Published in:
28-12-2023 | Soft Tissue Infection | REVIEW
Nontuberculous Mycobacterial Infections and Management for the Inpatient Dermatologist
Authors:
Amber Y. Bo, Laura E. Goeser, Karolyn A. Wanat
Published in:
Current Dermatology Reports
|
Issue 4/2023
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Abstract
Purpose of Review
To improve recognition of skin and soft tissue infections caused by nontuberculous mycobacteria (NTM) and provide guidance on diagnostic work-up and treatment for the inpatient dermatologist, with a focus on recent literature (2018–2023).
Recent Findings
The prevalence of NTM skin and soft tissue infections has increased in the last few decades. Histopathology and tissue culture are imperative to make a diagnosis. Matrix-assisted laser deionization-time of flight mass spectrometry (MALDI-TOF MS) is used with increasing frequency to accelerate diagnosis of NTM. Dual antibiotic therapy is recommended to decrease resistance, particularly in rapidly growing bacteria (RGM).
Summary
NTM, particularly RGM, are rare sources of skin and soft tissue infections in hospitalized patients that have high morbidity and mortality. The inpatient dermatologist must maintain a high index of suspicion for NTM cutaneous lesions to initiate work-up and treatment.