Published in:
Open Access
01-02-2011 | Poster presentation
Searching for mechanisms that matter in septic acute kidney injury: an experimental study
Authors:
J Benes, J Chvojka, R Sykora, J Radej, A Krouzecky, I Novak, M Matejovic
Published in:
Critical Care
|
Special Issue 1/2011
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Excerpt
Both hemodynamic and nonhemodynamic factors are implicated in the pathogenesis of sepsis-induced acute kidney injury (SAKI). However, despite similar septic insult, not all patients develop SAKI. The reasons for the difference in sensitivity to AKI are unknown. Therefore, we sought to analyze dynamic changes in renal hemodynamic and non-hemodynamic responses to sepsis in animals who developed AKI and those who do not. …