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Graefe's Archive for Clinical and Experimental Ophthalmology

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23-05-2023 | Silicone | Retinal Disorders

Severe anterior persistent fetal vasculature: the role of anterior retinal elongation on prognosis

Authors: Ece Ozdemir Zeydanli, Sengul Ozdek, Burak Acar, Huseyin Baran Ozdemir, Hatice Tuba Atalay

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 10/2023

Abstract

Purpose

This study aims to investigate surgical outcomes of eyes with severe anterior persistent fetal vasculature (PFV) and the role of associated anatomical anomalies on prognosis.

Methods

This is a retrospective, comparative case series of 32 eyes of 31 patients who underwent vitreoretinal surgery for severe anterior PFV, defined as fibrovascular tissue totally covering the back of cataractous lens. Based on the degree of anterior retinal elongations, cases were classified as follows: group 1, eyes with well-developed pars plana and minor/no abnormalities (n = 11, 34%); group 2, eyes with partially developed pars plana and broad-based elongations (n = 9, 28%); and group 3, eyes with no visible pars plana and fibrovascular membrane having 360° continuity with peripheral retina (n = 12, 38%). Complications and functional and anatomical outcomes were investigated.

Results

The median surgical age was 2 (1–12) months. The median follow-up was 26 (6–120) months. Seventy-three percent in group 1 achieved finger counting or better vision with a single surgery and without any pupillary/retinal complication. Groups 2 and 3 required 2.1 ± 0.9 and 2.6 ± 1.2 surgeries on average. Pupillary obliteration and RD occurred in 33% and 22% in group 2 and 58% and 67% in group 3. Retina remained attached after silicone oil removal in 89% of group 2 and 25% of group 3. Phthisis developed in 50% in group 3.

Conclusion

Peripheral retinal anomalies are common in severe anterior PFV and have a major impact on prognosis. Prognosis is favorable in cases with mild-to-moderate anomalies with appropriate management of possible retinal tears. In eyes with 360° retinal elongations, severe fibrous proliferation and eventual eye loss are common.

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Title: Severe anterior persistent fetal vasculature: the role of anterior retinal elongation on prognosis
Authors: Ece Ozdemir Zeydanli
Sengul Ozdek
Burak Acar
Huseyin Baran Ozdemir
Hatice Tuba Atalay
Publication date: 23-05-2023
Publisher: Springer Berlin Heidelberg
Keyword: Silicone
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 10/2023
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-023-06114-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Severe anterior persistent fetal vasculature: the role of anterior retinal elongation on prognosis

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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