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Published in: Infection 5/2023

Open Access 07-07-2023 | Schistosomiasis | Guideline

Schistosomiasis in non-endemic areas: Italian consensus recommendations for screening, diagnosis and management by the Italian Society of Tropical Medicine and Global Health (SIMET), endorsed by the Committee for the Study of Parasitology of the Italian Association of Clinical Microbiologists (CoSP-AMCLI), the Italian Society of Parasitology (SoIPa), the Italian Society of Gastroenterology and Digestive Endoscopy (SIGE), the Italian Society of Gynaecology and Obstetrics (SIGO), the Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV), the Italian Society of General Medicine and Primary Care (SIMG), the Italian Society of Infectious and Tropical Diseases (SIMIT), the Italian Society of Pediatrics (SIP), the Italian Society of Paediatric Infectious Diseases (SITIP), the Italian Society of Urology (SIU)

Authors: Agnese Comelli, Camilla Genovese, Federico Gobbi, Gaetano Brindicci, Susanna Capone, Angela Corpolongo, Verena Crosato, Valentina Dianora Mangano, Rosalia Marrone, Maria Merelli, Marco Prato, Carmen Rita Santoro, Salvatore Scarso, Elisa Vanino, Valentina Marchese, Spinello Antinori, Claudio Mastroianni, Annibale Raglio, Fabrizio Bruschi, Andrea Minervini, Daniele Donà, Silvia Garazzino, Luisa Galli, Andrea Lo Vecchio, Andrea Galli, Gabriele Dragoni, Claudio Cricelli, Nicola Colacurci, Enrico Ferrazzi, Annalisa Pieralli, Antonio Montresor, Joachim Richter, Guido Calleri, Alessandro Bartoloni, Lorenzo Zammarchi

Published in: Infection | Issue 5/2023

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Excerpt

Human schistosomiasis is a chronic parasitic disease caused by trematode worms of the genus Schistosoma. It affects people living in tropical and subtropical regions where approximately 780 million people are at risk[1]. …
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Literature
7.
go back to reference Brown BB. Delphi Process: A Methodology Used for the Elicitation of Opinions of Experts. Santa Monica, CA: RAND Corporation; 1968. Brown BB. Delphi Process: A Methodology Used for the Elicitation of Opinions of Experts. Santa Monica, CA: RAND Corporation; 1968.
19.
go back to reference Grandière-Pérez L, Ansart S, Paris L, Faussart A, Jaureguiberry S, Grivois J-P, et al. Efficacy of praziquantel during the incubation and invasive phase of Schistosoma haematobium schistosomiasis in 18 travelers. Am J Trop Med Hyg. 2006;74:814–8.CrossRefPubMed Grandière-Pérez L, Ansart S, Paris L, Faussart A, Jaureguiberry S, Grivois J-P, et al. Efficacy of praziquantel during the incubation and invasive phase of Schistosoma haematobium schistosomiasis in 18 travelers. Am J Trop Med Hyg. 2006;74:814–8.CrossRefPubMed
33.
go back to reference Granier H, Potard M, Diraison P, Nicolas X, Laborde JP, Talarmin F. Acute encephalitis concurrent with primary infection by schistosoma mansoni. Med Trop (Mars). 2003;63:60–3.PubMed Granier H, Potard M, Diraison P, Nicolas X, Laborde JP, Talarmin F. Acute encephalitis concurrent with primary infection by schistosoma mansoni. Med Trop (Mars). 2003;63:60–3.PubMed
43.
go back to reference Chaves NJ, Paxton GA, Biggs B, Thambiran A, Gardiner J, Williams J, et al. The Australasian Society for Infectious Diseases and Refugee Health Network of Australia recommendations for health assessment for people from refugee-like backgrounds: an abridged outline. Med J Aust. 2017;206:310–5. https://doi.org/10.5694/mja16.00826.CrossRefPubMed Chaves NJ, Paxton GA, Biggs B, Thambiran A, Gardiner J, Williams J, et al. The Australasian Society for Infectious Diseases and Refugee Health Network of Australia recommendations for health assessment for people from refugee-like backgrounds: an abridged outline. Med J Aust. 2017;206:310–5. https://​doi.​org/​10.​5694/​mja16.​00826.CrossRefPubMed
44.
go back to reference Istituto nazionale per la promozione della salute delle popolazioni migranti e per il contrasto delle malattie della povertà. I controlli alla frontiera. La frontiera dei controlli. Controlli sanitari all’arrivo e percorsi di tutela per i migranti ospiti 2017:1–116. www.inmp.it/lg/LG_Migranti-integrata.pdf Accessed 9 Mar, 2019. Istituto nazionale per la promozione della salute delle popolazioni migranti e per il contrasto delle malattie della povertà. I controlli alla frontiera. La frontiera dei controlli. Controlli sanitari all’arrivo e percorsi di tutela per i migranti ospiti 2017:1–116. www.​inmp.​it/​lg/​LG_​Migranti-integrata.​pdf Accessed 9 Mar, 2019.
46.
go back to reference National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Global Migration and Quarantine. Presumptive Treatment and Screening for Strongyloidiasis, Infections Caused by Other Soil-Transmitted Helminths, and Schistosomiasis among Newly Arrived Refugees 2019. https://stacks.cdc.gov/view/cdc/109513 Accessed 29 Jan 2023. National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Global Migration and Quarantine. Presumptive Treatment and Screening for Strongyloidiasis, Infections Caused by Other Soil-Transmitted Helminths, and Schistosomiasis among Newly Arrived Refugees 2019. https://​stacks.​cdc.​gov/​view/​cdc/​109513 Accessed 29 Jan 2023.
52.
go back to reference Bocanegra C, Álvarez-Martínez MJ, Arsuaga Vicente M, Belhassen-García M, Chamorro Tojeiro S, Camprubí-Ferrer D, et al. Executive summary consensus statement of imported diseases group (GEPI) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of tropical medicine and international health (setmsi), on the diagnostic and treatment of imported schistosomiasis. Enferm Infecc Microbiol Clin. 2023. https://doi.org/10.1016/j.eimc.2023.02.004.CrossRef Bocanegra C, Álvarez-Martínez MJ, Arsuaga Vicente M, Belhassen-García M, Chamorro Tojeiro S, Camprubí-Ferrer D, et al. Executive summary consensus statement of imported diseases group (GEPI) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of tropical medicine and international health (setmsi), on the diagnostic and treatment of imported schistosomiasis. Enferm Infecc Microbiol Clin. 2023. https://​doi.​org/​10.​1016/​j.​eimc.​2023.​02.​004.CrossRef
56.
go back to reference Abruzzi A, Fried B, Alikhan SB. Coinfection of Schistosoma Species with Hepatitis B or Hepatitis C Viruses. In: Rollinson D, Stothard JR, (eds). vol. 91, Academic Press; 2016. 111–231. Abruzzi A, Fried B, Alikhan SB. Coinfection of Schistosoma Species with Hepatitis B or Hepatitis C Viruses. In: Rollinson D, Stothard JR, (eds). vol. 91, Academic Press; 2016. 111–231.
60.
go back to reference Zammarchi L, Botta A, Tilli M, Gobbi F, Bartoloni A, Boccalini S. Presumptive treatment or serological screening for schistosomiasis in migrants from Sub-Saharan Africa could save both lives and money for the Italian National Health System: results of an economic evaluation. J Travel Med. 2022. https://doi.org/10.1093/jtm/taac140.CrossRefPubMed Zammarchi L, Botta A, Tilli M, Gobbi F, Bartoloni A, Boccalini S. Presumptive treatment or serological screening for schistosomiasis in migrants from Sub-Saharan Africa could save both lives and money for the Italian National Health System: results of an economic evaluation. J Travel Med. 2022. https://​doi.​org/​10.​1093/​jtm/​taac140.CrossRefPubMed
61.
go back to reference Beltrame A, Guerriero M, Angheben A, Gobbi F, Requena-Mendez A, Zammarchi L, et al. Accuracy of parasitological and immunological tests for the screening of human schistosomiasis in immigrants and refugees from African countries: an approach with latent class analysis. PLoS Negl Trop Dis. 2017;11:e0005593.CrossRefPubMedPubMedCentral Beltrame A, Guerriero M, Angheben A, Gobbi F, Requena-Mendez A, Zammarchi L, et al. Accuracy of parasitological and immunological tests for the screening of human schistosomiasis in immigrants and refugees from African countries: an approach with latent class analysis. PLoS Negl Trop Dis. 2017;11:e0005593.CrossRefPubMedPubMedCentral
63.
go back to reference Tamarozzi F, Ursini T, Hoekstra PT, Silva R, Costa C, Gobbi F, et al. Evaluation of microscopy, serology, circulating anodic antigen (CAA), and eosinophil counts for the follow-up of migrants with chronic schistosomiasis: a prospective cohort study. Parasit Vectors. 2021;14:1–11. https://doi.org/10.1186/s13071-021-04655-z.CrossRef Tamarozzi F, Ursini T, Hoekstra PT, Silva R, Costa C, Gobbi F, et al. Evaluation of microscopy, serology, circulating anodic antigen (CAA), and eosinophil counts for the follow-up of migrants with chronic schistosomiasis: a prospective cohort study. Parasit Vectors. 2021;14:1–11. https://​doi.​org/​10.​1186/​s13071-021-04655-z.CrossRef
71.
go back to reference IARC 1994 Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7–14 June 1994. Schistosomes, liver flukes and Helicobacter pylori. 61:1–241. IARC 1994 Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7–14 June 1994. Schistosomes, liver flukes and Helicobacter pylori. 61:1–241.
72.
go back to reference Colley DG, Bustinduy AL, Secor WE, King CH. Human schistosomiasis. The Lancet. 2014;383:2253–64.CrossRef Colley DG, Bustinduy AL, Secor WE, King CH. Human schistosomiasis. The Lancet. 2014;383:2253–64.CrossRef
81.
go back to reference Coltart CEM, Chew A, Storrar N, Armstrong M, Suff N, Morris L, et al. Schistosomiasis presenting in travellers: a 15 year observational study at the Hospital for Tropical Diseases, London. Trans R Soc Trop Med Hyg. 2015;109:214–20.CrossRefPubMed Coltart CEM, Chew A, Storrar N, Armstrong M, Suff N, Morris L, et al. Schistosomiasis presenting in travellers: a 15 year observational study at the Hospital for Tropical Diseases, London. Trans R Soc Trop Med Hyg. 2015;109:214–20.CrossRefPubMed
89.
go back to reference Barsoum IS, Colley DG, Kamal KA. Schistosoma mansoni: detection of circulating antigens in murine schistosomiasis by antigen-capture sandwich ELISA using a monoclonal antibody. Exper Parasitol. 1990;71:107.CrossRef Barsoum IS, Colley DG, Kamal KA. Schistosoma mansoni: detection of circulating antigens in murine schistosomiasis by antigen-capture sandwich ELISA using a monoclonal antibody. Exper Parasitol. 1990;71:107.CrossRef
99.
go back to reference Bierman WFW, Wetsteyn JCFM, Gool T. Presentation and diagnosis of imported schistosomiasis: relevance of eosinophilia, microscopy for ova, and serology. J Travel Med. 2006;12:9–13.CrossRef Bierman WFW, Wetsteyn JCFM, Gool T. Presentation and diagnosis of imported schistosomiasis: relevance of eosinophilia, microscopy for ova, and serology. J Travel Med. 2006;12:9–13.CrossRef
104.
go back to reference Richter J, Hatz C, Campagne G, Bergquist NR, Jenkins JM, for Research UBSP, et al. 1996 Ultrasound in schistosomiasis : a practical guide to the standard use of ultrasonography for assessment of schistosomiasis-related morbidity : Second international workshop, Niamey, Niger Richter J, Hatz C, Campagne G, Bergquist NR, Jenkins JM, for Research UBSP, et al. 1996 Ultrasound in schistosomiasis : a practical guide to the standard use of ultrasonography for assessment of schistosomiasis-related morbidity : Second international workshop, Niamey, Niger
108.
go back to reference Marangoni D. Diagnosi e gestione clinica della schistosomiasi urogenitale complicata: revisione sistematica della letteratura. Univer Flor. 2021;11:455. Marangoni D. Diagnosi e gestione clinica della schistosomiasi urogenitale complicata: revisione sistematica della letteratura. Univer Flor. 2021;11:455.
112.
go back to reference OMS. 2015 Female genital schistosomiasis: A pocket atlas for clinical health-care professionals. Who/Htm/Ntd/20154. 2015:49. OMS. 2015 Female genital schistosomiasis: A pocket atlas for clinical health-care professionals. Who/Htm/Ntd/20154. 2015:49.
120.
go back to reference WHO Expert Committee on the Control of Schistosomiasis. Prevention and control of schistosomiasis and soil-transmitted helminthiasis: report of a WHO expert committee. World Health Organization 2001. WHO Expert Committee on the Control of Schistosomiasis. Prevention and control of schistosomiasis and soil-transmitted helminthiasis: report of a WHO expert committee. World Health Organization 2001.
122.
go back to reference Zwang J, Olliaro PL. Clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis—a meta-analysis of comparative and non-comparative clinical trials. PLoS Negl Trop Dis. 2014;8:e3286.CrossRefPubMedPubMedCentral Zwang J, Olliaro PL. Clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis—a meta-analysis of comparative and non-comparative clinical trials. PLoS Negl Trop Dis. 2014;8:e3286.CrossRefPubMedPubMedCentral
128.
129.
go back to reference Burchard G, Ehrhardt S, Grobusch M, Junghanss T, Löscher T, Reisinger E, et al. Leitlinie: diagnostik und therapie der schistosomiasis (Bilharziose). AWMF Online Das Portal Der Wissenschaftlichen Medizin. 2013;42:1–36. Burchard G, Ehrhardt S, Grobusch M, Junghanss T, Löscher T, Reisinger E, et al. Leitlinie: diagnostik und therapie der schistosomiasis (Bilharziose). AWMF Online Das Portal Der Wissenschaftlichen Medizin. 2013;42:1–36.
130.
133.
go back to reference World Health Organization. Strategy Development and Monitoring for Parasitic Diseases and Vector Control Team. (2003). Report of the WHO informal consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months: Geneva, 8–9 April 2002. World Health Organization. World Health Organization. Strategy Development and Monitoring for Parasitic Diseases and Vector Control Team. (2003). Report of the WHO informal consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months: Geneva, 8–9 April 2002. World Health Organization.
136.
go back to reference N’Goran EK, Yalkinoglu Ö, Kourany-Lefoll E, Tappert A, Hayward B, Yin X, et al. Efficacy and safety of new orodispersible tablet formulations of praziquantel (racemate and l-praziquantel) in schistosoma mansoni-infected preschool-age children and infants: a randomized dose-finding phase 2 study. Front Trop Dis. 2021. https://doi.org/10.3389/fitd.2021.679373.CrossRef N’Goran EK, Yalkinoglu Ö, Kourany-Lefoll E, Tappert A, Hayward B, Yin X, et al. Efficacy and safety of new orodispersible tablet formulations of praziquantel (racemate and l-praziquantel) in schistosoma mansoni-infected preschool-age children and infants: a randomized dose-finding phase 2 study. Front Trop Dis. 2021. https://​doi.​org/​10.​3389/​fitd.​2021.​679373.CrossRef
150.
152.
go back to reference Whitty CJM, Mabey DC, Armstrong M, Wright SG, Chiodini PL. Presentation and outcome of 1107 cases of schistosomiasisfrom Africa diagnosed in a non-endemic country. Trans R Soc Trop Med Hyg. 2000;94:531–4.CrossRefPubMed Whitty CJM, Mabey DC, Armstrong M, Wright SG, Chiodini PL. Presentation and outcome of 1107 cases of schistosomiasisfrom Africa diagnosed in a non-endemic country. Trans R Soc Trop Med Hyg. 2000;94:531–4.CrossRefPubMed
153.
go back to reference Yong MK, Beckett CL, Leder K, Biggs BA, Torresi J, O’Brien DP. Long-term follow-up of schistosomiasis serology post-treatment in Australian Travelers and Immigrants. J Travel Med. 2010;17:89–93.CrossRefPubMed Yong MK, Beckett CL, Leder K, Biggs BA, Torresi J, O’Brien DP. Long-term follow-up of schistosomiasis serology post-treatment in Australian Travelers and Immigrants. J Travel Med. 2010;17:89–93.CrossRefPubMed
158.
go back to reference Barda B, Coulibaly JT, Hatz C, Keiser J. Ultrasonographic evaluation of urinary tract morbidity in school-aged and preschool-aged children infected with Schistosoma haematobium and its evolution after praziquantel treatment: A randomized controlled trial. PLoS Negl Trop Dis. 2017;11:1–13. https://doi.org/10.1371/journal.pntd.0005400.CrossRef Barda B, Coulibaly JT, Hatz C, Keiser J. Ultrasonographic evaluation of urinary tract morbidity in school-aged and preschool-aged children infected with Schistosoma haematobium and its evolution after praziquantel treatment: A randomized controlled trial. PLoS Negl Trop Dis. 2017;11:1–13. https://​doi.​org/​10.​1371/​journal.​pntd.​0005400.CrossRef
160.
go back to reference Akpata R, Neumayr A, Holtfreter MC, Krantz I, Singh DD, Mota R, et al. The WHO ultrasonography protocol for assessing morbidity due to Schistosoma haematobium. Acceptance and evolution over 14 years. Syst rev Parasitol Res. 2015;114:1279–89.CrossRef Akpata R, Neumayr A, Holtfreter MC, Krantz I, Singh DD, Mota R, et al. The WHO ultrasonography protocol for assessing morbidity due to Schistosoma haematobium. Acceptance and evolution over 14 years. Syst rev Parasitol Res. 2015;114:1279–89.CrossRef
Metadata
Title
Schistosomiasis in non-endemic areas: Italian consensus recommendations for screening, diagnosis and management by the Italian Society of Tropical Medicine and Global Health (SIMET), endorsed by the Committee for the Study of Parasitology of the Italian Association of Clinical Microbiologists (CoSP-AMCLI), the Italian Society of Parasitology (SoIPa), the Italian Society of Gastroenterology and Digestive Endoscopy (SIGE), the Italian Society of Gynaecology and Obstetrics (SIGO), the Italian Society of
Authors
Agnese Comelli
Camilla Genovese
Federico Gobbi
Gaetano Brindicci
Susanna Capone
Angela Corpolongo
Verena Crosato
Valentina Dianora Mangano
Rosalia Marrone
Maria Merelli
Marco Prato
Carmen Rita Santoro
Salvatore Scarso
Elisa Vanino
Valentina Marchese
Spinello Antinori
Claudio Mastroianni
Annibale Raglio
Fabrizio Bruschi
Andrea Minervini
Daniele Donà
Silvia Garazzino
Luisa Galli
Andrea Lo Vecchio
Andrea Galli
Gabriele Dragoni
Claudio Cricelli
Nicola Colacurci
Enrico Ferrazzi
Annalisa Pieralli
Antonio Montresor
Joachim Richter
Guido Calleri
Alessandro Bartoloni
Lorenzo Zammarchi
Publication date
07-07-2023
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 5/2023
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-023-02050-7

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