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01-06-2013 | Commentary

Sex and severe sepsis

Authors: Bertrand Guidet, Eric Maury

Published in: Critical Care | Issue 3/2013

Abstract

Epidemiological studies document that males are more prone than females to develop severe sepsis and this is confirmed by Sakr and colleagues in the previous issue of Critical Care. However, the impact of gender on prognosis of severe sepsis is a matter of debate. Sakr and colleagues report a higher mortality in septic females than in males. This puzzling result might be explained by confounding factors such as age, nosocomial infections, follow-up period, and case mix. The impact of sexual hormones in older females is less relevant. Treatments aimed at modifying sexual hormone profile are promising but need to be tested in future trials.

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Title: Sex and severe sepsis
Authors: Bertrand Guidet
Eric Maury
Publication date: 01-06-2013
Publisher: BioMed Central
Published in: Critical Care / Issue 3/2013
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc12690

At a glance: The STEP trials

Springer Medicine

Sex and severe sepsis

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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