Published in:
Open Access
01-01-2018 | Clinical Guides in Oncology
SEOM clinical guidelines for anaplastic gliomas (2017)
Authors:
C. Balañá, M. Alonso, A. Hernandez, P. Perez-Segura, E. Pineda, A. Ramos, A. R. Sanchez, P. Teixidor, E. Verger, M. Benavides
Published in:
Clinical and Translational Oncology
|
Issue 1/2018
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Abstract
The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors.