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Pediatric Radiology
Published in: Pediatric Radiology 2/2008

01-02-2008 | Case Report

Severe cerebellitis following methadone poisoning

Authors: Fionnghuala Mills, Suzanna C. MacLennan, Catherine J. Devile, Dawn E. Saunders

Published in: Pediatric Radiology | Issue 2/2008

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Abstract

We report a 3-year-old girl with an unusual presentation of cerebellitis following ingestion of methadone. CT showed diffuse symmetrical swelling and oedema of the cerebellum resulting in compression of the fourth ventricle and hydrocephalus. The changes were confirmed on MRI with the addition of watershed injuries. These findings represent a toxic encephalopathy and have been reported in previous cases of heroin intoxication by inhalation, but rarely following opioid ingestion. The aetiology of the watershed infarcts is discussed.
Literature
1.
Montenegro MA, Santos SL, Li LM et al (2002) Neuroimaging of acute cerebellitis. J Neuroimaging 12:72–74PubMedCrossRef
2.
Bakshi R, Bates VE, Kinkel PR et al (1998) Magnetic resonance imaging findings in acute cerebellitis. Clin Imaging 22:79–85PubMedCrossRef
3.
Anselmo M, Campos Rainho A, do Carmo Vale M et al (2006) Methadone intoxication in a child: toxic encephalopathy? J Child Neurol 21:618–620PubMedCrossRef
4.
Roulet Perez E, Maeder P, Rivier L et al (1992) Toxic leucoencephalopathy after heroin ingestion in a 2½ year old child. Lancet 340:729PubMedCrossRef
5.
Nanan R, von Stockhausen HB, Petersen B et al (2000) Unusual pattern of leukoencephalopathy after morphine sulphate intoxication. Neuroradiology 42:845–848PubMedCrossRef
6.
Keogh C, Andrews G, Spacey S et al (2003) Neuroimaging features of heroin inhalation toxicity: “Chasing the Dragon”. AJR 180:847–850PubMed
7.
Hagel J, Andrews G, Vertinsky T et al (2005) “Chasing the Dragon”. Imaging of heroin inhalation leukoencephalopathy. Neuroradiology 56:199–203
Metadata
Title
Severe cerebellitis following methadone poisoning
Authors
Fionnghuala Mills
Suzanna C. MacLennan
Catherine J. Devile
Dawn E. Saunders
Publication date
01-02-2008
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 2/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-007-0635-6

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