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01-12-2007 | SHORT COMMUNICATION

Sevoflurane anesthesia decreases cardiac vagal activity and heart rate variability

Authors: Chanannait Paisansathan, MD, Michael Lee, BA, William E. Hoffman, PhD, Peggy Wheeler

Published in: Clinical Autonomic Research | Issue 6/2007

Abstract

We evaluated cardiac vagal activity during sevoflurane anesthesia in neurosurgical patients. Heart rate variability was determined by power spectral analysis and entropy with the patient awake and during sevoflurane anesthesia. High frequency power (0.15–0.50 Hz) and heart rate entropy decreased during sevoflurane and these effects were significantly correlated (r = 0.71 ± 0.12, P < 0.05). The results confirm that cardiac vagal activity was the primary determinant of heart rate variability, which was attenuated by sevoflurane.

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Title: Sevoflurane anesthesia decreases cardiac vagal activity and heart rate variability
Authors: Chanannait Paisansathan, MD
Michael Lee, BA
William E. Hoffman, PhD
Peggy Wheeler
Publication date: 01-12-2007
Publisher: D. Steinkopff-Verlag
Published in: Clinical Autonomic Research / Issue 6/2007
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI: https://doi.org/10.1007/s10286-007-0437-9

At a glance: The STEP trials

Springer Medicine

Sevoflurane anesthesia decreases cardiac vagal activity and heart rate variability

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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