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BMC Neurology
Published in: BMC Neurology 1/2009

Open Access 01-12-2009 | Research article

SPEM dysfunction and general schizotypy as measured by the SSQ: a controlled study

Authors: Dirk van Kampen, Jan Berend Deijen

Published in: BMC Neurology | Issue 1/2009

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Abstract

Background

SPEM dysfunction is a well-known phenomenon in schizophrenia. The principal aim of the present study was to examine whether SPEM dysfunction is already observable in subjects scoring high on a specific measure of schizotypy (SSQ General Schizotypy) that was selected because of its intimate relationship with schizophrenic prodromal unfolding.

Methods

Applying ANOVAs, we determined the relationship of subjects' scores on SSQ General Schizotypy and eye movements elicited by targets of different speed. We also examined whether there exists an association between our schizotypy measure and pupil size.

Results

We found more SPEM dysfunction in subjects scoring high on SSQ General Schizotypy than in subjects scoring average on that factor, irrespective of the speed of the target. No relationship was found between baseline pupil size and General Schizotypy.

Conclusion

The present study provides additional evidence that SPEM dysfunction is associated with schizotypic features that precede the onset of schizophrenia and is already observable in general population subjects that show these features.
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Metadata
Title
SPEM dysfunction and general schizotypy as measured by the SSQ: a controlled study
Authors
Dirk van Kampen
Jan Berend Deijen
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2009
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/1471-2377-9-27

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