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Published in: Sleep and Breathing 2/2020

Open Access 01-06-2020 | Sleep Apnea | Sleep Breathing Physiology and Disorders • Original Article

Automated multi-model deep neural network for sleep stage scoring with unfiltered clinical data

Authors: Xiaoqing Zhang, Mingkai Xu, Yanru Li, Minmin Su, Ziyao Xu, Chunyan Wang, Dan Kang, Hongguang Li, Xin Mu, Xiu Ding, Wen Xu, Xingjun Wang, Demin Han

Published in: Sleep and Breathing | Issue 2/2020

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Abstract

Purpose

To develop an automated framework for sleep stage scoring from PSG via a deep neural network.

Methods

An automated deep neural network was proposed by using a multi-model integration strategy with multiple signal channels as input. All of the data were collected from one single medical center from July 2017 to April 2019. Model performance was evaluated by overall classification accuracy, precision, recall, weighted F1 score, and Cohen’s Kappa.

Results

Two hundred ninety-four sleep studies were included in this study; 122 composed the training dataset, 20 composed the validation dataset, and 152 were used in the testing dataset. The network achieved human-level annotation performance with an average accuracy of 0.8181, weighted F1 score of 0.8150, and Cohen’s Kappa of 0.7276. Top-2 accuracy (the proportion of test samples for which the true label is among the two most probable labels given by the model) was significantly improved compared to the overall classification accuracy, with the average being 0.9602. The number of arousals affected the model’s performance.

Conclusion

This research provides a robust and reliable model with the inter-rater agreement nearing that of human experts. Determining the most appropriate evaluation parameters for sleep staging is a direction for future research.
Appendix
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Metadata
Title
Automated multi-model deep neural network for sleep stage scoring with unfiltered clinical data
Authors
Xiaoqing Zhang
Mingkai Xu
Yanru Li
Minmin Su
Ziyao Xu
Chunyan Wang
Dan Kang
Hongguang Li
Xin Mu
Xiu Ding
Wen Xu
Xingjun Wang
Demin Han
Publication date
01-06-2020
Publisher
Springer International Publishing
Published in
Sleep and Breathing / Issue 2/2020
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-019-02008-w

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