Skip to main content
Top
Published in: Current Pulmonology Reports 2/2017

01-06-2017 | Sleeping and Breathing (T Lee-Chiong, Section Editor)

Screening Programs for Obstructive Sleep Apnea

Authors: Virginia S. de Los Reyes, Cecilia A. Jimeno, Vincent Anthony S. Tang, Patricia Marie M. Lusica

Published in: Current Pulmonology Reports | Issue 2/2017

Login to get access

Abstract

Purpose of the Review

The aim of this article is to describe the literature on the rationale, methods, and outcomes of screening programs for obstructive sleep apnea (OSA).

Recent Findings

The evidence does not support screening for OSA in the general population. Instead, targeted case finding is advised among the following high-risk groups: patients with obesity, congestive heart failure, atrial fibrillation, treatment refractory hypertension, type 2 diabetes, stroke, nocturnal dysrhythmias, and pulmonary hypertension. However, the method of screening remains unclear with some studies suggesting the use of questionnaires to identify risk for OSA prior to polysomnography (PSG), while others recommend 2-step screening involving questionnaires and portable monitors. Commercial motor vehicle (CMV) drivers should undergo universal screening.

Summary

There is a clear rationale for screening, and target populations for screening have been identified. However, the method of screening is not yet clear. Randomized trials should be done to compare the outcomes of screening versus no screening for OSA among the high-risk populations.
Literature
3.
go back to reference Young T, Palta M, Dempsey J, et al. Burden of sleep apnea: rationale, design, and major findings of the Wisconsin Sleep Cohort study. WMJ. 2009;108(5):246–9.PubMedPubMedCentral Young T, Palta M, Dempsey J, et al. Burden of sleep apnea: rationale, design, and major findings of the Wisconsin Sleep Cohort study. WMJ. 2009;108(5):246–9.PubMedPubMedCentral
4.
go back to reference Coughlin SR, Mawdsley L, Mugarza JA, Calverley PMA, Wilding JPH. Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J. 2004;25:735–41.CrossRef Coughlin SR, Mawdsley L, Mugarza JA, Calverley PMA, Wilding JPH. Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J. 2004;25:735–41.CrossRef
5.
go back to reference Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. JAMA. 2000;283:1829–36.CrossRef Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. JAMA. 2000;283:1829–36.CrossRef
6.
go back to reference Young T, Peppard P, Palta M, Hla KM, Finn L, Morgan B, et al. Population-based study of sleep-disordered breathing as a risk factor for hypertension. Arch Intern Med. 1997;157:1746–52.CrossRef Young T, Peppard P, Palta M, Hla KM, Finn L, Morgan B, et al. Population-based study of sleep-disordered breathing as a risk factor for hypertension. Arch Intern Med. 1997;157:1746–52.CrossRef
8.
go back to reference Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med. 2005;353:2034–41.CrossRef Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med. 2005;353:2034–41.CrossRef
10.
go back to reference Doonan RJ, Scheffler P, Lalli M, Kimoff RJ, Petridou ET, Daskalopoulos ME, et al. Increased arterial stiffness in obstructive sleep apnea: a systematic review. Hypertens Res. 2011;34:23–32.CrossRef Doonan RJ, Scheffler P, Lalli M, Kimoff RJ, Petridou ET, Daskalopoulos ME, et al. Increased arterial stiffness in obstructive sleep apnea: a systematic review. Hypertens Res. 2011;34:23–32.CrossRef
11.
go back to reference Hoffstein V, Mateika S. Cardiac-arrhythmias, snoring, and sleep-apnea. Chest. 1994;106:466–71.CrossRef Hoffstein V, Mateika S. Cardiac-arrhythmias, snoring, and sleep-apnea. Chest. 1994;106:466–71.CrossRef
15.
go back to reference Liao P, Yegneswaran B, Vairavanathan S, Ziberman P, Chung F, et al. Postoperative complications in patients with obstructive sleep apnea: a retrospective matched cohort study. Canadian J Anaesth. 2009;56:819–28. doi:10.1007/s12630-009-9190-y.CrossRef Liao P, Yegneswaran B, Vairavanathan S, Ziberman P, Chung F, et al. Postoperative complications in patients with obstructive sleep apnea: a retrospective matched cohort study. Canadian J Anaesth. 2009;56:819–28. doi:10.​1007/​s12630-009-9190-y.CrossRef
18.
go back to reference Screening for obstructive sleep apnea in adults: an evidence review for the U.S. Preventive Services Task Force AHRQ Publication No. 14–05216-EF-1 June 2016 Screening for obstructive sleep apnea in adults: an evidence review for the U.S. Preventive Services Task Force AHRQ Publication No. 14–05216-EF-1 June 2016
19.
go back to reference Horstmann S, Hess CW, Bassetti C, et al. Sleepiness-related accidents in sleep apnea patients. Sleep. 2000;23(3):383–9.CrossRef Horstmann S, Hess CW, Bassetti C, et al. Sleepiness-related accidents in sleep apnea patients. Sleep. 2000;23(3):383–9.CrossRef
20.
go back to reference Quan SF, Wright R, Baldwin CM, et al. Obstructive sleep apnea-hypopnea and neurocognitive functioning in the sleep heart health study. Sleep Med. 2006;6:498–507.CrossRef Quan SF, Wright R, Baldwin CM, et al. Obstructive sleep apnea-hypopnea and neurocognitive functioning in the sleep heart health study. Sleep Med. 2006;6:498–507.CrossRef
21.
go back to reference Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002;165(9):1217–39.CrossRef Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002;165(9):1217–39.CrossRef
22.
go back to reference Victor LD. Obstructive sleep apnea. Am Fam Physician. 1999;60:2279–86.PubMed Victor LD. Obstructive sleep apnea. Am Fam Physician. 1999;60:2279–86.PubMed
24.
go back to reference Kushida CA, Littner MR, Hirshkowitz M, Morgenthaler TI, Alessi CA, Bailey D, Boehlecke B, et al. Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders. Sleep. 2006;29:375–80.CrossRef Kushida CA, Littner MR, Hirshkowitz M, Morgenthaler TI, Alessi CA, Bailey D, Boehlecke B, et al. Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders. Sleep. 2006;29:375–80.CrossRef
25.
go back to reference Montesi SB, Edwards BA, Malhotra A, Bakker JP. The effect of continuous positive airway pressure treatment on blood pressure: a systematic review and meta-analysis of randomized controlled trials. JClin Sleep Med. 2012;8(5):587–96. doi:10.5664/jcsm.2170.CrossRef Montesi SB, Edwards BA, Malhotra A, Bakker JP. The effect of continuous positive airway pressure treatment on blood pressure: a systematic review and meta-analysis of randomized controlled trials. JClin Sleep Med. 2012;8(5):587–96. doi:10.​5664/​jcsm.​2170.CrossRef
27.
go back to reference Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–53. doi:10.1016/S0140-6736(05)71141-7.CrossRefPubMed Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–53. doi:10.​1016/​S0140-6736(05)71141-7.CrossRefPubMed
28.
go back to reference Ellen RL, Marshall SC, Palayew M, Molnar FJ, Wilson KG, Man-Son-Hing M. Systematic review of motor vehicle crash risk in persons with sleep apnea. J Clin Sleep Med. 2006;2:193–200.PubMed Ellen RL, Marshall SC, Palayew M, Molnar FJ, Wilson KG, Man-Son-Hing M. Systematic review of motor vehicle crash risk in persons with sleep apnea. J Clin Sleep Med. 2006;2:193–200.PubMed
29.
go back to reference Tanaka S, Shima M. Assessment of screening tests for sleep apnea syndrome in the workplace. J Occup Health. 2010;52:99–105.CrossRef Tanaka S, Shima M. Assessment of screening tests for sleep apnea syndrome in the workplace. J Occup Health. 2010;52:99–105.CrossRef
30.
go back to reference Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14:540–3.CrossRef Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14:540–3.CrossRef
33.
go back to reference Chung F, Yegneswaran B, Liao P, Chung SA, Vairavanathan S, Islam S, et al. Validation of the Berlin questionnaire and American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patients. Anesthesiology. 2008;108:822–30. doi:10.1097/ALN.0b013e31816d91b5.CrossRefPubMed Chung F, Yegneswaran B, Liao P, Chung SA, Vairavanathan S, Islam S, et al. Validation of the Berlin questionnaire and American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patients. Anesthesiology. 2008;108:822–30. doi:10.​1097/​ALN.​0b013e31816d91b5​.CrossRefPubMed
34.
go back to reference Silva GE, Vana KD, Goodwin JL, Sherrill DL, Quan SF. Identification of patients with sleep disordered breathing: comparing the four-variable screening tool, STOP, STOP-Bang, and Epworth Sleepiness Scales. J Clin Sleep Med. 2011;7:467–72. doi:10.5664/JCSM.1308.CrossRefPubMedPubMedCentral Silva GE, Vana KD, Goodwin JL, Sherrill DL, Quan SF. Identification of patients with sleep disordered breathing: comparing the four-variable screening tool, STOP, STOP-Bang, and Epworth Sleepiness Scales. J Clin Sleep Med. 2011;7:467–72. doi:10.​5664/​JCSM.​1308.CrossRefPubMedPubMedCentral
35.
go back to reference •• Hrubos-Strom H, Randby A, Namtvedt SK, et al. A Norwegian population-based study on the risk and prevalence of obstructive sleep apnea. The Akershus Sleep Apnea Project (ASAP). J Sleep Res. 2011;201:162–70. doi:10.1111/j.1365-2869.2010.00861.x. The conclusion of this study is that the screening properties of the Berlin Questionnaire are suboptimal in a large sample of randomly selected respondents from the general Norwegian population CrossRef •• Hrubos-Strom H, Randby A, Namtvedt SK, et al. A Norwegian population-based study on the risk and prevalence of obstructive sleep apnea. The Akershus Sleep Apnea Project (ASAP). J Sleep Res. 2011;201:162–70. doi:10.​1111/​j.​1365-2869.​2010.​00861.​x. The conclusion of this study is that the screening properties of the Berlin Questionnaire are suboptimal in a large sample of randomly selected respondents from the general Norwegian population CrossRef
36.
go back to reference • Burgess KR, Havryk A, Newton S, Tsai WH, Whitelaw WA. Targeted case finding for OSA within the primary care setting. J Clin Sleep Med. 2013;9(7):681–6. doi:10.5664/jcsm.2838. In this community screening of 1157 individuals, high-risk patients that may be targeted for screening for OSA are those with BMI > 30, type 2 diabetes, treated hypertension, and ischemic heart disease because of the high prevalence of OSA in this population CrossRefPubMedPubMedCentral • Burgess KR, Havryk A, Newton S, Tsai WH, Whitelaw WA. Targeted case finding for OSA within the primary care setting. J Clin Sleep Med. 2013;9(7):681–6. doi:10.​5664/​jcsm.​2838. In this community screening of 1157 individuals, high-risk patients that may be targeted for screening for OSA are those with BMI > 30, type 2 diabetes, treated hypertension, and ischemic heart disease because of the high prevalence of OSA in this population CrossRefPubMedPubMedCentral
37.
go back to reference Gurubhagavatula I, Fields BG, Morales CR, et al. Screening for severe obstructive sleep apnea syndrome in hypertensive outpatients. J Clin Hypertens (Greenwich). 2013;15(4):279–88. doi:10.1111/jch.12073.CrossRef Gurubhagavatula I, Fields BG, Morales CR, et al. Screening for severe obstructive sleep apnea syndrome in hypertensive outpatients. J Clin Hypertens (Greenwich). 2013;15(4):279–88. doi:10.​1111/​jch.​12073.CrossRef
38.
go back to reference Westlake K, Plihalova A, Pretl M, Lattova Z, Polak J. Screening for obstructive sleep apnea syndrome in patients with type 2 diabetes mellitus: a prospective study on sensitivity of Berlin and STOP-Bang questionnaires. Sleep Med. 2016;26:71–6. doi:10.1016/j.sleep.2016.07.009.CrossRefPubMed Westlake K, Plihalova A, Pretl M, Lattova Z, Polak J. Screening for obstructive sleep apnea syndrome in patients with type 2 diabetes mellitus: a prospective study on sensitivity of Berlin and STOP-Bang questionnaires. Sleep Med. 2016;26:71–6. doi:10.​1016/​j.​sleep.​2016.​07.​009.CrossRefPubMed
40.
go back to reference • Platt AB, Wick LC, Hurley S, Soto-Calderon H, Wieland W, Staley B, Masilin G, et al. Hits and misses: screening commercial drivers for obstructive sleep apnea using guidelines recommended by a joint task force. JOEM. 2013;55(9):1035–40. doi:10.1097/JOM.0b013e318298fb0e. This study showed that the high burden of OSA combined with the good performance of the screening tools supports universal screening of all commercial drivers CrossRefPubMed • Platt AB, Wick LC, Hurley S, Soto-Calderon H, Wieland W, Staley B, Masilin G, et al. Hits and misses: screening commercial drivers for obstructive sleep apnea using guidelines recommended by a joint task force. JOEM. 2013;55(9):1035–40. doi:10.​1097/​JOM.​0b013e318298fb0e​. This study showed that the high burden of OSA combined with the good performance of the screening tools supports universal screening of all commercial drivers CrossRefPubMed
41.
go back to reference Hoffman B, Wingenbach DD, Kagey AN, Schaneman JL, Kasper D. The long-term health plan and disability cost benefit of obstructive sleep apnea treatment in a commercial motor vehicle driver population. J Occup Environ Med. 2010;52:473–7. doi:10.1097/JOM.0b013e3181dbc8ab.CrossRefPubMed Hoffman B, Wingenbach DD, Kagey AN, Schaneman JL, Kasper D. The long-term health plan and disability cost benefit of obstructive sleep apnea treatment in a commercial motor vehicle driver population. J Occup Environ Med. 2010;52:473–7. doi:10.​1097/​JOM.​0b013e3181dbc8ab​.CrossRefPubMed
42.
go back to reference Bahammam A, Delaive K, Ronald J, Manfreda J, Roos L, Kryger MH. Health care utilization in males with obstructive sleep apnea syndrome two years after diagnosis and treatment. Sleep. 1999;22:740–7.CrossRef Bahammam A, Delaive K, Ronald J, Manfreda J, Roos L, Kryger MH. Health care utilization in males with obstructive sleep apnea syndrome two years after diagnosis and treatment. Sleep. 1999;22:740–7.CrossRef
45.
go back to reference Mold JW, Quattlebaum C, Schinnerer E, et al. Identification by primary care clinicians of patients with obstructive sleep apnea: a practice-based research network (PBRN) study. J Am Board Fam Med. 2011;2:138–45. doi:10.3122/jabfm.2011.02.100095.CrossRef Mold JW, Quattlebaum C, Schinnerer E, et al. Identification by primary care clinicians of patients with obstructive sleep apnea: a practice-based research network (PBRN) study. J Am Board Fam Med. 2011;2:138–45. doi:10.​3122/​jabfm.​2011.​02.​100095.CrossRef
46.
go back to reference Hayes SM, Murray S, Castriotta RJ, et al. (Mis) perceptions and interactions of sleep specialists and generalists: obstacles to referrals to sleep specialists and the multidisciplinary team management of sleep disorders. J Clin Sleep Med. 2012;8(6):633–42. doi:10.5664/jcsm.2252.CrossRefPubMedPubMedCentral Hayes SM, Murray S, Castriotta RJ, et al. (Mis) perceptions and interactions of sleep specialists and generalists: obstacles to referrals to sleep specialists and the multidisciplinary team management of sleep disorders. J Clin Sleep Med. 2012;8(6):633–42. doi:10.​5664/​jcsm.​2252.CrossRefPubMedPubMedCentral
Metadata
Title
Screening Programs for Obstructive Sleep Apnea
Authors
Virginia S. de Los Reyes
Cecilia A. Jimeno
Vincent Anthony S. Tang
Patricia Marie M. Lusica
Publication date
01-06-2017
Publisher
Springer US
Published in
Current Pulmonology Reports / Issue 2/2017
Electronic ISSN: 2199-2428
DOI
https://doi.org/10.1007/s13665-017-0170-3

Other articles of this Issue 2/2017

Current Pulmonology Reports 2/2017 Go to the issue

Pulmonology in Combat Medicine (G Eapen, Section Editor)

Traumatic Brain Injury in Combat Trauma

Pulmonology in Combat Medicine (G Eapen, Section Editor)

Non-traumatic Pulmonary Emergencies in the Deployed Setting

Pulmonology in Combat Medicine (G Eapen, Section Editor)

Combat Venous Thromboembolism

Sleeping and Breathing (T Lee-Chiong, Section Editor)

Overlap Syndrome

Sleeping and Breathing (T Lee-Chiong)

Hypoventilation Syndromes

Sleeping and Breathing ( T Lee-Chiong, Section Editor)

Sleep-Related Breathing Disorders and Cancer

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine