Skip to main content
Top
Published in: European Journal of Trauma and Emergency Surgery 1/2024

26-05-2023 | Shock | Original Article

Outcome predictors of patients who underwent limb amputation/s following trauma at a level I trauma center in North India

Authors: Parvez Mohi Ud Din Dar, Nida Mir, Anand Kumar Katiyar, Hem Chandra Sati, Pratyusha Priyadarshini, Junaid Alam, Subodh Kumar, Amit Gupta, Sushma Sagar

Published in: European Journal of Trauma and Emergency Surgery | Issue 1/2024

Login to get access

Abstract

Purpose

Limb amputation is one of the oldest medical operations, dating back over 2500 years to Hippocrates' time. In developing countries like India, most of the patients are young, and trauma is the primary cause of limb amputation. The objectives of this study were to investigate the factors that can predict the outcome of patients who underwent upper or lower limb amputations.

Materials and methods

This was a retrospective analysis of the prospectively collected data of patients who underwent limb amputations from January 2015 to December 2019.

Results

From January 2015 to December 2019, 547 patients underwent limb amputations. Males predominated (86%). Road traffic injuries (RTI) were the most common (323, 59%) mechanism of injury. Hemorrhagic shock was present in 125 (22.9%) patients. Above-knee amputation was the most common (33%) amputation procedure performed. The correlation of hemodynamic status at presentation with the outcome was statistically significant (p-0.001). Outcome measures like delayed presentation, hemorrhagic shock, Injury severity scores (ISS), and the new injury severity scores (NISS) were statistically significant (p-0.001) when compared to the outcome. There were 47 (8.6%) mortalities during the study period.

Conclusion

Factors that affected the outcome were delayed presentation, hemorrhagic shock, higher ISS, NISS, MESS scores, surgical-site infection, and associated injuries. Overall mortality during the study was 8.6%.
Literature
1.
go back to reference Van der Meij WKN. No leg to stand on. Historical relation between amputations. Surg Prostheseol. 1995;1:1–256. Van der Meij WKN. No leg to stand on. Historical relation between amputations. Surg Prostheseol. 1995;1:1–256.
2.
go back to reference Paudel B, Shrestha BK, Banskota AK. Two faces of major lower limb amputations. Kathmandu Univ Med J. 2005;3(11):212–6. Paudel B, Shrestha BK, Banskota AK. Two faces of major lower limb amputations. Kathmandu Univ Med J. 2005;3(11):212–6.
3.
go back to reference Umaru RH, Gali BM, Ali N. Role of inappropriate traditional splintage in limb amputation in Maiduguri, Nigeria. Ann Afr Med. 2004;3(3):138–40. Umaru RH, Gali BM, Ali N. Role of inappropriate traditional splintage in limb amputation in Maiduguri, Nigeria. Ann Afr Med. 2004;3(3):138–40.
4.
go back to reference Magee RA. Amputation through the ages the oldest surgical operation. Aust NZ Surg. 1998;68:675–8.CrossRef Magee RA. Amputation through the ages the oldest surgical operation. Aust NZ Surg. 1998;68:675–8.CrossRef
6.
go back to reference Masood J, Irfan A, Ghulam M. Current indications for major lower limb amputation. Pak J Surg. 2008;24(4):228–31. Masood J, Irfan A, Ghulam M. Current indications for major lower limb amputation. Pak J Surg. 2008;24(4):228–31.
7.
go back to reference Greive AC, Lankhorst GJ. Functional outcome of lower-limb amputees: a prospective descriptive study in a general hospital. Prosthet OrthotInt. 1996;20:79–87.CrossRef Greive AC, Lankhorst GJ. Functional outcome of lower-limb amputees: a prospective descriptive study in a general hospital. Prosthet OrthotInt. 1996;20:79–87.CrossRef
8.
go back to reference Pernot HF, Winnubst GM, Cluitmans JJ, De Witte LP. Amputees in Limburg: incidence, morbidity and mortality, prosthetic supply, care utilization and functional level after one year. Prosthet OrthotInt. 2000;24:90–6.CrossRef Pernot HF, Winnubst GM, Cluitmans JJ, De Witte LP. Amputees in Limburg: incidence, morbidity and mortality, prosthetic supply, care utilization and functional level after one year. Prosthet OrthotInt. 2000;24:90–6.CrossRef
9.
go back to reference Rommers GM, Vos LD, Groothoff JW, Schuiling CH. EismaWH: epidemiology of lower limb amputees in the north of The Netherlands: aetiology, discharge destination and prosthetic use. Prosthet Orthot Int. 1997;21(2):92–9.CrossRefPubMed Rommers GM, Vos LD, Groothoff JW, Schuiling CH. EismaWH: epidemiology of lower limb amputees in the north of The Netherlands: aetiology, discharge destination and prosthetic use. Prosthet Orthot Int. 1997;21(2):92–9.CrossRefPubMed
10.
go back to reference Pooja GD, Sangeeta L. Prevalence and aetiology of amputation in Kolkata, India: a retrospective analysis. Hong Kong Physiother J. 2013;31(1):36–40.CrossRef Pooja GD, Sangeeta L. Prevalence and aetiology of amputation in Kolkata, India: a retrospective analysis. Hong Kong Physiother J. 2013;31(1):36–40.CrossRef
11.
go back to reference Saini UC, Hooda A, Aggarwal S, Dhillon MS. Patient profiles of below knee-amputation following road traffic accidents – an observational study from a level 1 trauma centre in India. J Clin Orthop Trauma. 2021;12(1):83–7.CrossRefPubMed Saini UC, Hooda A, Aggarwal S, Dhillon MS. Patient profiles of below knee-amputation following road traffic accidents – an observational study from a level 1 trauma centre in India. J Clin Orthop Trauma. 2021;12(1):83–7.CrossRefPubMed
12.
go back to reference Gopinathan NR, Santhanam SS, Saibaba B, Dhillon MS. Epidemiology of lower limb musculoskeletal trauma with associated vascular injuries in a tertiary care institute in India. Indian J Orthop. 2017;51:199–204.CrossRefPubMedPubMedCentral Gopinathan NR, Santhanam SS, Saibaba B, Dhillon MS. Epidemiology of lower limb musculoskeletal trauma with associated vascular injuries in a tertiary care institute in India. Indian J Orthop. 2017;51:199–204.CrossRefPubMedPubMedCentral
13.
go back to reference Katiyar AK, Agarwal H, Priyadarshini P, Kumar A, Kumar S, Gupta A, Mishra B, Aggarwal R, Soni KD, Mathur P, Sagar R. Primary vs delayed primary closure in patients undergoing lower limb amputation following trauma: a randomised control study. Int Wound J. 2020;17(2):419–28.CrossRefPubMed Katiyar AK, Agarwal H, Priyadarshini P, Kumar A, Kumar S, Gupta A, Mishra B, Aggarwal R, Soni KD, Mathur P, Sagar R. Primary vs delayed primary closure in patients undergoing lower limb amputation following trauma: a randomised control study. Int Wound J. 2020;17(2):419–28.CrossRefPubMed
14.
go back to reference Low EE, Inkellis E, Morshed S. Complications and revision amputation following trauma-related lower limb loss. Injury. 2017;48(2):364–70.CrossRefPubMed Low EE, Inkellis E, Morshed S. Complications and revision amputation following trauma-related lower limb loss. Injury. 2017;48(2):364–70.CrossRefPubMed
15.
go back to reference Kumar GK, Souza CD, Diaz EAI. Incidence and causes of lower-limb amputations in a tertiary care center: evaluation of the medical records in a period of 2 years. Int J Surg. 2018;2(3):16–9. Kumar GK, Souza CD, Diaz EAI. Incidence and causes of lower-limb amputations in a tertiary care center: evaluation of the medical records in a period of 2 years. Int J Surg. 2018;2(3):16–9.
16.
go back to reference Selig HF, Nagele P, Voelckel WG, Trimmel H, Hüpfl M, Lumenta DB, Kamolz LP. The epidemiology of amputation injuries in the Austrian helicopter emergency medical service: a retrospective, nationwide cohort study. Eur J Trauma Emerg Surg. 2012;38(6):651–7.CrossRefPubMed Selig HF, Nagele P, Voelckel WG, Trimmel H, Hüpfl M, Lumenta DB, Kamolz LP. The epidemiology of amputation injuries in the Austrian helicopter emergency medical service: a retrospective, nationwide cohort study. Eur J Trauma Emerg Surg. 2012;38(6):651–7.CrossRefPubMed
17.
go back to reference Deerochanawong C, Home PD, Alberti KG. A survey of lower limb amputation in diabetic patients. Diabetic Med. 1992;9:942–6.CrossRefPubMed Deerochanawong C, Home PD, Alberti KG. A survey of lower limb amputation in diabetic patients. Diabetic Med. 1992;9:942–6.CrossRefPubMed
18.
go back to reference Feinglass J, Pearce WH, Martin GJ, et al. Postoperative and late survival outcomes after major amputation: findings from the department of veteran affairs national surgical quality improvement program. Surgery. 2001;130:21–9.CrossRefPubMed Feinglass J, Pearce WH, Martin GJ, et al. Postoperative and late survival outcomes after major amputation: findings from the department of veteran affairs national surgical quality improvement program. Surgery. 2001;130:21–9.CrossRefPubMed
19.
go back to reference Little JM, Petritsi-jones D, Zylstra P, et al. A survey of amputations for degenerative vascular disease. Med J Aust. 1973;1:329–34.CrossRefPubMed Little JM, Petritsi-jones D, Zylstra P, et al. A survey of amputations for degenerative vascular disease. Med J Aust. 1973;1:329–34.CrossRefPubMed
20.
go back to reference Mabry RL, Holcomb JB, Baker AM, Cloonan CC, Uhorchak JM, Perkins DE, et al. United States army rangers in Somalia: an analysis of combat casualties on an urban battlefield. J Trauma. 2000;49:515–28.CrossRefPubMed Mabry RL, Holcomb JB, Baker AM, Cloonan CC, Uhorchak JM, Perkins DE, et al. United States army rangers in Somalia: an analysis of combat casualties on an urban battlefield. J Trauma. 2000;49:515–28.CrossRefPubMed
21.
go back to reference Kelly JF, Ritenour AE, McLaughlin DF, Bagg KA, Apodaca AN, Mallak CT, et al. Injury severity and causes of death from operation Iraqi freedom and operation enduring freedom: 2003–2004 versus 2006. J Trauma. 2008;64(Suppl):S21–6.PubMed Kelly JF, Ritenour AE, McLaughlin DF, Bagg KA, Apodaca AN, Mallak CT, et al. Injury severity and causes of death from operation Iraqi freedom and operation enduring freedom: 2003–2004 versus 2006. J Trauma. 2008;64(Suppl):S21–6.PubMed
22.
go back to reference Dorlac WC, DeBakey ME, Holcomb JB, Fagan SP, Kwong KL, Dorlac GR, et al. Mortality from isolated civilian penetrating extremity injury. J Trauma. 2005;59:217–22.CrossRefPubMed Dorlac WC, DeBakey ME, Holcomb JB, Fagan SP, Kwong KL, Dorlac GR, et al. Mortality from isolated civilian penetrating extremity injury. J Trauma. 2005;59:217–22.CrossRefPubMed
23.
go back to reference Kragh JF Jr, Walters TJ, Baer DG, Fox CJ, Wade CE, Salinas J, et al. Survival with emergency tourniquet use to stop bleeding in major limb trauma. Ann Surg. 2009;249:1–7.CrossRefPubMed Kragh JF Jr, Walters TJ, Baer DG, Fox CJ, Wade CE, Salinas J, et al. Survival with emergency tourniquet use to stop bleeding in major limb trauma. Ann Surg. 2009;249:1–7.CrossRefPubMed
24.
go back to reference Benfield RJ, Mamczak CN, Vo KC, Smith T, Osborne L, Sheppard FR, Elster EA. Initial predictors associated with outcome in injured multiple traumatic limb amputations: a Kandahar-based combat hospital experience. Injury. 2012;43(10):1753–8.CrossRefPubMed Benfield RJ, Mamczak CN, Vo KC, Smith T, Osborne L, Sheppard FR, Elster EA. Initial predictors associated with outcome in injured multiple traumatic limb amputations: a Kandahar-based combat hospital experience. Injury. 2012;43(10):1753–8.CrossRefPubMed
25.
go back to reference Deng Q, Tang B, Xue C, Liu Y, Liu X, Lv Y, Zhang L. Comparison of the ability to predict mortality between the injury severity score and the new injury severity score: a meta-analysis. Int J Environ Res Public Health. 2016;13(8):825.CrossRefPubMedPubMedCentral Deng Q, Tang B, Xue C, Liu Y, Liu X, Lv Y, Zhang L. Comparison of the ability to predict mortality between the injury severity score and the new injury severity score: a meta-analysis. Int J Environ Res Public Health. 2016;13(8):825.CrossRefPubMedPubMedCentral
26.
go back to reference Bennett PM, Sargeant ID, Midwinter MJ, Penn-Barwell JG. Unilateral lower limb loss following combat injury: medium-term outcomes in British military amputees. Bone Jt J. 2013;95(2):224–9.CrossRef Bennett PM, Sargeant ID, Midwinter MJ, Penn-Barwell JG. Unilateral lower limb loss following combat injury: medium-term outcomes in British military amputees. Bone Jt J. 2013;95(2):224–9.CrossRef
27.
go back to reference Dharm-Datta S, Etherington J, Mistlin A, Rees J, Clasper J. The outcome of British combat amputees in relation to military service. Injury. 2011;42(11):1362–7.CrossRefPubMed Dharm-Datta S, Etherington J, Mistlin A, Rees J, Clasper J. The outcome of British combat amputees in relation to military service. Injury. 2011;42(11):1362–7.CrossRefPubMed
28.
go back to reference Penn-Barwell JG. Outcomes in lower limb amputation following trauma: a systematic review and meta-analysis. Injury. 2011;42:1474–9.CrossRefPubMed Penn-Barwell JG. Outcomes in lower limb amputation following trauma: a systematic review and meta-analysis. Injury. 2011;42:1474–9.CrossRefPubMed
29.
go back to reference Yaşar E, Tok F, Kesikburun S, Ada AM, Kelle B, Göktepe AS, Yazıcıoğlu K, Tan AK. Epidemiologic data of trauma-related lower limb amputees: a single center 10-year experience. Injury. 2017;48(2):349–52.CrossRefPubMed Yaşar E, Tok F, Kesikburun S, Ada AM, Kelle B, Göktepe AS, Yazıcıoğlu K, Tan AK. Epidemiologic data of trauma-related lower limb amputees: a single center 10-year experience. Injury. 2017;48(2):349–52.CrossRefPubMed
30.
go back to reference Brown KV, Murray CK, Clasper JC. Infectious complications of combat-related mangled extremity injuries in the British military. J Trauma. 2010;69(Suppl 1):S109–15.PubMed Brown KV, Murray CK, Clasper JC. Infectious complications of combat-related mangled extremity injuries in the British military. J Trauma. 2010;69(Suppl 1):S109–15.PubMed
31.
go back to reference Pollak AN, Jones AL, Castillo RC, Bosse MJ, MacKenzie EJ. The relationship between time to surgical debridement and incidence of infection after open high-energy lower extremity trauma. J Bone Jt Surg Am. 2010;92:7–15.CrossRef Pollak AN, Jones AL, Castillo RC, Bosse MJ, MacKenzie EJ. The relationship between time to surgical debridement and incidence of infection after open high-energy lower extremity trauma. J Bone Jt Surg Am. 2010;92:7–15.CrossRef
32.
go back to reference Essoh S, Bamba I, Dje VB, Traore A, Lambin Y. Limb amputations in adults in an Ivorian teaching hospital. Niger J Orthop Trauma. 2007;6(2):61–3. Essoh S, Bamba I, Dje VB, Traore A, Lambin Y. Limb amputations in adults in an Ivorian teaching hospital. Niger J Orthop Trauma. 2007;6(2):61–3.
33.
go back to reference Chalya PL, Mabula JB, Dass RM, Ngayomela IH, Chandika AB, Mbelenge N, Gilyoma JM. Major limb amputations: a tertiary hospital experience in northwestern Tanzania. J Orthop Surg Res. 2012;7(1):1–6.CrossRef Chalya PL, Mabula JB, Dass RM, Ngayomela IH, Chandika AB, Mbelenge N, Gilyoma JM. Major limb amputations: a tertiary hospital experience in northwestern Tanzania. J Orthop Surg Res. 2012;7(1):1–6.CrossRef
34.
go back to reference Spoden M, Nimptsch U, Mansky T. Amputation rates of the lower limb by amputation level–observational study using German national hospital discharge data from 2005 to 2015. BMC Health Serv Res. 2019;19(1):1–9. Spoden M, Nimptsch U, Mansky T. Amputation rates of the lower limb by amputation level–observational study using German national hospital discharge data from 2005 to 2015. BMC Health Serv Res. 2019;19(1):1–9.
Metadata
Title
Outcome predictors of patients who underwent limb amputation/s following trauma at a level I trauma center in North India
Authors
Parvez Mohi Ud Din Dar
Nida Mir
Anand Kumar Katiyar
Hem Chandra Sati
Pratyusha Priyadarshini
Junaid Alam
Subodh Kumar
Amit Gupta
Sushma Sagar
Publication date
26-05-2023
Publisher
Springer Berlin Heidelberg
Keywords
Shock
Shock
Published in
European Journal of Trauma and Emergency Surgery / Issue 1/2024
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-023-02273-1

Other articles of this Issue 1/2024

European Journal of Trauma and Emergency Surgery 1/2024 Go to the issue