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Published in: European Spine Journal 7/2015

01-07-2015 | Original Article

Scoliosis in patients with multiple hereditary exostoses

Authors: Yoshihiro Matsumoto, Kazu Matsumoto, Katsumi Harimaya, Seiji Okada, Toshio Doi, Yukihide Iwamoto

Published in: European Spine Journal | Issue 7/2015

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Abstract

Purpose

To investigate the prevalence of and to identify independent predictors associated with scoliosis in patients with multiple hereditary exostoses (MHE).

Methods

Fifty patients with MHE were clinically examined, and the diagnosis of scoliosis was made based on radiographs. To classify disease severity, three classes based on the presence of deformities and functional limitations were defined. Significant independent predictors of scoliosis in MHE were statistically analyzed.

Results

Scoliosis was present in 36 patients (MHE-scoliosis) (72 %). In the MHE-scoliosis group, the mean primary curve was 15.3° ± 5.7° (range 10°–34°) and the mean minor curve was 10.6° ± 7° (range 6°–32°). Left curve was predominant (72 %), and the apex was located in the thoracolumbar or lumbar spine in 64 % of patients. Univariable and multivariable analyses confirmed that MHE severity was a significant predictor of moderate scoliosis (≥20°).

Conclusions

Our study confirmed that scoliosis is a common feature of MHE and disease severity is a predictor of moderate scoliosis (≥20°).
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Metadata
Title
Scoliosis in patients with multiple hereditary exostoses
Authors
Yoshihiro Matsumoto
Kazu Matsumoto
Katsumi Harimaya
Seiji Okada
Toshio Doi
Yukihide Iwamoto
Publication date
01-07-2015
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 7/2015
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-015-3883-4

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