Published in:
01-12-2017 | Preclinical and Psychophysiology (F Guarraci and L Marson, Section Editors)
Sexual Transmission of Cyst-Forming Coccidian Parasites with Complex Life Cycles
Authors:
Samira Abdulai-Saiku, Wen Han Tong, Ajai Vyas
Published in:
Current Sexual Health Reports
|
Issue 4/2017
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Abstract
Purpose of Review
Cyst-forming heteroxenous Apicomplexan parasites are important parasites of both humans and animals. Here, we discuss currently available evidence of possible sexual transmission of these parasites.
Recent Findings
Seven genera of Apicomplexans are known to have multi-mode, multi-host life cycles. Prior studies have examined the possibility of sexual transmission in three of these genera: Besnoitia, Neospora, and Toxoplasma. There is extensive evidence of sexual transmission of Toxoplasma in several nonhuman animals. However, evidence for the sexual transmission in humans remains equivocal. Sexual transmission of Besnoitia and Neospora has remained contentious given the small number of inconclusive reports.
Summary
It is important to determine if Toxoplasma is a sexually transmitted infection in humans, due to the clinical implications of Toxoplasma in immune-deficient humans and its potential effects on pregnancy. Additionally, this class of parasites can serve as useful perturbation systems to understand the development of virulence and breach of the blood-testes barrier.