Published in:
Open Access
01-02-2011 | Poster presentation
Seasonal vitamin D variability and its effects on the innate immune response during human endotoxemia
Authors:
MJ Van den Berg, M Kox, AJ Van der Ven, JP Wielders, P Pickkers
Published in:
Critical Care
|
Special Issue 1/2011
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Excerpt
In the past several years, an important immuno-modulatory role for vitamin D has been identified. At high latitudes, seasonal vitamin D deficiency is common due to due to low UV-B radiation exposure, which is necessary for the synthesis of vitamin D. In this retrospective study we investigated whether vitamin D levels are subject to seasonal variation and whether plasma levels of vitamin D correlate with the extent of the innate immune response during human endotoxemia. …