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Intensive Care Medicine

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01-04-2017 | Correspondence

Some remaining important questions after LUNG SAFE

Discussion of “Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study”

Authors: Didier Dreyfuss, Stéphane Gaudry, Fabiana Madotto, John G. Laffey

Published in: Intensive Care Medicine | Issue 4/2017

Excerpt

The LUNG SAFE study is a major advance in the understanding of epidemiology and prognosis factors of ARDS [1]. …

Laffey JG, Bellani G, Pham T et al (2016) Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study. Intensive Care Med 42:1865–1876. doi:10.1007/s00134-016-4571-5 CrossRefPubMed

Briel M, Meade M, Mercat A et al (2010) Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA 303:865–873CrossRefPubMed

Dreyfuss D, Ricard J-D, Gaudry S (2015) Did studies on HFOV fail to improve ARDS survival because they did not decrease VILI? On the potential validity of a physiological concept enounced several decades ago. Intensive Care Med 41:2076–2086. doi:10.1007/s00134-015-4062-0 CrossRefPubMed

Bellani G, Laffey JG, Pham T, Fan F, Brochard L, Esteban A, Gattinoni L, van Haren F, Larsson A, McAuley DF, Ranieri M, Rubenfeld GD, Thompson BT, Wrigge H, Slutsky AS, Pesenti A, LUNG SAFE Investigarors and ESICM Clinical Trials Group (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315:788–800CrossRefPubMed

Bellani G, Laffey JG, Pham T, Madotto F, Fan E, Brochard L, Esteban A, Gattinoni L, Bumbasirevic V, Piquilloud L, van Haren F, Larsson A, McAuley DF, Bauer PR, Arabi YM, Ranieri M, Antonelli M, Rubenfeld GD, Thompson BT, Wrigge H, Slutsky AS, Pesenti A, on behalf of the LUNG SAFE Investigators, and the ESICM Trials Group (2016) Non-invasive ventilation of patients with ARDS: insights from the LUNG SAFE study. Am J Respir Crit Care Med 195:67–77

Title: Some remaining important questions after LUNG SAFE
Discussion of “Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study”
Authors: Didier Dreyfuss
Stéphane Gaudry
Fabiana Madotto
John G. Laffey
Publication date: 01-04-2017
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 4/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4706-3

At a glance: The STEP trials

Springer Medicine

Some remaining important questions after LUNG SAFE

Discussion of “Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study”

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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