Published in:
01-05-2018 | Surgical Symposium Contribution
Short- and Long-Term (10-year) Results of an Organized, Population-Based Breast Cancer Screening Program: Comparative, Observational Study from Hungary
Authors:
Dezső Tóth, Zsolt Varga, Judit Tóth, Péter Árkosy, Éva Sebő
Published in:
World Journal of Surgery
|
Issue 5/2018
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Abstract
Background
A nationwide breast cancer screening program was introduced in Hungary in the year 2002 for women aged 45–65 years to be performed biannually.
Methods
To investigate and report the short-term and 10-year follow-up results, we analyzed our Breast Unit’s prospectively led database of screened (Group A) and age-matched symptomatic (Group B) patients from 2002 to 2007. We compared the clinicopathologic features of tumors and the impact of screening on surgical treatment, as well as the overall (OS), disease-specific (DSS) and disease-free survival (DFS) of different groups.
Results
Data from 208 screen-detected and 101 symptomatic patients between 45 and 65 years of age were examined. Screen-detected women were younger (54 vs. 58.5 years; p = 0.001) had significantly smaller tumors (15.5 vs. 17 mm; p = 0.044), and more breast-conserving surgery (68.8 vs. 59.4%; p = 0.032). Survival statistics were not statistically different at the median follow-up of 123 months; however, there was a trend toward improved DFS in Group A (82.7 vs. 74.3%; p = 0.074).
Conclusions
Our study showed a significant reduction in rates of mastectomy in the screen-detected group in the short term, which does not translate into better survival rates based on initial long-term data. In order to realize the real advantage of this newly enstated screening program, a longer period of investigation is needed.