Skip to main content
Top
Published in: Current Obesity Reports 1/2016

01-03-2016 | Psychological Issues (M Hetherington and V Drapeau, Section Editors)

Satiety Innovations: Food Products to Assist Consumers with Weight Loss, Evidence on the Role of Satiety in Healthy Eating: Overview and In Vitro Approximation

Authors: Rubén López-Nicolás, Massimo Marzorati, Lia Scarabottolo, Jason C. G. Halford, Alexandra M. Johnstone, Carmen Frontela-Saseta, Angel M. Sanmartín, Gaspar Ros-Berruezo, Joanne A. Harrold

Published in: Current Obesity Reports | Issue 1/2016

Login to get access

Abstract

The prevalence of overweight and obesity is increasing globally, driven by the availability of energy-dense palatable foods. Most dietary strategies fail because of hunger generated by calorie restriction, and interventions that specifically control hunger and/or promote fullness may aid success. Current consumers have a limited choice of satiety-enhancing products with proven health benefits, and innovative ways to produce new foods (as structural modification) to enhance satiety/satiation may provide new opportunities. However, this potential is hindered by the cost of product testing. Within the SATIN—SATiety INnovation project—an in vitro platform has been developed to offer a cost-effective means of assessing the potential satiation/satiety effect of novel foods. This combines in vitro technologies to assess changes in colonic bacteria metabolism, appetite hormone release and the stability and bioavailability of active compounds in the new products/ingredients. This article provides a brief review of nutrients for which an impact on short-term appetite regulation has been demonstrated, and a summary of the changes to food structure which can be used to produce a change in appetite expression. Furthermore, the SATIN in vitro platform is discussed as a means of assessing the impact of nutritional and structural manipulations on appetite.
Literature
1.
go back to reference Cani PD, Delzenne NM. The role of the gut microbiota in energy metabolism and metabolic disease. Curr Pharm Des. 2009;15(13):1546–58.CrossRefPubMed Cani PD, Delzenne NM. The role of the gut microbiota in energy metabolism and metabolic disease. Curr Pharm Des. 2009;15(13):1546–58.CrossRefPubMed
2.
go back to reference Kalm LM, Semba RD. They starved so that others be better fed: remembering Ancel keys and the Minnesota experiment. J Nutr. 2005;135:1347–52.PubMed Kalm LM, Semba RD. They starved so that others be better fed: remembering Ancel keys and the Minnesota experiment. J Nutr. 2005;135:1347–52.PubMed
3.
go back to reference Stubbs J, Pallister C, Avery A, et al. Weight, body mass index and behaviour change in a commercially run lifestyle programme for young people. J Hum Nutr Diet. 2012;25(2):161–6.CrossRefPubMed Stubbs J, Pallister C, Avery A, et al. Weight, body mass index and behaviour change in a commercially run lifestyle programme for young people. J Hum Nutr Diet. 2012;25(2):161–6.CrossRefPubMed
4.
go back to reference Halford JCG, Harrold JA. Satiety-enhancing products for appetite control: science and regulation of functional foods for weight management. Proc Nutr Soc. 2012;71:350–62.CrossRefPubMed Halford JCG, Harrold JA. Satiety-enhancing products for appetite control: science and regulation of functional foods for weight management. Proc Nutr Soc. 2012;71:350–62.CrossRefPubMed
6.
go back to reference Van Kleef E, Van Trijp JCM, Van Den Borne JJGC, Zondervan C. Successful development of satiety enhancing food products: towards a multidisciplinary agenda of research challenges. Crit Rev Food Sci Nutr. 2012;52(7):611–28.CrossRefPubMedPubMedCentral Van Kleef E, Van Trijp JCM, Van Den Borne JJGC, Zondervan C. Successful development of satiety enhancing food products: towards a multidisciplinary agenda of research challenges. Crit Rev Food Sci Nutr. 2012;52(7):611–28.CrossRefPubMedPubMedCentral
7.
8.
go back to reference Johnstone AM. Safety and efficacy of high-protein diets for weight loss. Proc Nutr Soc. 2012;71(2):339–49.CrossRefPubMed Johnstone AM. Safety and efficacy of high-protein diets for weight loss. Proc Nutr Soc. 2012;71(2):339–49.CrossRefPubMed
9.
go back to reference Westerterp-Plantenga MS, Rolland V, Wilson SAJ, et al. Satiety related to 24 h diet-induced thermogenesis during high protein carbohydrate vs high fat diets measured in a respiration chamber. Eur J Clin Nutr. 1999;53(6):495–502.CrossRefPubMed Westerterp-Plantenga MS, Rolland V, Wilson SAJ, et al. Satiety related to 24 h diet-induced thermogenesis during high protein carbohydrate vs high fat diets measured in a respiration chamber. Eur J Clin Nutr. 1999;53(6):495–502.CrossRefPubMed
10.
go back to reference Skov AR, Toubro S, Ronn B, et al. Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity. Int J Obes. 1999;23(5):528–36.CrossRef Skov AR, Toubro S, Ronn B, et al. Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity. Int J Obes. 1999;23(5):528–36.CrossRef
11.
go back to reference Larsen TM, Dalskov S-M, van Baak M, et al. Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med. 2010;363(22):2102–13.CrossRefPubMedPubMedCentral Larsen TM, Dalskov S-M, van Baak M, et al. Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med. 2010;363(22):2102–13.CrossRefPubMedPubMedCentral
12.
go back to reference Eisenstein J, Roberts SB, Dallai G, et al. High-protein weight-loss diets: are they safe and do they work? A review of the experimental and epidemiological data. Nutr Rev. 2002;60:189–200.CrossRefPubMed Eisenstein J, Roberts SB, Dallai G, et al. High-protein weight-loss diets: are they safe and do they work? A review of the experimental and epidemiological data. Nutr Rev. 2002;60:189–200.CrossRefPubMed
13.
go back to reference Westerterp-Plantenga MS, Lejeune MP. Protein intake and body weight regulation. Appetite. 2005;45:187–90.CrossRefPubMed Westerterp-Plantenga MS, Lejeune MP. Protein intake and body weight regulation. Appetite. 2005;45:187–90.CrossRefPubMed
14.
go back to reference Pesta DH, Samuel VT. A high-protein diet for reducing body fat: mechanisms and possible caveats. Nutr Metab. 2014;11:53.CrossRef Pesta DH, Samuel VT. A high-protein diet for reducing body fat: mechanisms and possible caveats. Nutr Metab. 2014;11:53.CrossRef
15.
go back to reference Veldhorst MA, Nieuwenhuizen AG, Hochstenbach-Waelen A, et al. Dose-dependent satiating effect of whey relative to casein or soy. Physiol Behav. 2009;96(4–5):675–82.CrossRefPubMed Veldhorst MA, Nieuwenhuizen AG, Hochstenbach-Waelen A, et al. Dose-dependent satiating effect of whey relative to casein or soy. Physiol Behav. 2009;96(4–5):675–82.CrossRefPubMed
16.
go back to reference Gilbert JA, BEnden NT, Tremblay A, et al. Effects of proteins from different sources on body composition. Nutr Metab Cardiovasc Dis. 2011;21:B16–31.CrossRefPubMed Gilbert JA, BEnden NT, Tremblay A, et al. Effects of proteins from different sources on body composition. Nutr Metab Cardiovasc Dis. 2011;21:B16–31.CrossRefPubMed
17.
go back to reference Wanders AJ, van den Born JJGC, de Graaf C, et al. Effect of dietary fibre on subjective appetite, energy intake and body weight: a systematic review of randomised controlled trials. Obes Rev. 2011;12:724–39.PubMed Wanders AJ, van den Born JJGC, de Graaf C, et al. Effect of dietary fibre on subjective appetite, energy intake and body weight: a systematic review of randomised controlled trials. Obes Rev. 2011;12:724–39.PubMed
18.
go back to reference Astrup A, Vrist E, Quaade F. Dietary fibre added to very low calorie diet reduced hunger and alleviates constipation. Int J Obes. 1990;14(2):105–12.PubMed Astrup A, Vrist E, Quaade F. Dietary fibre added to very low calorie diet reduced hunger and alleviates constipation. Int J Obes. 1990;14(2):105–12.PubMed
19.
go back to reference Rigaud D, Ryttig KR, Leeds AR, et al. Effects of a moderate dietary fibre supplement on hunger rating, energy input and faecal energy output in young, healthy volunteers. A randomized, double-blind cross-over trial. Int J Obes. 1987;1:73–8. Rigaud D, Ryttig KR, Leeds AR, et al. Effects of a moderate dietary fibre supplement on hunger rating, energy input and faecal energy output in young, healthy volunteers. A randomized, double-blind cross-over trial. Int J Obes. 1987;1:73–8.
20.
go back to reference Aston LM, Stokes CS, Jebb SA. No effect of a diet with a reduced glycemic index on satiety, energy intake and body weight in overweight and obese women. Int J Obes. 2008;32(1):160–5.CrossRef Aston LM, Stokes CS, Jebb SA. No effect of a diet with a reduced glycemic index on satiety, energy intake and body weight in overweight and obese women. Int J Obes. 2008;32(1):160–5.CrossRef
21.
go back to reference Burton-Freeman B. Dietary fiber and energy regulation. J Nutr. 2000;130(2):2725–55. Burton-Freeman B. Dietary fiber and energy regulation. J Nutr. 2000;130(2):2725–55.
22.
go back to reference Dikeman CL, Fahey GC. Viscosity as related to dietary fibre: a review. Crit Rev Food Sci Nutr. 2006;46(8):649–63.CrossRefPubMed Dikeman CL, Fahey GC. Viscosity as related to dietary fibre: a review. Crit Rev Food Sci Nutr. 2006;46(8):649–63.CrossRefPubMed
23.
go back to reference Vuksan V, Panahi S, Lyon M, et al. Viscosity of fiber preloads affects food intake in adolescents. Nutr Metab Cardiovasc Dis. 2009;19:498–503.CrossRefPubMed Vuksan V, Panahi S, Lyon M, et al. Viscosity of fiber preloads affects food intake in adolescents. Nutr Metab Cardiovasc Dis. 2009;19:498–503.CrossRefPubMed
24.
go back to reference Howarth NC, Saltzman E, Roberts SB. Dietary fiber and weight regulation. Nutr Rev. 2001;59(5):129–39.CrossRefPubMed Howarth NC, Saltzman E, Roberts SB. Dietary fiber and weight regulation. Nutr Rev. 2001;59(5):129–39.CrossRefPubMed
25.
go back to reference Hoad CL, Rayment P, Spiller RC, et al. In vivo imaging of intragastric gelation and its effect on satiety in humans. J Nutr. 2001;134:2293–300. Hoad CL, Rayment P, Spiller RC, et al. In vivo imaging of intragastric gelation and its effect on satiety in humans. J Nutr. 2001;134:2293–300.
26.
go back to reference Behall KM, Scholfield DJ, Hallfrisch JG, et al. Consumption of both resistant starch and beta-glucan improves postprandial plasma glucose and insulin in women. Diabetes Care. 2006;29:976–81.CrossRefPubMed Behall KM, Scholfield DJ, Hallfrisch JG, et al. Consumption of both resistant starch and beta-glucan improves postprandial plasma glucose and insulin in women. Diabetes Care. 2006;29:976–81.CrossRefPubMed
27.
go back to reference Casiraghi MC, Garsetti M, Testolin G, et al. Post-prandial responses to cereal products enriched with barley beta-glucan. J Am Coll Nutr. 2006;25(4):313–20.CrossRefPubMed Casiraghi MC, Garsetti M, Testolin G, et al. Post-prandial responses to cereal products enriched with barley beta-glucan. J Am Coll Nutr. 2006;25(4):313–20.CrossRefPubMed
28.
go back to reference Raben A, Tagliabue A, Christensen NJ, et al. Resistant starch: the effect on postprandial glycemia, hormonal response and satiety. Am J Clin Nutr. 1994;60(4):544–51.PubMed Raben A, Tagliabue A, Christensen NJ, et al. Resistant starch: the effect on postprandial glycemia, hormonal response and satiety. Am J Clin Nutr. 1994;60(4):544–51.PubMed
29.
go back to reference de Roos N, Heijnen ML, de Graaf C, et al. Resistant starch has little effect on appetite, food intake and insulin secretion in healthy young men. Eur J Clin Nutr. 1995;49(7):532–41.PubMed de Roos N, Heijnen ML, de Graaf C, et al. Resistant starch has little effect on appetite, food intake and insulin secretion in healthy young men. Eur J Clin Nutr. 1995;49(7):532–41.PubMed
30.
go back to reference Nilsson AC, Ostman EM, Holst JJ, et al. Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast. J Nutr. 2008;138:732–9.PubMed Nilsson AC, Ostman EM, Holst JJ, et al. Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast. J Nutr. 2008;138:732–9.PubMed
32.
go back to reference Di Meglio D, Matts RD. Liquid versus solid carbohydrates: effects on food intake and body weight. Int J Obes. 2000;24:794–800.CrossRef Di Meglio D, Matts RD. Liquid versus solid carbohydrates: effects on food intake and body weight. Int J Obes. 2000;24:794–800.CrossRef
33.
go back to reference Almiron-Roig E, Chen Y, Drewnowski A. No difference in satiety or in subsequent energy intakes between a beverage and a solid food. Physiol Behav. 2004;82:671–7.CrossRefPubMed Almiron-Roig E, Chen Y, Drewnowski A. No difference in satiety or in subsequent energy intakes between a beverage and a solid food. Physiol Behav. 2004;82:671–7.CrossRefPubMed
34.
go back to reference Kristensen M, Jensen MG. Dietary fibres in the regulation of appetite and food intake. Importance of viscosity. Appetite. 2011;56:65–70.CrossRefPubMed Kristensen M, Jensen MG. Dietary fibres in the regulation of appetite and food intake. Importance of viscosity. Appetite. 2011;56:65–70.CrossRefPubMed
35.
go back to reference Wolf BW, Lai CS, Kipnes MS, et al. Glycemic and insulinemic responses of non-diabetic healthy adult subjects to an experimental acid-induced viscosity complex incorporated into a glucose beverage. Nutrition. 2002;18:621–6.CrossRefPubMed Wolf BW, Lai CS, Kipnes MS, et al. Glycemic and insulinemic responses of non-diabetic healthy adult subjects to an experimental acid-induced viscosity complex incorporated into a glucose beverage. Nutrition. 2002;18:621–6.CrossRefPubMed
36.
go back to reference Turnbaugh PJ, Ridaura VK, Faith JJ, et al. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med. 2009;1(6). Turnbaugh PJ, Ridaura VK, Faith JJ, et al. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med. 2009;1(6).
38.
go back to reference Zhou J, Martin RJ, Tulley RT, et al. Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents. Am J Physiol Endocrinol Metab. 2008;295(5):E1160–6.CrossRefPubMedPubMedCentral Zhou J, Martin RJ, Tulley RT, et al. Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents. Am J Physiol Endocrinol Metab. 2008;295(5):E1160–6.CrossRefPubMedPubMedCentral
39.
go back to reference Backhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A. 2004;101(44):15718–23.CrossRefPubMedPubMedCentral Backhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A. 2004;101(44):15718–23.CrossRefPubMedPubMedCentral
40.
go back to reference Possemiers S, Grootaert C, Vermeiren J, et al. The intestinal environment in health and disease—recent insights on the potential of intestinal bacteria to influence human health. Curr Pharm Des. 2009;15(18):2051–65.CrossRefPubMed Possemiers S, Grootaert C, Vermeiren J, et al. The intestinal environment in health and disease—recent insights on the potential of intestinal bacteria to influence human health. Curr Pharm Des. 2009;15(18):2051–65.CrossRefPubMed
41.
go back to reference de Wiele TV, Boon N, Possemiers S, et al. Prebiotic effects of chicory inulin in the simulator of the human intestinal microbial ecosystem. FEMS Microbiol Ecol. 2004;51(1):143–53.CrossRefPubMed de Wiele TV, Boon N, Possemiers S, et al. Prebiotic effects of chicory inulin in the simulator of the human intestinal microbial ecosystem. FEMS Microbiol Ecol. 2004;51(1):143–53.CrossRefPubMed
42.
go back to reference Terpend K, Possemiers S, Daguet D, et al. Arabinogalactan and fructo-oligosaccharides have a different fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®). Environ Microbiol Rep. 2013;5(4):595–603.CrossRefPubMed Terpend K, Possemiers S, Daguet D, et al. Arabinogalactan and fructo-oligosaccharides have a different fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®). Environ Microbiol Rep. 2013;5(4):595–603.CrossRefPubMed
43.
go back to reference Marzorati M, Possemiers S, Verhelst A, et al. A novel hypromellose capsule, with acid resistance properties, permits the targeted delivery of acid-sensitive products to the intestine. LWT Food Sci Technol. 2015;60(1):544–51.CrossRef Marzorati M, Possemiers S, Verhelst A, et al. A novel hypromellose capsule, with acid resistance properties, permits the targeted delivery of acid-sensitive products to the intestine. LWT Food Sci Technol. 2015;60(1):544–51.CrossRef
44.
go back to reference Sanchez JI, Marzorati M, Grootaert C, et al. Arabinoxylan-oligosaccharides (AXOS) affect the protein/carbohydrate fermentation balance and microbial population dynamics of the Simulator of Human Intestinal Microbial Ecosystem. Microb Biotechnol. 2009;2(1):101–13.CrossRefPubMedPubMedCentral Sanchez JI, Marzorati M, Grootaert C, et al. Arabinoxylan-oligosaccharides (AXOS) affect the protein/carbohydrate fermentation balance and microbial population dynamics of the Simulator of Human Intestinal Microbial Ecosystem. Microb Biotechnol. 2009;2(1):101–13.CrossRefPubMedPubMedCentral
45.•
go back to reference Van den Abbeele P, Roos S, Eeckhaut V, et al. Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli. Microb Biotechnol. 2012;5(1):106–15. This study provides a thorough description of the maximum degree of complexity a gut simulator can reach with the incorporation of a luminal and mucosal compartment in each colon sector.CrossRefPubMedPubMedCentral Van den Abbeele P, Roos S, Eeckhaut V, et al. Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli. Microb Biotechnol. 2012;5(1):106–15. This study provides a thorough description of the maximum degree of complexity a gut simulator can reach with the incorporation of a luminal and mucosal compartment in each colon sector.CrossRefPubMedPubMedCentral
46.
go back to reference Janssen S, Depoortere I. Nutrient sensing in the gut: new roads to therapeutics? Trends Endocrinol Metab. 2013;24(2):92–100.CrossRefPubMed Janssen S, Depoortere I. Nutrient sensing in the gut: new roads to therapeutics? Trends Endocrinol Metab. 2013;24(2):92–100.CrossRefPubMed
48.
go back to reference Neary MT, Batterham RL. Gut hormones: implications for the treatment of obesity. Pharmacol Ther. 2009;124(1):44–56.CrossRefPubMed Neary MT, Batterham RL. Gut hormones: implications for the treatment of obesity. Pharmacol Ther. 2009;124(1):44–56.CrossRefPubMed
49.
go back to reference Nguyen CA, Akiba Y, Kaunitz JD. Recent advances in gut nutrient chemosensing. Curr Med Chem. 2012;19(1):28–34.CrossRefPubMed Nguyen CA, Akiba Y, Kaunitz JD. Recent advances in gut nutrient chemosensing. Curr Med Chem. 2012;19(1):28–34.CrossRefPubMed
50.•
go back to reference Le Neve B, Daniel H. Selected tetrapeptides lead to a GLP-1 release from the human enteroendocrine cell line NCI-H716. Regul Pept. 2011;167(1):14–20. This study demonstrates the potential to use the human NCI-H716 cells as a valid in vitro model to study the induction of GLP-1 secretion upon the application of different stimuli. CrossRefPubMed Le Neve B, Daniel H. Selected tetrapeptides lead to a GLP-1 release from the human enteroendocrine cell line NCI-H716. Regul Pept. 2011;167(1):14–20. This study demonstrates the potential to use the human NCI-H716 cells as a valid in vitro model to study the induction of GLP-1 secretion upon the application of different stimuli. CrossRefPubMed
51.
go back to reference Kim K, Lee YM, Rhyu M-R, et al. Spergularia marina induces glucagon-like peptide-1 secretion in NCI-H716 cells through bile acid receptor activation. J Med Food. 2014;17(11):1197–203.CrossRefPubMedPubMedCentral Kim K, Lee YM, Rhyu M-R, et al. Spergularia marina induces glucagon-like peptide-1 secretion in NCI-H716 cells through bile acid receptor activation. J Med Food. 2014;17(11):1197–203.CrossRefPubMedPubMedCentral
52.
go back to reference Hira T, Maekawa T, Asano K, et al. Cholecystokinin secretion induced by beta-conglycinin peptone depends on G alpha q-mediated pathways in enteroendocrine cells. Eur J Nutr. 2009;48(2):124–7.CrossRefPubMed Hira T, Maekawa T, Asano K, et al. Cholecystokinin secretion induced by beta-conglycinin peptone depends on G alpha q-mediated pathways in enteroendocrine cells. Eur J Nutr. 2009;48(2):124–7.CrossRefPubMed
53.
go back to reference O'Sullivan L, Ryan L, Aherne SA, et al. Cellular transport of lutein is greater from uncooked rather than cooked spinach irrespective of whether it is fresh, frozen, or canned. Nutr Res. 2008;28(8):532–8.CrossRefPubMed O'Sullivan L, Ryan L, Aherne SA, et al. Cellular transport of lutein is greater from uncooked rather than cooked spinach irrespective of whether it is fresh, frozen, or canned. Nutr Res. 2008;28(8):532–8.CrossRefPubMed
54.
go back to reference Laparra JM, Glahn RP, Miller DD. Assessing potential effects of inulin and probiotic bacteria on Fe availability from common beans (Phaseolus vulgaris L.) to Caco-2 cells. J Food Sci. 2009;74(2):H40–6.CrossRefPubMed Laparra JM, Glahn RP, Miller DD. Assessing potential effects of inulin and probiotic bacteria on Fe availability from common beans (Phaseolus vulgaris L.) to Caco-2 cells. J Food Sci. 2009;74(2):H40–6.CrossRefPubMed
55.
go back to reference Loennerdal B. Soybean ferritin: implications for iron status of vegetarians. Am J Clin Nutr. 2009;89(5):S1680–5.CrossRef Loennerdal B. Soybean ferritin: implications for iron status of vegetarians. Am J Clin Nutr. 2009;89(5):S1680–5.CrossRef
Metadata
Title
Satiety Innovations: Food Products to Assist Consumers with Weight Loss, Evidence on the Role of Satiety in Healthy Eating: Overview and In Vitro Approximation
Authors
Rubén López-Nicolás
Massimo Marzorati
Lia Scarabottolo
Jason C. G. Halford
Alexandra M. Johnstone
Carmen Frontela-Saseta
Angel M. Sanmartín
Gaspar Ros-Berruezo
Joanne A. Harrold
Publication date
01-03-2016
Publisher
Springer US
Published in
Current Obesity Reports / Issue 1/2016
Electronic ISSN: 2162-4968
DOI
https://doi.org/10.1007/s13679-016-0196-9

Other articles of this Issue 1/2016

Current Obesity Reports 1/2016 Go to the issue

Etiology of Obesity (T Gill, Section Editor)

The Link Between Inadequate Sleep and Obesity in Young Adults

Psychological Issues (M Hetherington and V Drapeau, Section Editors)

Restaurant Menu Labeling Policy: Review of Evidence and Controversies

Etiology of Obesity (T Gill, Section Editor)

Weight-Related Dietary Behaviors in Young Adults

Etiology of Obesity (T Gill, Section Editor)

The Health Consequences of Obesity in Young Adulthood

Psychological Issues (M Hetherington and V Drapeau, Section Editors)

Obesity Prevention Programs in Children: Impact on Weight, Shape and Food Concern

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine