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Critical Care
Published in: Critical Care 1/2020

01-12-2020 | Septicemia | Research Letter

Substrate utilization and energy expenditure pattern in sepsis by indirect calorimetry

Authors: Andrew Li, Amartya Mukhopadhyay

Published in: Critical Care | Issue 1/2020

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Excerpt

Temporal metabolic profiles in sepsis are altered by the hormonal changes related to reduced food intake before admission and fasting after mechanical ventilation (MV), followed by refeeding [1]. Animal models suggest that preterminal rats were hypometabolic, compared to surviving animals [2]. This was further corroborated among septic patients, where higher metabolic rates and lower respiratory quotients (RQ) were observed [3]. However, longitudinal data using indirect calorimetry (IC) remain sparse. We aimed to determine the temporal trends of energy expenditure (EE) and RQ among septic patients receiving MV. …
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Fried RC, Bailey PM, Mullen JL, Stein TP, Crosby LO, Buzby GP. Alterations in exogenous substrate metabolism in sepsis. Arch Surg. 1986;121:173–8.CrossRef
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Giovannini I, Boldrini G, Castagneto M, Sganga G, Nanni G, Pittiruti M, et al. Respiratory quotient and patterns of substrate utilization in human sepsis and trauma. JPEN J Parenter Enteral Nutr. 1983;7:226–30.CrossRef
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Wischmeyer PE, San-Millan I. Winning the war against ICU-acquired weakness: new innovations in nutrition and exercise physiology. Crit Care. 2015;19(Suppl 3):S6.CrossRef
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Metadata
Title
Substrate utilization and energy expenditure pattern in sepsis by indirect calorimetry
Authors
Andrew Li
Amartya Mukhopadhyay
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03245-2

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