Scintigraphic outlook of patients and regions with myocardial necrosis at myocardial perfusion scintigraphy

Excerpt

Nudi et al. in their work entitled Assessment of the Fate of Myocardial Necrosis by Serial Myocardial Perfusion Imaging, 1 performed a retrospective analysis of SPECT (single-photon emission computed tomography) MPI (myocardial perfusion imaging) studies, where patients with repeat MPIs were included for indications other than acute coronary syndrome. Patients who underwent revascularization that was not performed in a setting of acute coronary syndrome were also included and further divided by LAD (left anterior descending coronary artery) and non-LAD perfusion territory revascularization. A novel necrosis score was used and the assigned score in each region was compared between the initial and repeat MPI study. MPI analysis was performed by assigning the highest degree of necrosis score to the patient. In the 3691 subjects, there were 25,837 segments, and 13% had necrosis. Only 48.9% of those with a clinical history of infarction had MPI evidence. Necrosis was highly reproducible on repeat MPI. There was no impact of either the site or type of revascularization in predicting necrosis on repeat MPI. …