Skip to main content
Top
Published in: International Journal of Pediatric Endocrinology 1/2014

Open Access 01-12-2014 | Research

Severe obesity in children: prevalence, persistence and relation to hypertension

Authors: Joan C Lo, Malini Chandra, Alan Sinaiko, Stephen R Daniels, Ronald J Prineas, Benjamin Maring, Emily D Parker, Nancy E Sherwood, Matthew F Daley, Elyse O Kharbanda, Kenneth F Adams, David J Magid, Patrick J O’Connor, Louise C Greenspan

Published in: International Journal of Pediatric Endocrinology | Issue 1/2014

Login to get access

Abstract

Background

Newer approaches for classifying gradations of pediatric obesity by level of body mass index (BMI) percentage above the 95th percentile have recently been recommended in the management and tracking of obese children. Examining the prevalence and persistence of severe obesity using such methods along with the associations with other cardiovascular risk factors such as hypertension is important for characterizing the clinical significance of severe obesity classification methods.

Methods

This retrospective study was conducted in an integrated healthcare delivery system to characterize obesity and obesity severity in children and adolescents by level of body mass index (BMI) percentage above the 95th BMI percentile, to examine tracking of obesity status over 2–3 years, and to examine associations with blood pressure. Moderate obesity was defined by BMI 100-119% of the 95th percentile and severe obesity by BMI ≥120% × 95th percentile. Hypertension was defined by 3 consecutive blood pressures ≥95th percentile (for age, sex and height) on separate days and was examined in association with obesity severity.

Results

Among 117,618 children aged 6–17 years with measured blood pressure and BMI at a well-child visit during 2007–2010, the prevalence of obesity was 17.9% overall and was highest among Hispanics (28.9%) and blacks (20.5%) for boys, and blacks (23.3%) and Hispanics (21.5%) for girls. Severe obesity prevalence was 5.6% overall and was highest in 12–17 year old Hispanic boys (10.6%) and black girls (9.5%). Subsequent BMI obtained 2–3 years later also demonstrated strong tracking of severe obesity. Stratification of BMI by percentage above the 95th BMI percentile was associated with a graded increase in the risk of hypertension, with severe obesity contributing to a 2.7-fold greater odds of hypertension compared to moderate obesity.

Conclusion

Severe obesity was found in 5.6% of this community-based pediatric population, varied by gender and race/ethnicity (highest among Hispanics and blacks) and showed strong evidence for persistence over several years. Increasing gradation of obesity was associated with higher risk for hypertension, with a nearly three-fold increased risk when comparing severe to moderate obesity, underscoring the heightened health risk associated with severe obesity in children and adolescents.
Appendix
Available only for authorised users
Literature
2.
go back to reference Ogden CL, Carroll MD, Kit BK, Flegal KM: Prevalence of obesity and trends in body mass index among US children and adolescents, 1999–2010. JAMA. 2012, 307: 483-490. 10.1001/jama.2012.40.CrossRefPubMed Ogden CL, Carroll MD, Kit BK, Flegal KM: Prevalence of obesity and trends in body mass index among US children and adolescents, 1999–2010. JAMA. 2012, 307: 483-490. 10.1001/jama.2012.40.CrossRefPubMed
3.
go back to reference Ogden CL, Flegal KM: Changes in terminology for childhood overweight and obesity. Natl Health Stat Report. 2010, 25: 1-5.PubMed Ogden CL, Flegal KM: Changes in terminology for childhood overweight and obesity. Natl Health Stat Report. 2010, 25: 1-5.PubMed
4.
go back to reference Barlow SE: Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics. 2007, 120 (Suppl 4): S164-S192.CrossRefPubMed Barlow SE: Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics. 2007, 120 (Suppl 4): S164-S192.CrossRefPubMed
5.
go back to reference Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH: Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr. 2007, 150: 12-17. 10.1016/j.jpeds.2006.08.042. e12CrossRefPubMed Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH: Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr. 2007, 150: 12-17. 10.1016/j.jpeds.2006.08.042. e12CrossRefPubMed
6.
go back to reference Skelton JA, Cook SR, Auinger P, Klein JD, Barlow SE: Prevalence and trends of severe obesity among US children and adolescents. Acad Pediatr. 2009, 9: 322-329. 10.1016/j.acap.2009.04.005.PubMedCentralCrossRefPubMed Skelton JA, Cook SR, Auinger P, Klein JD, Barlow SE: Prevalence and trends of severe obesity among US children and adolescents. Acad Pediatr. 2009, 9: 322-329. 10.1016/j.acap.2009.04.005.PubMedCentralCrossRefPubMed
7.
go back to reference Wang YC, Gortmaker SL, Taveras EM: Trends and racial/ethnic disparities in severe obesity among US children and adolescents, 1976–2006. Int J Pediatr Obes. 2011, 6: 12-20.CrossRef Wang YC, Gortmaker SL, Taveras EM: Trends and racial/ethnic disparities in severe obesity among US children and adolescents, 1976–2006. Int J Pediatr Obes. 2011, 6: 12-20.CrossRef
8.
go back to reference Woo JG: Using body mass index Z-score among severely obese adolescents: a cautionary note. Int J Pediatr Obes. 2009, 4: 405-410. 10.3109/17477160902957133.CrossRefPubMed Woo JG: Using body mass index Z-score among severely obese adolescents: a cautionary note. Int J Pediatr Obes. 2009, 4: 405-410. 10.3109/17477160902957133.CrossRefPubMed
9.
go back to reference Flegal KM, Wei R, Ogden CL, Freedman DS, Johnson CL, Curtin LR: Characterizing extreme values of body mass index-for-age by using the 2000 centers for disease control and prevention growth charts. Am J Clin Nutr. 2009, 90: 1314-1320. 10.3945/ajcn.2009.28335.CrossRefPubMed Flegal KM, Wei R, Ogden CL, Freedman DS, Johnson CL, Curtin LR: Characterizing extreme values of body mass index-for-age by using the 2000 centers for disease control and prevention growth charts. Am J Clin Nutr. 2009, 90: 1314-1320. 10.3945/ajcn.2009.28335.CrossRefPubMed
10.
go back to reference Kelly AS, Barlow SE, Rao G, Inge TH, Hayman LL, Steinberger J, Urbina EM, Ewing LJ, Daniels SR: Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the american heart association. Circulation. 2013, 128: 1689-1712. 10.1161/CIR.0b013e3182a5cfb3.CrossRefPubMed Kelly AS, Barlow SE, Rao G, Inge TH, Hayman LL, Steinberger J, Urbina EM, Ewing LJ, Daniels SR: Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the american heart association. Circulation. 2013, 128: 1689-1712. 10.1161/CIR.0b013e3182a5cfb3.CrossRefPubMed
11.
go back to reference Gulati AK, Kaplan DW, Daniels SR: Clinical tracking of severely obese children: a new growth chart. Pediatrics. 2012, 130: 1136-1140. 10.1542/peds.2012-0596.PubMedCentralCrossRefPubMed Gulati AK, Kaplan DW, Daniels SR: Clinical tracking of severely obese children: a new growth chart. Pediatrics. 2012, 130: 1136-1140. 10.1542/peds.2012-0596.PubMedCentralCrossRefPubMed
12.
go back to reference Koebnick C, Smith N, Coleman KJ, Getahun D, Reynolds K, Quinn VP, Porter AH, Der-Sarkissian JK, Jacobsen SJ: Prevalence of extreme obesity in a multiethnic cohort of children and adolescents. J Pediatr. 2010, 157: 26-31. 10.1016/j.jpeds.2010.01.025. e22CrossRefPubMed Koebnick C, Smith N, Coleman KJ, Getahun D, Reynolds K, Quinn VP, Porter AH, Der-Sarkissian JK, Jacobsen SJ: Prevalence of extreme obesity in a multiethnic cohort of children and adolescents. J Pediatr. 2010, 157: 26-31. 10.1016/j.jpeds.2010.01.025. e22CrossRefPubMed
13.
go back to reference Lo JC, Sinaiko A, Chandra M, Daley MF, Greenspan LC, Parker ED, Kharbanda EO, Margolis KL, Adams K, Prineas R, Magid D, O'Connor PJ: Prehypertension and hypertension in community-based pediatric practice. Pediatrics. 2013, 131: e415-e424. 10.1542/peds.2012-1292.PubMedCentralCrossRefPubMed Lo JC, Sinaiko A, Chandra M, Daley MF, Greenspan LC, Parker ED, Kharbanda EO, Margolis KL, Adams K, Prineas R, Magid D, O'Connor PJ: Prehypertension and hypertension in community-based pediatric practice. Pediatrics. 2013, 131: e415-e424. 10.1542/peds.2012-1292.PubMedCentralCrossRefPubMed
15.
go back to reference Lo JC, Maring B, Chandra M, Daniels SR, Sinaiko A, Daley MF, Sherwood NE, Kharbanda EO, Parker ED, Adams KF, Prineas RJ, Magid DJ, O'Connor PJ, Greenspan LC: Prevalence of obesity and extreme obesity in children aged 3–5 years. Pediatric Obesity. 2013 Lo JC, Maring B, Chandra M, Daniels SR, Sinaiko A, Daley MF, Sherwood NE, Kharbanda EO, Parker ED, Adams KF, Prineas RJ, Magid DJ, O'Connor PJ, Greenspan LC: Prevalence of obesity and extreme obesity in children aged 3–5 years. Pediatric Obesity. 2013
17.
go back to reference National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents: The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004, 114: 555-576.CrossRef National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents: The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004, 114: 555-576.CrossRef
18.
go back to reference Biro FM, Huang B, Morrison JA, Horn PS, Daniels SR: Body mass index and waist-to-height changes during teen years in girls are influenced by childhood body mass index. J Adolesc Health. 2010, 46: 245-250. 10.1016/j.jadohealth.2009.06.023.PubMedCentralCrossRefPubMed Biro FM, Huang B, Morrison JA, Horn PS, Daniels SR: Body mass index and waist-to-height changes during teen years in girls are influenced by childhood body mass index. J Adolesc Health. 2010, 46: 245-250. 10.1016/j.jadohealth.2009.06.023.PubMedCentralCrossRefPubMed
19.
go back to reference Thompson DR, Obarzanek E, Franko DL, Barton BA, Morrison J, Biro FM, Daniels SR, Striegel-Moore RH: Childhood overweight and cardiovascular disease risk factors: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr. 2007, 150: 18-25. 10.1016/j.jpeds.2006.09.039.PubMedCentralCrossRefPubMed Thompson DR, Obarzanek E, Franko DL, Barton BA, Morrison J, Biro FM, Daniels SR, Striegel-Moore RH: Childhood overweight and cardiovascular disease risk factors: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr. 2007, 150: 18-25. 10.1016/j.jpeds.2006.09.039.PubMedCentralCrossRefPubMed
20.
go back to reference Kvaavik E, Tell GS, Klepp KI: Predictors and tracking of body mass index from adolescence into adulthood: follow-up of 18 to 20 years in the Oslo Youth Study. Arch Pediatr Adolesc Med. 2003, 157: 1212-1218. 10.1001/archpedi.157.12.1212.CrossRefPubMed Kvaavik E, Tell GS, Klepp KI: Predictors and tracking of body mass index from adolescence into adulthood: follow-up of 18 to 20 years in the Oslo Youth Study. Arch Pediatr Adolesc Med. 2003, 157: 1212-1218. 10.1001/archpedi.157.12.1212.CrossRefPubMed
21.
go back to reference Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH: Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med. 1997, 337: 869-873. 10.1056/NEJM199709253371301.CrossRefPubMed Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH: Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med. 1997, 337: 869-873. 10.1056/NEJM199709253371301.CrossRefPubMed
22.
go back to reference Guo SS, Wu W, Chumlea WC, Roche AF: Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr. 2002, 76: 653-658.PubMed Guo SS, Wu W, Chumlea WC, Roche AF: Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr. 2002, 76: 653-658.PubMed
23.
go back to reference Morrison JA, Glueck CJ, Daniels SR, Wang P: Race, childhood insulin, childhood caloric intake, and class 3 obesity at age 24: 14-year prospective study of schoolgirls. Obesity (Silver Spring). 2012, 20: 597-604. 10.1038/oby.2011.126.CrossRef Morrison JA, Glueck CJ, Daniels SR, Wang P: Race, childhood insulin, childhood caloric intake, and class 3 obesity at age 24: 14-year prospective study of schoolgirls. Obesity (Silver Spring). 2012, 20: 597-604. 10.1038/oby.2011.126.CrossRef
24.
go back to reference Marcus MD, Foster GD, El Ghormli L, Baranowski T, Goldberg L, Jago R, Linder B, Steckler A, Trevino R: Shifts in BMI category and associated cardiometabolic risk: prospective results from HEALTHY study. Pediatrics. 2012, 129: e983-e991. 10.1542/peds.2011-2696.PubMedCentralCrossRefPubMed Marcus MD, Foster GD, El Ghormli L, Baranowski T, Goldberg L, Jago R, Linder B, Steckler A, Trevino R: Shifts in BMI category and associated cardiometabolic risk: prospective results from HEALTHY study. Pediatrics. 2012, 129: e983-e991. 10.1542/peds.2011-2696.PubMedCentralCrossRefPubMed
25.
go back to reference Charakida M, Jones A, Falaschetti E, Khan T, Finer N, Sattar N, Hingorani A, Lawlor DA, Smith GD, Deanfield JE: Childhood obesity and vascular phenotypes: a population study. J Am Coll Cardiol. 2012, 60: 2643-2650. 10.1016/j.jacc.2012.08.1017.CrossRefPubMed Charakida M, Jones A, Falaschetti E, Khan T, Finer N, Sattar N, Hingorani A, Lawlor DA, Smith GD, Deanfield JE: Childhood obesity and vascular phenotypes: a population study. J Am Coll Cardiol. 2012, 60: 2643-2650. 10.1016/j.jacc.2012.08.1017.CrossRefPubMed
26.
go back to reference Sorof J, Daniels S: Obesity hypertension in children: a problem of epidemic proportions. Hypertension. 2002, 40: 441-447. 10.1161/01.HYP.0000032940.33466.12.CrossRefPubMed Sorof J, Daniels S: Obesity hypertension in children: a problem of epidemic proportions. Hypertension. 2002, 40: 441-447. 10.1161/01.HYP.0000032940.33466.12.CrossRefPubMed
27.
go back to reference Sorof JM, Poffenbarger T, Franco K, Bernard L, Portman RJ: Isolated systolic hypertension, obesity, and hyperkinetic hemodynamic states in children. J Pediatr. 2002, 140: 660-666. 10.1067/mpd.2002.125228.CrossRefPubMed Sorof JM, Poffenbarger T, Franco K, Bernard L, Portman RJ: Isolated systolic hypertension, obesity, and hyperkinetic hemodynamic states in children. J Pediatr. 2002, 140: 660-666. 10.1067/mpd.2002.125228.CrossRefPubMed
28.
go back to reference Flynn J: The changing face of pediatric hypertension in the era of the childhood obesity epidemic. Pediatr Nephrol. 2013, 28: 1059-1066. 10.1007/s00467-012-2344-0.CrossRefPubMed Flynn J: The changing face of pediatric hypertension in the era of the childhood obesity epidemic. Pediatr Nephrol. 2013, 28: 1059-1066. 10.1007/s00467-012-2344-0.CrossRefPubMed
29.
go back to reference Tu W, Eckert GJ, DiMeglio LA, Yu Z, Jung J, Pratt JH: Intensified effect of adiposity on blood pressure in overweight and obese children. Hypertension. 2011, 58: 818-824. 10.1161/HYPERTENSIONAHA.111.175695.PubMedCentralCrossRefPubMed Tu W, Eckert GJ, DiMeglio LA, Yu Z, Jung J, Pratt JH: Intensified effect of adiposity on blood pressure in overweight and obese children. Hypertension. 2011, 58: 818-824. 10.1161/HYPERTENSIONAHA.111.175695.PubMedCentralCrossRefPubMed
30.
go back to reference Ice CL, Murphy E, Cottrell L, Neal WA: Morbidly obese diagnosis as an indicator of cardiovascular disease risk in children: results from the CARDIAC Project. Int J Pediatr Obes. 2011, 6: 113-119. 10.3109/17477161003792556.CrossRefPubMed Ice CL, Murphy E, Cottrell L, Neal WA: Morbidly obese diagnosis as an indicator of cardiovascular disease risk in children: results from the CARDIAC Project. Int J Pediatr Obes. 2011, 6: 113-119. 10.3109/17477161003792556.CrossRefPubMed
31.
go back to reference Valerio G, Maffeis C, Balsamo A, Del Giudice EM, Brufani C, Grugni G, Licenziati MR, Brambilla P, Manco M: Severe obesity and cardiometabolic risk in children: comparison from two international classification systems. PloS One. 2013, 8: e83793-10.1371/journal.pone.0083793.PubMedCentralCrossRefPubMed Valerio G, Maffeis C, Balsamo A, Del Giudice EM, Brufani C, Grugni G, Licenziati MR, Brambilla P, Manco M: Severe obesity and cardiometabolic risk in children: comparison from two international classification systems. PloS One. 2013, 8: e83793-10.1371/journal.pone.0083793.PubMedCentralCrossRefPubMed
32.
go back to reference Marcus MD, Baranowski T, DeBar LL, Edelstein S, Kaufman FR, Schneider M, Siega-Riz AM, Staten MA, Virus A, Yin Z: Severe obesity and selected risk factors in a sixth grade multiracial cohort: the HEALTHY study. J Adolesc Health. 2010, 47: 604-607. 10.1016/j.jadohealth.2010.04.017.PubMedCentralCrossRefPubMed Marcus MD, Baranowski T, DeBar LL, Edelstein S, Kaufman FR, Schneider M, Siega-Riz AM, Staten MA, Virus A, Yin Z: Severe obesity and selected risk factors in a sixth grade multiracial cohort: the HEALTHY study. J Adolesc Health. 2010, 47: 604-607. 10.1016/j.jadohealth.2010.04.017.PubMedCentralCrossRefPubMed
33.
go back to reference Gomez-Marin O, Prineas RJ, Rastam L: Cuff bladder width and blood pressure measurement in children and adolescents. J Hypertens. 1992, 10: 1235-1241. 10.1097/00004872-199210000-00018.CrossRefPubMed Gomez-Marin O, Prineas RJ, Rastam L: Cuff bladder width and blood pressure measurement in children and adolescents. J Hypertens. 1992, 10: 1235-1241. 10.1097/00004872-199210000-00018.CrossRefPubMed
34.
go back to reference Whincup PH, Cook DG, Shaper AG: Blood pressure measurement in children: the importance of cuff bladder size. J Hypertens. 1989, 7: 845-850. 10.1097/00004872-198910000-00010.CrossRefPubMed Whincup PH, Cook DG, Shaper AG: Blood pressure measurement in children: the importance of cuff bladder size. J Hypertens. 1989, 7: 845-850. 10.1097/00004872-198910000-00010.CrossRefPubMed
Metadata
Title
Severe obesity in children: prevalence, persistence and relation to hypertension
Authors
Joan C Lo
Malini Chandra
Alan Sinaiko
Stephen R Daniels
Ronald J Prineas
Benjamin Maring
Emily D Parker
Nancy E Sherwood
Matthew F Daley
Elyse O Kharbanda
Kenneth F Adams
David J Magid
Patrick J O’Connor
Louise C Greenspan
Publication date
01-12-2014
Publisher
BioMed Central
Published in
International Journal of Pediatric Endocrinology / Issue 1/2014
Electronic ISSN: 1687-9856
DOI
https://doi.org/10.1186/1687-9856-2014-3

Other articles of this Issue 1/2014

International Journal of Pediatric Endocrinology 1/2014 Go to the issue

Reviewer acknowledgement

Reviewer acknowledgement 2013