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BMC Public Health
Published in: BMC Public Health 1/2019

Open Access 01-12-2019 | Research article

Spatial-temporal variation and risk factor analysis of hand, foot, and mouth disease in children under 5 years old in Guangxi, China

Authors: Huan Liu, Genxin Song, Nan He, Shiyan Zhai, Hongquan Song, Yunfeng Kong, Lizhong Liang, Xiaoxiao Liu

Published in: BMC Public Health | Issue 1/2019

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Abstract

Background

Hand, foot and mouth disease (HFMD) incidence is a critical challenge to disease control and prevention in parts of China, particularly Guangxi. However, the association between socioeconomic factors and meteorological factors on HFMD is still unclear.

Methods

This study applied global and local Moran’s I to examine the spatial pattern of HFMD and series analysis to explore the temporal pattern. The effects of meteorological factors and socioeconomic factors on HFMD incidence in Guangxi, China were analyzed using GeoDetector Model.

Results

This study collected 45,522 cases from 87 counties in Guangxi during 2015, among which 43,711 cases were children aged 0–4 years. Temporally, there were two HFMD risk peaks in 2015. One peak was in September with 7890 cases. The other appeared in May with 4687 cases of HFMD. A high-risk cluster was located in the valley areas. The tertiary industry, precipitation and second industry had more influence than other risk factors on HFMD incidence with explanatory powers of 0.24, 0.23 and 0.21, respectively. The interactive effect of any two risk factors would enhance the risk of HFMD.

Conclusions

This study suggests that precipitation and tertiary industry factors might have stronger effects on the HFMD incidence in Guangxi, China, compared with other factors. High-risk of HFMD was identified in the valley areas characterized by high temperature and humidity. Local government should pay more attention and strengthen public health services level in this area.
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Metadata
Title
Spatial-temporal variation and risk factor analysis of hand, foot, and mouth disease in children under 5 years old in Guangxi, China
Authors
Huan Liu
Genxin Song
Nan He
Shiyan Zhai
Hongquan Song
Yunfeng Kong
Lizhong Liang
Xiaoxiao Liu
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2019
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-019-7619-y

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