retrieval and concomitant tumor resection in azoospermic men with congenital adrenal hyperplasia and bilateral testicular adrenal rest tumors: a case report

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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