Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2008

Open Access 01-12-2008 | Case report

Severe generalised hypersensitivity reaction to topical neomycin after cataract surgery: a case report

Authors: Imran A Ansari, Ernest Onyema

Published in: Journal of Medical Case Reports | Issue 1/2008

Login to get access

Abstract

Introduction

Systemic hypersensitivity reactions to topical ophthalmic treatment occur rarely, but when they do they can be severe as highlighted by this case.

Case presentation

A post-operative cataract surgery patient developed a severe and generalised hypersensitivity reaction following topical treatment with Maxitrol (Dexamethasone and Neomycin) eye drops. The patient reported a previous allergic reaction to Neomycin.

Conclusion

This case report emphasises the importance of a thorough drug and allergy history when patients are seen at pre-assessment or clerked in for surgery.
Appendix
Available only for authorised users
Literature
1.
go back to reference Wilson FM: Adverse external ocular effects of topical ophthalmic therapy: an epidemiologic, laboratory, and clinical study. Trans Am Ophthalmol Soc. 1983, 81: 854-965.PubMedPubMedCentral Wilson FM: Adverse external ocular effects of topical ophthalmic therapy: an epidemiologic, laboratory, and clinical study. Trans Am Ophthalmol Soc. 1983, 81: 854-965.PubMedPubMedCentral
2.
go back to reference Wilson , Fred M: Allergy to Topical Medications. International Ophthalmology Clinics. Recent Trends in Ocular Allergy. 2003, 43 (1): 73-81. Winter Wilson , Fred M: Allergy to Topical Medications. International Ophthalmology Clinics. Recent Trends in Ocular Allergy. 2003, 43 (1): 73-81. Winter
3.
go back to reference Wilson FM: Adverse external ocular effects of topical ophthalmic medications. Surv Ophthalmol. 1979, 24: 57-88. 10.1016/0039-6257(79)90125-5.CrossRefPubMed Wilson FM: Adverse external ocular effects of topical ophthalmic medications. Surv Ophthalmol. 1979, 24: 57-88. 10.1016/0039-6257(79)90125-5.CrossRefPubMed
4.
go back to reference Stern GA, Knapp A: Iatrogenic peripheral corneal disease. Int Ophthalmol Clin. 1986, 26: 77-89. 10.1097/00004397-198602640-00008.CrossRefPubMed Stern GA, Knapp A: Iatrogenic peripheral corneal disease. Int Ophthalmol Clin. 1986, 26: 77-89. 10.1097/00004397-198602640-00008.CrossRefPubMed
5.
go back to reference Wise DJ, Carter GR: Immunology. A comprehensive review. 2002, Ames, Iowa: Iowa State University Press Wise DJ, Carter GR: Immunology. A comprehensive review. 2002, Ames, Iowa: Iowa State University Press
6.
go back to reference Baldinger J, Weiter JJ: Diffuse cutaneous hypersensitivity reaction after dexamethasone/polymyxin B/neomycin combination eye drops. Source Annals of Ophthalmology. 1986, 18 (3): 95-6. Baldinger J, Weiter JJ: Diffuse cutaneous hypersensitivity reaction after dexamethasone/polymyxin B/neomycin combination eye drops. Source Annals of Ophthalmology. 1986, 18 (3): 95-6.
7.
go back to reference de Pádua CA, Uter W, Schnuch A: Contact allergy to topical drugs: prevalence in a clinical setting and estimation of frequency at the population level. Pharmacoepidemiol Drug Saf. 2007, 16 (4): 377-84. 10.1002/pds.1268.CrossRefPubMed de Pádua CA, Uter W, Schnuch A: Contact allergy to topical drugs: prevalence in a clinical setting and estimation of frequency at the population level. Pharmacoepidemiol Drug Saf. 2007, 16 (4): 377-84. 10.1002/pds.1268.CrossRefPubMed
Metadata
Title
Severe generalised hypersensitivity reaction to topical neomycin after cataract surgery: a case report
Authors
Imran A Ansari
Ernest Onyema
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2008
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-2-57

Other articles of this Issue 1/2008

Journal of Medical Case Reports 1/2008 Go to the issue