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European Journal of Clinical Microbiology & Infectious Diseases
Published in: European Journal of Clinical Microbiology & Infectious Diseases 4/2003

01-04-2003 | Concise Article

Screening for Hepatitis B Virus DNA in Serum of Organ Donors and Renal Transplant Recipients

Authors: M. Miédougé, L. Rostaing, J. M. Mansuy, K. Sandres-Sauné, F. Boudet, J. Izopet

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 4/2003

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Abstract

In order to determine the impact of screening potential organ donors for hepatitis B virus DNA using a standardized test, the serum of 145 donor candidates was tested. All of the candidates were negative for hepatitis B virus DNA, but the status of one donor was doubtful for hepatitis B virus surface antigen and seven donors tested positive for hepatitis B virus core antibody without hepatitis B virus surface antigen. Nine transplant recipients tested positive for hepatitis B virus surface antibody; they were given kidneys from the donor with a doubtful hepatitis B virus surface antigen result and from four of the seven donors who tested positive for hepatitis B core antibody. Follow-up revealed no case of hepatitis B transmission. In this study, screening for hepatitis B virus DNA was useful and did not lead to donor organ shortage. Patients with hepatitis B virus surface antibodies can safely be given kidneys from donors who are positive for hepatitis B core antibody but negative for hepatitis B virus DNA.
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Metadata
Title
Screening for Hepatitis B Virus DNA in Serum of Organ Donors and Renal Transplant Recipients
Authors
M. Miédougé
L. Rostaing
J. M. Mansuy
K. Sandres-Sauné
F. Boudet
J. Izopet
Publication date
01-04-2003
Publisher
Springer-Verlag
Published in
European Journal of Clinical Microbiology & Infectious Diseases / Issue 4/2003
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-003-0889-3

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