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01-06-2013 | Note

Seroprevalence of Chlamydophila pneumoniae in HIV-infected children in Vietnam

Authors: Quang Duy Trinh, Ngan Thi Kim Pham, Nhut Tin Le Nguyen, Bao Quoc Lam, Kim Thoa Le Phan, Khanh Huu Truong, Thinh Quoc Le, Hung Thanh Nguyen, Thuong Chi Tang, Yasuyuki Izumi, Shihoko Komine-Aizawa, Hiroshi Ushijima, Satoshi Hayakawa

Published in: Journal of Infection and Chemotherapy | Issue 3/2013

Abstract

A total of 89 blood samples collected from HIV-infected infants and children from provinces of southern Vietnam who were hospitalized at Children’s Hospital 1, Ho Chi Minh City, during the 1-year period from October 2004 to September 2005 were submitted to serological screening for IgG, IgA, and IgM antibodies against Chlamydophila pneumoniae (C. pneumoniae). The presence of this microorganism was also evaluated by PCR. The results showed that 64 % of the samples were positive for anti-C. pneumoniae IgG, 31.5 % were positive for IgA, and 3.4 % were positive for IgM. The highest prevalences of IgG and IgA positivity, 75 % and 66.7 %, respectively, were noted in the 1- to 2-year-old age group. However, all the samples were negative for C. pneumoniae by PCR. The study revealed a high seroprevalence of C. pneumoniae in Vietnamese infants and children with HIV/AIDS.

Grayston JT. Chlamydia pneumoniae, strain TWAR pneumonia. Annu Rev Med. 1992;43:317–23.PubMedCrossRef

Montes M, Cilla G, Alcorta M, Perez-Trallero E. High prevalence of Chlamydia pneumoniae infection in children and young adults in Spain. Pediatr Infect Dis J. 1992;11:972–3.PubMedCrossRef

Ben-Yaakov M, Lazarovich Z, Beer S, Levin A, Shoham I, Boldur I. Prevalence of Chlamydia pneumoniae antibodies in patients with acute respiratory infections in Israel. J Clin Pathol. 1994;47:232–5.PubMedCrossRef

Gaydos CA, Roblin PM, Hammerschlag MR, Hyman CL, Eiden JJ, Schachter J, et al. Quinn TC. Diagnostic utility of PCR-enzyme immunoassay, culture, and serology for detection of Chlamydia pneumoniae in symptomatic and asymptomatic patients. J Clin Microbiol. 1994;32:903–5.PubMed

Hyman CL, Roblin PM, Gaydos CA, Quinn TC, Schachter J, Hammerschlag MR. Prevalence of asymptomatic nasopharyngeal carriage of Chlamydia pneumoniae in subjectively healthy adults: assessment by polymerase chain reaction-enzyme immunoassay and culture. Clin Infect Dis. 1995;20:1174–8.PubMedCrossRef

Koh WP, Taylor MB, Hughes K, Chew SK, Fong CW, Phoon MC, et al. Seroprevalence of IgG antibodies against Chlamydia pneumoniae in Chinese, Malays and Asian Indians in Singapore. Int J Epidemiol. 2002;31:1001–7.PubMedCrossRef

Miyashita N, Fukano H, Yoshida K, Niki Y, Matsushima T. Seroepidemiology of Chlamydia pneumoniae in Japan between 1991 and 2000. J Clin Pathol. 2002;55:115–7.PubMedCrossRef

Lin TM, Kuo CC, Chen WJ, Lin FJ, Eng HL. Seroprevalence of Chlamydia pneumoniae infection in Taiwan. J Infect. 2004;48:91–5.PubMedCrossRef

Cosentini R, Esposito S, Blasi F, Clerici Schoeller M, Pinzani R, Tarsia P, et al. Incidence of Chlamydia pneumoniae infection in vertically HIV-1 infected children. Eur J Clin Microbiol Infect Dis. 1998;17:720–3.PubMedCrossRef

10.

Plebani A, Schoeller MC, Blasi F, Cosentini R. Preliminary data on Chlamydia pneumoniae seroprevalence in HIV-1 infected children. Ann N Y Acad Sci. 1993;693:286–7.PubMedCrossRef

11.

Monno R, Leone E, Maggi P, Buccoliero G, Valenza MA, Angarano G. Chlamydia pneumoniae: a new opportunistic infectious agent in AIDS? Clin Microbiol Infect. 1997;3:187–91.PubMedCrossRef

12.

Trinh QD, Pham NT, Lam BQ, Le TP, Truong KH, Le TQ, et al. Subtyping and env C2/V3 sequence analysis of HIV-1 isolated from HIV-infected children hospitalized in Children Hospital 1, Vietnam during 2004–2005. J Trop Pediatr. 2009;55:399–401.PubMedCrossRef

13.

Tong CY, Sillis M. Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR. J Clin Pathol. 1993;46:313–7.PubMedCrossRef

14.

Iijima Y, Miyashita N, Kishimoto T, Kanamoto Y, Soejima R, Matsumoto A. Characterization of Chlamydia pneumoniae species-specific proteins immunodominant in humans. J Clin Microbiol. 1994;32:583–8.PubMed

15.

Tositti G, Rassu M, Fabris P, Giordani M, Cazzavillan S, Reatto P, et al. Chlamydia pneumoniae infection in HIV-positive patients: prevalence and relationship with lipid profile. HIV Med. 2005;6:27–32.PubMedCrossRef

Title: Seroprevalence of Chlamydophila pneumoniae in HIV-infected children in Vietnam
Authors: Quang Duy Trinh
Ngan Thi Kim Pham
Nhut Tin Le Nguyen
Bao Quoc Lam
Kim Thoa Le Phan
Khanh Huu Truong
Thinh Quoc Le
Hung Thanh Nguyen
Thuong Chi Tang
Yasuyuki Izumi
Shihoko Komine-Aizawa
Hiroshi Ushijima
Satoshi Hayakawa
Publication date: 01-06-2013
Publisher: Springer Japan
Published in: Journal of Infection and Chemotherapy / Issue 3/2013
Print ISSN: 1341-321X
Electronic ISSN: 1437-7780
DOI: https://doi.org/10.1007/s10156-012-0483-7

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