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European Archives of Oto-Rhino-Laryngology
Published in: European Archives of Oto-Rhino-Laryngology 5/2019

01-05-2019 | Sinus Surgery | Rhinology

Outcomes of endoscopic sinus surgery in adult lung transplant patients with cystic fibrosis

Authors: Paolo Luparello, Maria S. Lazio, Luca Voltolini, Beatrice Borchi, Giovanni Taccetti, Giandomenico Maggiore

Published in: European Archives of Oto-Rhino-Laryngology | Issue 5/2019

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Abstract

Purpose

Cystic Fibrosis (CF) is the most common autosomal recessive disease in Caucasian population. Due to its pathological mechanism, chronic rhino sinusitis (CRS) associated or not with nasal polyposis usually occurs in adults and affects close to one-half of all CF patients. The goal of our work was to evaluate the impact of Endoscopic Sinus Surgery (ESS) in the quality of life (QoL) of the CF patients and demonstrate an improvement of the functional outcomes in the patients underwent the surgical procedure rather than in the not treated ones, particulary in lung transplant patients.

Methods

We studied 54 adult patients affected by CF. Lund–Kennedy, Lund–Mackay scores, and SNOT-22 were analysed. 14 had lung transplant and 9 had both lung tranplant and ESS procedures.

Results

22 (40.7%) out of 54 CF patients underwent ESS. This group presented more likely complaints consistent with CRS. Lund–Kennedy and Lund–Mackay scores appeared higher in the ESS group: 10 (range of 6–12) and 15 (range of 12–20), respectively. SNOT-22 showed median values for non-ESS and ESS group of 20 (range of 3–68) and 40 (range of 10–73), respectively.

Conclusions

ESS represents the best option to improve clinical QoL of CF patients who do not response to conventional medical therapy, with a stabilization of respiratory function after transplantation.
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Metadata
Title
Outcomes of endoscopic sinus surgery in adult lung transplant patients with cystic fibrosis
Authors
Paolo Luparello
Maria S. Lazio
Luca Voltolini
Beatrice Borchi
Giovanni Taccetti
Giandomenico Maggiore
Publication date
01-05-2019
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 5/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05308-9

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