Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 10/2015

01-10-2015 | Otology

Seasonal trends in tinnitus symptomatology: evidence from Internet search engine query data

Authors: David T. Plante, David G. Ingram

Published in: European Archives of Oto-Rhino-Laryngology | Issue 10/2015

Login to get access

Abstract

The primary aim of this study was to test the hypothesis that the symptom of tinnitus demonstrates a seasonal pattern with worsening in the winter relative to the summer using Internet search engine query data. Normalized search volume for the term ‘tinnitus’ from January 2004 through December 2013 was retrieved from Google Trends. Seasonal effects were evaluated using cosinor regression models. Primary countries of interest were the United States and Australia. Secondary exploratory analyses were also performed using data from Germany, the United Kingdom, Canada, Sweden, and Switzerland. Significant seasonal effects for ‘tinnitus’ search queries were found in the United States and Australia (p < 0.00001 for both countries), with peaks in the winter and troughs in the summer. Secondary analyses demonstrated similarly significant seasonal effects for Germany (p < 0.00001), Canada (p < 0.00001), and Sweden (p = 0.0008), again with increased search volume in the winter relative to the summer. Our findings indicate that there are significant seasonal trends for Internet search queries for tinnitus, with a zenith in winter months. Further research is indicated to determine the biological mechanisms underlying these findings, as they may provide insights into the pathophysiology of this common and debilitating medical symptom.
Literature
3.
go back to reference Izuhara K, Wada K, Nakamura K, Tamai Y, Tsuji M, Ito Y, Nagata C (2013) Association between tinnitus and sleep disorders in the general Japanese population. Ann Otol Rhinol Laryngol 122(11):701–706CrossRefPubMed Izuhara K, Wada K, Nakamura K, Tamai Y, Tsuji M, Ito Y, Nagata C (2013) Association between tinnitus and sleep disorders in the general Japanese population. Ann Otol Rhinol Laryngol 122(11):701–706CrossRefPubMed
8.
go back to reference Derebery MJ, Berliner KI (1998) Allergy for the otologist. External canal to inner ear. Otolaryngol Clin North Am 31(1):157–173CrossRefPubMed Derebery MJ, Berliner KI (1998) Allergy for the otologist. External canal to inner ear. Otolaryngol Clin North Am 31(1):157–173CrossRefPubMed
11.
go back to reference Atkinson M (1947) Tinnitus aurium; some considerations concerning its origin and treatment. Arch Otolaryngol 45(1):68–76CrossRefPubMed Atkinson M (1947) Tinnitus aurium; some considerations concerning its origin and treatment. Arch Otolaryngol 45(1):68–76CrossRefPubMed
13.
go back to reference Bilecki MM, Bernarde GE, Mezzalira R, Maestri JE, Cardoso JM, Avila FG (2005) Seasonality in vestibular disorders. Int Tinnitus J 11(2):185–188PubMed Bilecki MM, Bernarde GE, Mezzalira R, Maestri JE, Cardoso JM, Avila FG (2005) Seasonality in vestibular disorders. Int Tinnitus J 11(2):185–188PubMed
14.
go back to reference Inaba R, Kurokawa J, Mirbod SM (2009) Comparison of subjective symptoms and cold prevention measures in winter between traffic control workers and construction workers in Japan. Ind Health 47(3):283–291CrossRefPubMed Inaba R, Kurokawa J, Mirbod SM (2009) Comparison of subjective symptoms and cold prevention measures in winter between traffic control workers and construction workers in Japan. Ind Health 47(3):283–291CrossRefPubMed
15.
go back to reference Inaba R, Mirbod SM (2010) Subjective musculoskeletal symptoms in winter and summer among indoor working construction electricians. Ind Health 48(1):29–37CrossRefPubMed Inaba R, Mirbod SM (2010) Subjective musculoskeletal symptoms in winter and summer among indoor working construction electricians. Ind Health 48(1):29–37CrossRefPubMed
17.
go back to reference Eysenbach G, Kohler C (2003) What is the prevalence of health-related searches on the World Wide Web? Qualitative and quantitative analysis of search engine queries on the Internet. AMIA Annu Symp Proc, pp 225–229 Eysenbach G, Kohler C (2003) What is the prevalence of health-related searches on the World Wide Web? Qualitative and quantitative analysis of search engine queries on the Internet. AMIA Annu Symp Proc, pp 225–229
18.
25.
go back to reference Barnett A, Baker P, Dobson AJ (2012) Analysing seasonal data. R Journal 4(1):5–10 Barnett A, Baker P, Dobson AJ (2012) Analysing seasonal data. R Journal 4(1):5–10
28.
go back to reference Ahmad N, Seidman M (2004) Tinnitus in the older adult: epidemiology, pathophysiology and treatment options. Drugs Aging 21(5):297–305CrossRefPubMed Ahmad N, Seidman M (2004) Tinnitus in the older adult: epidemiology, pathophysiology and treatment options. Drugs Aging 21(5):297–305CrossRefPubMed
29.
30.
go back to reference Brummett RE (1993) Ototoxic liability of erythromycin and analogues. Otolaryngol Clin North Am 26(5):811–819PubMed Brummett RE (1993) Ototoxic liability of erythromycin and analogues. Otolaryngol Clin North Am 26(5):811–819PubMed
31.
go back to reference Adriaenssens N, Coenen S, Versporten A, Muller A, Minalu G, Faes C, Vankerckhoven V, Aerts M, Hens N, Molenberghs G, Goossens H, Group EP (2011) European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997–2009). J Antimicrob Chemother 66 Suppl 6:vi37–vi45. doi:10.1093/jac/dkr456 PubMed Adriaenssens N, Coenen S, Versporten A, Muller A, Minalu G, Faes C, Vankerckhoven V, Aerts M, Hens N, Molenberghs G, Goossens H, Group EP (2011) European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997–2009). J Antimicrob Chemother 66 Suppl 6:vi37–vi45. doi:10.​1093/​jac/​dkr456 PubMed
35.
go back to reference Tahera Y, Meltser I, Johansson P, Bian Z, Stierna P, Hansson AC, Canlon B (2006) NF-kappaB mediated glucocorticoid response in the inner ear after acoustic trauma. J Neurosci Res 83(6):1066–1076. doi:10.1002/jnr.20795 CrossRefPubMed Tahera Y, Meltser I, Johansson P, Bian Z, Stierna P, Hansson AC, Canlon B (2006) NF-kappaB mediated glucocorticoid response in the inner ear after acoustic trauma. J Neurosci Res 83(6):1066–1076. doi:10.​1002/​jnr.​20795 CrossRefPubMed
36.
go back to reference Job A, Raynal M, Kossowski M (2007) Susceptibility to tinnitus revealed at 2 kHz range by bilateral lower DPOAEs in normal hearing subjects with noise exposure. Audiol Neurootol 12(3):137–144. doi:10.1159/000099025 CrossRefPubMed Job A, Raynal M, Kossowski M (2007) Susceptibility to tinnitus revealed at 2 kHz range by bilateral lower DPOAEs in normal hearing subjects with noise exposure. Audiol Neurootol 12(3):137–144. doi:10.​1159/​000099025 CrossRefPubMed
40.
go back to reference Snihur AW, Hampson E (2012) Click-evoked otoacoustic emissions: response amplitude is associated with circulating testosterone levels in men. Behav Neurosci 126(2):325–331. doi:10.1037/a0027193 CrossRefPubMed Snihur AW, Hampson E (2012) Click-evoked otoacoustic emissions: response amplitude is associated with circulating testosterone levels in men. Behav Neurosci 126(2):325–331. doi:10.​1037/​a0027193 CrossRefPubMed
43.
go back to reference Spindelegger C, Stein P, Wadsak W, Fink M, Mitterhauser M, Moser U, Savli M, Mien LK, Akimova E, Hahn A, Willeit M, Kletter K, Kasper S, Lanzenberger R (2012) Light-dependent alteration of serotonin-1A receptor binding in cortical and subcortical limbic regions in the human brain. World J Biol Psychiatry 13(6):413–422. doi:10.3109/15622975.2011.630405 CrossRefPubMed Spindelegger C, Stein P, Wadsak W, Fink M, Mitterhauser M, Moser U, Savli M, Mien LK, Akimova E, Hahn A, Willeit M, Kletter K, Kasper S, Lanzenberger R (2012) Light-dependent alteration of serotonin-1A receptor binding in cortical and subcortical limbic regions in the human brain. World J Biol Psychiatry 13(6):413–422. doi:10.​3109/​15622975.​2011.​630405 CrossRefPubMed
46.
go back to reference Urry HL, van Reekum CM, Johnstone T, Kalin NH, Thurow ME, Schaefer HS, Jackson CA, Frye CJ, Greischar LL, Alexander AL, Davidson RJ (2006) Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. J Neurosci 26(16):4415–4425. doi:10.1523/JNEUROSCI.3215-05.2006 CrossRefPubMed Urry HL, van Reekum CM, Johnstone T, Kalin NH, Thurow ME, Schaefer HS, Jackson CA, Frye CJ, Greischar LL, Alexander AL, Davidson RJ (2006) Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. J Neurosci 26(16):4415–4425. doi:10.​1523/​JNEUROSCI.​3215-05.​2006 CrossRefPubMed
47.
go back to reference comScore Releases January 2013 U.S. Search Engine Rankings (2013) Accessed 26 April 2013 comScore Releases January 2013 U.S. Search Engine Rankings (2013) Accessed 26 April 2013
Metadata
Title
Seasonal trends in tinnitus symptomatology: evidence from Internet search engine query data
Authors
David T. Plante
David G. Ingram
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 10/2015
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-014-3287-9

Other articles of this Issue 10/2015

European Archives of Oto-Rhino-Laryngology 10/2015 Go to the issue