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Archives of Gynecology and Obstetrics

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01-04-2012 | Maternal-Fetal Medicine

Selective and non-selective intrauterine growth restriction in twin pregnancies: high-risk factors and perinatal outcome

Authors: Yu Gao, Zhiming He, Yanmin Luo, Hongyu Sun, Linhuan Huang, Manchao Li, Yi Zhou, Baojiang Chen, Qun Fang

Published in: Archives of Gynecology and Obstetrics | Issue 4/2012

Abstract

Purpose

To evaluate the high-risk factors and perinatal outcome in selective intrauterine growth restriction (sIUGR) and non-selective IUGR (non-sIUGR) in twins.

Methods

In total, 336 pairs of twins were enrolled from December 2003 to 2009. According to the birth weight, 295 pairs of twins were divided into sIUGR, non-sIUGR and normal growth groups. Maternal characteristics, complications, chorionicity, zygosity and perinatal outcomes were analyzed among the three groups.

Results

The overall IUGR incidence (including sIUGR and non-sIUGR) in twin pregnancies was 23.2%. The sIUGR incidence was ten times greater than that of non-sIUGR. Monochorionicity and monozygosity were risk factors for overall IUGR, especially for the sIUGR (P < 0.01). Pre-eclampsia was more common in sIUGR than in the normal growth group (P < 0.05). Both the sIUGR and non-sIUGR groups had more intrauterine fetal death and neonatal death than the normal growth group (P < 0.01). The sIUGR group had more brain injury than the normal growth group (P < 0.01).

Conclusion

Monochorionicity, monozygosity, pre-eclampsia were high-risk factors for IUGR in twins. Perinatal death was more prevalent in the non-sIUGR group, and neonatal brain damage was more prevalent in the sIUGR group.

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Title: Selective and non-selective intrauterine growth restriction in twin pregnancies: high-risk factors and perinatal outcome
Authors: Yu Gao
Zhiming He
Yanmin Luo
Hongyu Sun
Linhuan Huang
Manchao Li
Yi Zhou
Baojiang Chen
Qun Fang
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 4/2012
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-011-2119-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Selective and non-selective intrauterine growth restriction in twin pregnancies: high-risk factors and perinatal outcome

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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