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Journal of Medical Case Reports

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Open Access 01-12-2015 | Case report

Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: two case reports

Authors: A.E. di Lauro, D. Abbate, B. Dell’Angelo, G.A. Iannaccone, F. Scotto, G. Sammartino

Published in: Journal of Medical Case Reports | Issue 1/2015

Abstract

Introduction

Leukocyte-platelet rich fibrin belongs to a second generation of platelet concentrates that does not need biochemical blood manipulation. It is used for tissue healing and regeneration in periodontal and oral-maxillofacial surgery. We report two cases of hyperplastic gingival lesions treated by exeresis and application of leukocyte-platelet rich fibrin membranes in order to improve and accelerate tissue healing.

Case presentation

Two patients (a 78-year-old Caucasian woman and a 30-year-old Caucasian man) were treated for hyperplastic gingival lesions. They underwent to exeresis of lesions and application of leukocyte-platelet rich fibrin membranes. Tissue healing was clinically evaluated after 1, 3, 7, 14 and 30 postoperative days. No recurrences were observed after 2 years of semi-annual follow up.

Conclusions

We obtained rapid and good healing of soft tissues probably due to the elevated content of leukocytes, platelets and growth factors in the leukocyte-platelet rich fibrin. Based on our results we suggest the use of leukocyte-platelet rich fibrin to cover wounds after exeresis of oral neoformations such as hyperplastic gingival lesions.

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Title: Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: two case reports
Authors: A.E. di Lauro
D. Abbate
B. Dell’Angelo
G.A. Iannaccone
F. Scotto
G. Sammartino
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2015
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-015-0714-5

At a glance: The STEP trials

Springer Medicine

Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: two case reports

Abstract

Introduction

Case presentation

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusions

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