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International Ophthalmology

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01-09-2020 | Silicone | Original Paper

Evaluation of emulsified silicone oil with spectral domain-optical coherence tomography and fluorescein angiography

Authors: Zafer Cebeci, Muhammed Talha Sadik, Mehmet Bedii Ogurel, Emre Altinkurt, Nur Kir

Published in: International Ophthalmology | Issue 9/2020

Abstract

Background

To report emulsified particles and related complications after removal of silicone oil (SO) by spectral domain-optical coherence tomography (SD-OCT) and fluorescein angiography (FA).

Methods

A prospective, single-center investigation was performed using SD-OCT, FA and flare cell photometry measurements to evaluate in a cohort of eyes with emulsified silicone particles after removal of long-term SO tamponade.

Results

Nineteen eyes of the 19 patients with emulsified silicone particles detected in ophthalmoscopic exam were included in the study: 13 (68%) were male, and 6 (31.6%) were female, and their mean age was 52.75 ± 16.06 years. Preoperative diagnoses were rhegmatogenous retinal detachment in all eyes. The mean duration of the silicone oil’s presence in the eye was found as 12.63 ± 4.87 (7–26) months. SD-OCT examination postoperatively showed small, round and hyper-reflective structures compatible with emulsified silicone particles on preretinal surface in 7 (36.8%) eyes, intraretinally in 6 (31.6%) eyes and in the vitreous in 12 (63%) eyes. FA imaging demonstrated pearl-like hyper-fluorescence at early and late phases on the large blood vessels in 9 (47.4%) eyes. Late phase hyper-fluorescence due to leakage on the macula was observed in 17 (89.5%) eyes. Diffuse peripheral leakage and hyper-fluorescence was detected in 11 (57.9%) eyes. Flare levels were higher in eyes with emulsified SO compared to unaffected fellow eyes (p < 0.05).

Conclusions

Emulsified silicone particles that remain in the eye may lead to retinal complications and inflammation in addition to their known complications such as keratopathy and glaucoma. The particles that lead to inflammation and presence of inflammation may be examined by imaging methods such as SD-OCT and FA. Removing the SO before emulsification would be suitable for avoiding such complications.

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Title: Evaluation of emulsified silicone oil with spectral domain-optical coherence tomography and fluorescein angiography
Authors: Zafer Cebeci
Muhammed Talha Sadik
Mehmet Bedii Ogurel
Emre Altinkurt
Nur Kir
Publication date: 01-09-2020
Publisher: Springer Netherlands
Keywords: Silicone
Angiography
Published in: International Ophthalmology / Issue 9/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-020-01409-1

At a glance: The STEP trials

Springer Medicine

Evaluation of emulsified silicone oil with spectral domain-optical coherence tomography and fluorescein angiography

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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