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International Orthopaedics
Published in: International Orthopaedics 9/2014

01-09-2014 | Review Article

Skeletal tissue regeneration: where can hydrogels play a role?

Authors: Liliana S. Moreira Teixeira, Jennifer Patterson, Frank P. Luyten

Published in: International Orthopaedics | Issue 9/2014

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Abstract

The emerging field of tissue engineering reveals promising approaches for the repair and regeneration of skeletal tissues including the articular cartilage, bone, and the entire joint. Amongst the myriad of biomaterials available to support this strategy, hydrogels are highly tissue mimicking substitutes and thus of great potential for the regeneration of functional tissues. This review comprises an overview of the novel and most promising hydrogels for articular cartilage, osteochondral and bone defect repair. Chondro- and osteo-conductive and -instructive hydrogels are presented, highlighting successful combinations with inductive signals and cell sources. Moreover, advantages, drawbacks, and future perspectives of the role of hydrogels in skeletal regeneration are addressed, pointing out the current state of this rising approach.
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Metadata
Title
Skeletal tissue regeneration: where can hydrogels play a role?
Authors
Liliana S. Moreira Teixeira
Jennifer Patterson
Frank P. Luyten
Publication date
01-09-2014
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 9/2014
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-014-2402-2

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