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European Archives of Oto-Rhino-Laryngology

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01-04-2019 | Smelling Disorder | Miscellaneous

Olfactory dysfunction in spondyloarthritis

Authors: Esin Yalcinkaya, Mustafa Mert Basaran, Hakan Erdem, Murat Kocyigit, Aytug Altundag, Thomas Hummel

Published in: European Archives of Oto-Rhino-Laryngology | Issue 4/2019

Abstract

Objective

Spondyloarthritis (SpA) is a group of disorders characterized by inflammatory arthritis including ankylosing spondylitis, psoriatic arthritis, reactive arthritis and arthritis-related inflammatory bowel diseases. Recently it has been shown that arthritic disorders are accompanied by olfactory dysfunction. We aimed to specifically investigate the association between spondyloarthritis and olfactory impairment.

Materials and methods

Fifty individuals with SpA and 50 healthy volunteers were included in the study. Olfactory function was evaluated using the “Sniffin’ Sticks” test battery. Additionally, effects of age, gender, activity of the disease, HLA-B27 status, medications, and the duration of disease were included in the analysis.

Results

SpA patients showed significantly lower scores for odor threshold (T), odor discrimination (D) and odor identification (I) than healthy controls (all p < 0.001). In addition, olfactory loss was negatively correlated with the presence of HLA-B27 (Human Leukocyte Antigen), but not with the current activity of the disease (Bath Ankylosing Spondylitis Activity Index). Neither medication nor duration of the disease had a significant effect on the results.

Conclusion

SpA is associated with olfactory loss. Future studies will show whether olfactory function relates to the prognosis of SpA.

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Title: Olfactory dysfunction in spondyloarthritis
Authors: Esin Yalcinkaya
Mustafa Mert Basaran
Hakan Erdem
Murat Kocyigit
Aytug Altundag
Thomas Hummel
Publication date: 01-04-2019
Publisher: Springer Berlin Heidelberg
Keywords: Smelling Disorder
Smelling Disorder
Spondyloarthropathy
Published in: European Archives of Oto-Rhino-Laryngology / Issue 4/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-019-05364-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Olfactory dysfunction in spondyloarthritis

Abstract

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusion

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