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Published in: BMC Pregnancy and Childbirth 1/2020

01-12-2020 | Research article

Self-medication and knowledge among pregnant women attending primary healthcare services in Malang, Indonesia: a cross-sectional study

Authors: Rizka Novia Atmadani, Owen Nkoka, Sendi Lia Yunita, Yi-Hua Chen

Published in: BMC Pregnancy and Childbirth | Issue 1/2020

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Abstract

Background

Self-medication with over-the-counter (OTC) drugs is an important public health concern, especially in the vulnerable population of pregnant women due to potential risks to both the mother and fetus. Few studies have studied how factors, such as knowledge, affect self-medication. This study investigated self-medication and its associated factors among pregnant women attending healthcare services in Malang, Indonesia.

Methods

A cross-sectional study was conducted from July to September 2018 in five healthcare services. A self-administered questionnaire was used and the data were analyzed using multiple regression models.

Results

Of 333 female participants, 39 (11.7%) used OTC medication. Women with a higher level of knowledge of OTC medication were more likely to self-medicate—adjusted odds ratio (aOR) = 2.15, 95% confidence interval (CI) = 1.03–4.46. Compared with those with less knowledge, pregnant women with more correct knowledge of the possible risk of self-medication were less likely to self-medicate—aOR = 0.29; 95% CI = 0.14–0.60. The effect of a higher level of knowledge of OTC medication was significant among women who had middle school and lower education—aOR = 8.18; 95% CI = 1.70–39.35. The effect of correct knowledge on the possible risks of self-medication was significant only among women with high school and higher education—aOR = 0.17; 95% CI = 0.07–0.42.

Conclusion

Imparting specific knowledge of the potential risks of using non-prescribed medication during pregnancy may help pregnant women navigate and more safely manage their OTC use. We also suggest further collecting data from more healthcare services, such as hospitals, to obtain more findings generalizable to the Indonesian community.
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Literature
1.
go back to reference Lagoy CT, Joshi N, Cragan JD, Rasmussen SA. Report from the CDC: medication use during pregnancy and lactation: an urgent call for public health action. J Women's Health. 2005;14(2):104–9.CrossRef Lagoy CT, Joshi N, Cragan JD, Rasmussen SA. Report from the CDC: medication use during pregnancy and lactation: an urgent call for public health action. J Women's Health. 2005;14(2):104–9.CrossRef
2.
go back to reference Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mårdby AC, Moretti ME, Drozd M, Panchaud A, Hämeen-Anttila K, Rieutord A, et al. Medication use in pregnancy: A cross-sectional, multinational web-based study. BMJ Open. 2014;4(2):e004365.PubMedPubMedCentralCrossRef Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mårdby AC, Moretti ME, Drozd M, Panchaud A, Hämeen-Anttila K, Rieutord A, et al. Medication use in pregnancy: A cross-sectional, multinational web-based study. BMJ Open. 2014;4(2):e004365.PubMedPubMedCentralCrossRef
3.
go back to reference Bleek W, Asante-Darko NK. Illegal abortion in southern Ghana: methods, Motives and Consequences. Human Organization. 1986;45(4):333–44.CrossRef Bleek W, Asante-Darko NK. Illegal abortion in southern Ghana: methods, Motives and Consequences. Human Organization. 1986;45(4):333–44.CrossRef
4.
go back to reference Koren G, Florescu A, Costei AM, Boskovic R, Moretti ME. Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis. Ann Pharmacother. 2006;40(5):824–9.PubMedCrossRef Koren G, Florescu A, Costei AM, Boskovic R, Moretti ME. Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis. Ann Pharmacother. 2006;40(5):824–9.PubMedCrossRef
5.
go back to reference Binyam Kebede TGAG. Assessment of drug use among pregnant women in Addis Ababa; 2009. p. 462–8. Binyam Kebede TGAG. Assessment of drug use among pregnant women in Addis Ababa; 2009. p. 462–8.
6.
go back to reference Kessler DA, Pines WL. The federal regulation of prescription drug advertising and promotion. JAMA. 1990;264(18):2409–15.PubMedCrossRef Kessler DA, Pines WL. The federal regulation of prescription drug advertising and promotion. JAMA. 1990;264(18):2409–15.PubMedCrossRef
7.
go back to reference Yang T, Walker MC, Krewski D, Yang Q, Nimrod C, Garner P, Fraser W, Olatunbosun O, Wen SW. Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population. Pharmacoepidemiol Drug Saf. 2008;17(3):270–7.PubMedCrossRef Yang T, Walker MC, Krewski D, Yang Q, Nimrod C, Garner P, Fraser W, Olatunbosun O, Wen SW. Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population. Pharmacoepidemiol Drug Saf. 2008;17(3):270–7.PubMedCrossRef
8.
go back to reference Svensson T. Drug use during pregnancy in Sweden – assessed by the Prescribed Drug Register and the Medical Birth Register; 2011. p. 43–50. Svensson T. Drug use during pregnancy in Sweden – assessed by the Prescribed Drug Register and the Medical Birth Register; 2011. p. 43–50.
9.
go back to reference Hardon A, Van der Geest S, Hardon A. Self-medication in developing countries. J Soc Administr Pharmacy. 1990;7(4):199–204 2015(January 1990). Hardon A, Van der Geest S, Hardon A. Self-medication in developing countries. J Soc Administr Pharmacy. 1990;7(4):199–204 2015(January 1990).
10.
go back to reference Briggs GG, Freeman RK, Yaffe SJ. Drugs in pregnancy and lactation. 5th ed. Baltimore: Lippincott, Williams & Wilkins; 2003. Briggs GG, Freeman RK, Yaffe SJ. Drugs in pregnancy and lactation. 5th ed. Baltimore: Lippincott, Williams & Wilkins; 2003.
11.
go back to reference Robert E, Guibaud P. Maternal VALPROIC acid and congenital neural tube defects. Lancet. 1982;320(8304):937.CrossRef Robert E, Guibaud P. Maternal VALPROIC acid and congenital neural tube defects. Lancet. 1982;320(8304):937.CrossRef
12.
go back to reference Werler MM, Mitchell AA, Hernandez-Diaz S, Honein MA. Use of over-the-counter medications during pregnancy. Am J Obstet Gynecol. 2005;193(3):771–7.PubMedCrossRef Werler MM, Mitchell AA, Hernandez-Diaz S, Honein MA. Use of over-the-counter medications during pregnancy. Am J Obstet Gynecol. 2005;193(3):771–7.PubMedCrossRef
13.
go back to reference Verstappen GM, Smolders EJ, Munster JM, Aarnoudse JG, Hak E. Prevalence and predictors of over-the-counter medication use among pregnant women: A cross-sectional study in the Netherlands. BMC Public Health. 2013;13(1):185.PubMedPubMedCentralCrossRef Verstappen GM, Smolders EJ, Munster JM, Aarnoudse JG, Hak E. Prevalence and predictors of over-the-counter medication use among pregnant women: A cross-sectional study in the Netherlands. BMC Public Health. 2013;13(1):185.PubMedPubMedCentralCrossRef
14.
go back to reference Abduelkarem AR, Mustafa H. Use of over-the-counter medication among pregnant women in Sharjah, United Arab Emirates. J Pregnancy. 2017;2017:4503793.CrossRef Abduelkarem AR, Mustafa H. Use of over-the-counter medication among pregnant women in Sharjah, United Arab Emirates. J Pregnancy. 2017;2017:4503793.CrossRef
15.
go back to reference Cleary BJ, Butt H, Strawbridge JD, Gallagher PJ, Fahey T, Murphy DJ. Medication use in early pregnancy-prevalence and determinants of use in a prospective cohort of women. Pharmacoepidemiol Drug Saf. 2010;19(4):408–17.PubMed Cleary BJ, Butt H, Strawbridge JD, Gallagher PJ, Fahey T, Murphy DJ. Medication use in early pregnancy-prevalence and determinants of use in a prospective cohort of women. Pharmacoepidemiol Drug Saf. 2010;19(4):408–17.PubMed
16.
go back to reference Abeje G, Admasie C, Wasie B. Factors associated with self medication practice among pregnant mothers attending antenatal care at governmental health centers in Bahir Dar city administration, Northwest Ethiopia, a cross sectional study. Pan Afr Med J. 2015;20:276.PubMedPubMedCentralCrossRef Abeje G, Admasie C, Wasie B. Factors associated with self medication practice among pregnant mothers attending antenatal care at governmental health centers in Bahir Dar city administration, Northwest Ethiopia, a cross sectional study. Pan Afr Med J. 2015;20:276.PubMedPubMedCentralCrossRef
17.
go back to reference Bohio R, Brohi ZP, Bohio F. Utilization of over the counter medication among pregnant women; a cross-sectional study conducted at Isra University hospital, Hyderabad. J Pak Med Assoc. 2016;66(1):68–71.PubMed Bohio R, Brohi ZP, Bohio F. Utilization of over the counter medication among pregnant women; a cross-sectional study conducted at Isra University hospital, Hyderabad. J Pak Med Assoc. 2016;66(1):68–71.PubMed
18.
go back to reference Abasiubong F, Bassey EA, Udobang JA, Akinbami OS, Udoh SB, Idung AU. Self-medication: potential risks and hazards among pregnant women in Uyo, Nigeria. Pan Afr Med J. 2012;13:1–8. Abasiubong F, Bassey EA, Udobang JA, Akinbami OS, Udoh SB, Idung AU. Self-medication: potential risks and hazards among pregnant women in Uyo, Nigeria. Pan Afr Med J. 2012;13:1–8.
19.
go back to reference Beyene KGM, Beza SW. Self-medication practice and associated factors among pregnant women in Addis Ababa, Ethiopia. Trop Med Health. 2018;46(1):1–14.CrossRef Beyene KGM, Beza SW. Self-medication practice and associated factors among pregnant women in Addis Ababa, Ethiopia. Trop Med Health. 2018;46(1):1–14.CrossRef
20.
go back to reference Odalovic M, Vezmar Kovacevic S, Nordeng H, Ilic K, Sabo A, Tasic L. Predictors of the use of medications before and during pregnancy. Int J Clin Pharm. 2013;35(3):408–16.PubMedCrossRef Odalovic M, Vezmar Kovacevic S, Nordeng H, Ilic K, Sabo A, Tasic L. Predictors of the use of medications before and during pregnancy. Int J Clin Pharm. 2013;35(3):408–16.PubMedCrossRef
21.
go back to reference Ebrahimi H, Atashsokhan G, Amanpour F, Hamidzadeh A. Self-medication and its risk factors among women before and during pregnancy. Pan Afr Med J. 2017;27:1–8.CrossRef Ebrahimi H, Atashsokhan G, Amanpour F, Hamidzadeh A. Self-medication and its risk factors among women before and during pregnancy. Pan Afr Med J. 2017;27:1–8.CrossRef
22.
go back to reference Navaro M, Vezzosi L, Santagati G, Angelillo IF. Knowledge, attitudes, and practice regarding medication use in pregnant women in southern Italy. PLoS One. 2018;13(6):1–14.CrossRef Navaro M, Vezzosi L, Santagati G, Angelillo IF. Knowledge, attitudes, and practice regarding medication use in pregnant women in southern Italy. PLoS One. 2018;13(6):1–14.CrossRef
23.
go back to reference Indonesia Ministry of Health. Undang-undang obat keras:Staatsblad No.419;22. Jakarta: Indonesia Ministry of Health; 1949. Indonesia Ministry of Health. Undang-undang obat keras:Staatsblad No.419;22. Jakarta: Indonesia Ministry of Health; 1949.
24.
go back to reference Alfian SD, Sinuraya RK, Kautsar AP, Abdulah R. Consumer expectation on service quality provide by pharmacist in self medication practices and its associated factors in BANDUNG, Indonesia. Southeast Asian J Trop Med Public Health. 2016;47(6):1379–84.PubMed Alfian SD, Sinuraya RK, Kautsar AP, Abdulah R. Consumer expectation on service quality provide by pharmacist in self medication practices and its associated factors in BANDUNG, Indonesia. Southeast Asian J Trop Med Public Health. 2016;47(6):1379–84.PubMed
25.
go back to reference Badan Pusat S. Kabupaten Malang Dalam Angka 2017; 2017. Badan Pusat S. Kabupaten Malang Dalam Angka 2017; 2017.
26.
go back to reference Badan Pusat S. Statistik Kesejahteraan Rakyat Kota Malang 2017; 2017. Badan Pusat S. Statistik Kesejahteraan Rakyat Kota Malang 2017; 2017.
27.
go back to reference Beyene A, Getachew E, Doboch A, Poulos E, Abdurahman K, Alebachew M. Knowledge, attitude and practice of self medication among pharmacy students of rift Valley University, Abichu campus, Addis Ababa, Ethiopia. J Health Med Informat. 2017;8(269):2. Beyene A, Getachew E, Doboch A, Poulos E, Abdurahman K, Alebachew M. Knowledge, attitude and practice of self medication among pharmacy students of rift Valley University, Abichu campus, Addis Ababa, Ethiopia. J Health Med Informat. 2017;8(269):2.
28.
go back to reference Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. J Clin Epidemiol. 1993;46(12):1417–32.PubMedCrossRef Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. J Clin Epidemiol. 1993;46(12):1417–32.PubMedCrossRef
29.
go back to reference Isaac S, Michael WB. Handbook in research and evaluation. San Diego: Educational and Industrial Testing Services; 1995. Isaac S, Michael WB. Handbook in research and evaluation. San Diego: Educational and Industrial Testing Services; 1995.
30.
go back to reference Sharma D, Gurung D, Kafle R, Singh S. Knowledge and practice on over-the-counter drugs among adults of age group 20 and above residing in Chapapani-12, Pokhara, Kaski, Nepal. Int J Sci Rep. 2017;33(3):79–86.CrossRef Sharma D, Gurung D, Kafle R, Singh S. Knowledge and practice on over-the-counter drugs among adults of age group 20 and above residing in Chapapani-12, Pokhara, Kaski, Nepal. Int J Sci Rep. 2017;33(3):79–86.CrossRef
31.
go back to reference Nkoka O, Chuang T-W, Chen Y-H. Multilevel analysis of factors associated with treatment-seeking behaviors among caregivers with febrile children in Malawi; 2019.CrossRef Nkoka O, Chuang T-W, Chen Y-H. Multilevel analysis of factors associated with treatment-seeking behaviors among caregivers with febrile children in Malawi; 2019.CrossRef
32.
go back to reference Nordeng H, Koren G, Einarson A. Pregnant women's beliefs about medications - a study among 866 Norwegian women. Ann Pharmacother. 2010;44(9):1478–84.PubMedCrossRef Nordeng H, Koren G, Einarson A. Pregnant women's beliefs about medications - a study among 866 Norwegian women. Ann Pharmacother. 2010;44(9):1478–84.PubMedCrossRef
33.
go back to reference Zaki NM, Albarraq AA. Use, attitudes and knowledge of medications among pregnant women: a Saudi study. Saudi Pharm J. 2014;22(5):419–28.PubMedCrossRef Zaki NM, Albarraq AA. Use, attitudes and knowledge of medications among pregnant women: a Saudi study. Saudi Pharm J. 2014;22(5):419–28.PubMedCrossRef
34.
go back to reference Ceulemans M, Van Calsteren K, Allegaert K, Foulon V. Beliefs about medicines and information needs among pregnant women visiting a tertiary hospital in Belgium. Eur J Clin Pharmacol. 2019;75(7):995–1003.PubMedCrossRef Ceulemans M, Van Calsteren K, Allegaert K, Foulon V. Beliefs about medicines and information needs among pregnant women visiting a tertiary hospital in Belgium. Eur J Clin Pharmacol. 2019;75(7):995–1003.PubMedCrossRef
35.
go back to reference Katz MH. Multivariable analysis: a practical guide for clinicians and public health researchers: Cambridge university press; 2011.CrossRef Katz MH. Multivariable analysis: a practical guide for clinicians and public health researchers: Cambridge university press; 2011.CrossRef
36.
go back to reference Nkoka O, Chuang TW, Chen YH. Association between timing and number of antenatal care visits on uptake of intermittent preventive treatment for malaria during pregnancy among Malawian women. Malar J. 2018;17(1):1–11.CrossRef Nkoka O, Chuang TW, Chen YH. Association between timing and number of antenatal care visits on uptake of intermittent preventive treatment for malaria during pregnancy among Malawian women. Malar J. 2018;17(1):1–11.CrossRef
37.
go back to reference Okandeji-Barry RO, Otovwe A, Uju OS. Pharmaceutical Knowledge , Attitude and Use of Non-Prescription Drugs Among Pregnant Women in Okwe General Hospital Asaba Delta State ,Nigeria. Eur J Pharm Med Res. 2016;3(11):101–10. Okandeji-Barry RO, Otovwe A, Uju OS. Pharmaceutical Knowledge , Attitude and Use of Non-Prescription Drugs Among Pregnant Women in Okwe General Hospital Asaba Delta State ,Nigeria. Eur J Pharm Med Res. 2016;3(11):101–10.
39.
go back to reference Selvaraj K, Kumar SG, Ramalingam A. Prevalence of self-medication practices and its associated factors in urban Puducherry, India. Perspect Clin Res. 2014;5(1):32.PubMedPubMedCentralCrossRef Selvaraj K, Kumar SG, Ramalingam A. Prevalence of self-medication practices and its associated factors in urban Puducherry, India. Perspect Clin Res. 2014;5(1):32.PubMedPubMedCentralCrossRef
40.
go back to reference Kassaw C, Wabe NT. Pregnant women and non-steroidal anti-inflammatory drugs: knowledge, perception and drug consumption pattern during pregnancy in Ethiopia. N Am J Med Sci. 2012;4(2):72.PubMedPubMedCentralCrossRef Kassaw C, Wabe NT. Pregnant women and non-steroidal anti-inflammatory drugs: knowledge, perception and drug consumption pattern during pregnancy in Ethiopia. N Am J Med Sci. 2012;4(2):72.PubMedPubMedCentralCrossRef
41.
go back to reference Awad AI, Eltayeb IB, Capps PA. Self-medication practices in Khartoum state, Sudan. Eur J Clin Pharmacol. 2006;62(4):317–24.PubMedCrossRef Awad AI, Eltayeb IB, Capps PA. Self-medication practices in Khartoum state, Sudan. Eur J Clin Pharmacol. 2006;62(4):317–24.PubMedCrossRef
42.
go back to reference Devkota R, Khan GM, Alam K, Sapkota B, Devkota D. Impacts of counseling on knowledge, attitude and practice of medication use during pregnancy. BMC Pregnancy Childbirth. 2017;17(1):1–7.CrossRef Devkota R, Khan GM, Alam K, Sapkota B, Devkota D. Impacts of counseling on knowledge, attitude and practice of medication use during pregnancy. BMC Pregnancy Childbirth. 2017;17(1):1–7.CrossRef
43.
go back to reference Marwa KJ, Njalika A, Ruganuza D, Katabalo D, Kamugisha E. Self-medication among pregnant women attending antenatal clinic at Makongoro health Centre in Mwanza, Tanzania: a challenge to health systems. BMC Pregnancy Childbirth. 2018;18(1):1–9.CrossRef Marwa KJ, Njalika A, Ruganuza D, Katabalo D, Kamugisha E. Self-medication among pregnant women attending antenatal clinic at Makongoro health Centre in Mwanza, Tanzania: a challenge to health systems. BMC Pregnancy Childbirth. 2018;18(1):1–9.CrossRef
44.
go back to reference Lei X, Jiang H, Liu C, Ferrier A, Mugavin J. Self-medication practice and associated factors among residents in Wuhan, China. Int J Environ Res Public Health. 2018;15(1):68.PubMedCentralCrossRef Lei X, Jiang H, Liu C, Ferrier A, Mugavin J. Self-medication practice and associated factors among residents in Wuhan, China. Int J Environ Res Public Health. 2018;15(1):68.PubMedCentralCrossRef
Metadata
Title
Self-medication and knowledge among pregnant women attending primary healthcare services in Malang, Indonesia: a cross-sectional study
Authors
Rizka Novia Atmadani
Owen Nkoka
Sendi Lia Yunita
Yi-Hua Chen
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2020
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-020-2736-2

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