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Published in: BMC Pregnancy and Childbirth 1/2024

Open Access 01-12-2024 | Sectio Caesarea | Case Report

Spontaneous regression of a giant uterine leiomyoma after delivery: a case report and literature review

Authors: Lifang Zhu-ge, Qiaoli Bei, Weiping Pan, Xiaojun Ni

Published in: BMC Pregnancy and Childbirth | Issue 1/2024

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Abstract

Background

Uterine leiomyomas are hormone-dependent benign tumors and often begin to shrink after menopause due to the reduction in ovarian steroids. The influence of pregnancy on uterine leiomyomas size remains unclear. Here, we present a case of spontaneous regression of a giant uterine leiomyoma after delivery.

Case presentation

A 40-year-old woman presented with multiple uterine leiomyomas, one of which is a giant uterine leiomyomas (approximately 8 cm in diameter) that gradually shrinked after delivery. At over two months postpartum, the large myometrial leiomyoma had transformed into a submucosal leiomyoma, and over 3 years postpartum, both the submucosal leiomyoma and multiple intramural leiomyomas completely regressed.

Conclusion

Spontaneous regression of a giant uterine leiomyom is rare after delivery. Considering uterine leiomyoma regression until over 3 year postpartum,we need to observe the regression of uterine fibroid for a longer time postpartum in the absence of fibroid related complications. In addition, it will provide new insights for treatment options of uterine leiomyomas in the future.
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Metadata
Title
Spontaneous regression of a giant uterine leiomyoma after delivery: a case report and literature review
Authors
Lifang Zhu-ge
Qiaoli Bei
Weiping Pan
Xiaojun Ni
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2024
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-024-06324-2

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