Skip to main content
Top
Published in: Supportive Care in Cancer 4/2009

01-04-2009 | Short Communication

Skin and oral lesions associated to imatinib mesylate therapy

Authors: Fernanda Gonçalves Basso, Camila Cominato Boer, Maria Elvira Pizzigatti Corrêa, Marcia Torrezan, Maria Letícia Cintra, Marina H. C. Gallottini de Magalhães, Paulo da Silva Santos, Cármino Antônio de Souza

Published in: Supportive Care in Cancer | Issue 4/2009

Login to get access

Abstract

Introduction

Imatinib mesylate is a tyrosine kinase inhibitor used to treat chronic myeloid leukemia (CML) throughout all the phases of the disease. In most cases, this drug is well tolerated; however, some cases experience side effects.

Results and discussion

Skin rashes and oral lesions are uncommon and appear to be dose-dependent. The authors report two cases of CML Ph+ in chronic phase patients who presented skin and oral lesions probably induced by imatinib therapy.
Literature
1.
go back to reference Carella AM, Frassoni F, Melo J et al (1997) New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia. Haematologica 82:478–495PubMed Carella AM, Frassoni F, Melo J et al (1997) New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia. Haematologica 82:478–495PubMed
5.
go back to reference Severino G, Chillotti C, De Lisa R et al (2005) Adverse reactions during imatinib and lansoprazole treatment in gastrointestinal stromal tumors. Ann Pharmacother 39:162–164 doi:10.1345/aph.1E127 PubMed Severino G, Chillotti C, De Lisa R et al (2005) Adverse reactions during imatinib and lansoprazole treatment in gastrointestinal stromal tumors. Ann Pharmacother 39:162–164 doi:10.​1345/​aph.​1E127 PubMed
Metadata
Title
Skin and oral lesions associated to imatinib mesylate therapy
Authors
Fernanda Gonçalves Basso
Camila Cominato Boer
Maria Elvira Pizzigatti Corrêa
Marcia Torrezan
Maria Letícia Cintra
Marina H. C. Gallottini de Magalhães
Paulo da Silva Santos
Cármino Antônio de Souza
Publication date
01-04-2009
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 4/2009
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-008-0536-8

Other articles of this Issue 4/2009

Supportive Care in Cancer 4/2009 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine