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01-12-2021 | SARS-CoV-2 | Review

Kawasaki disease recurrence in the COVID-19 era: a systematic review of the literature

Authors: Alice Annalisa Medaglia, Lucia Siracusa, Claudia Gioè, Salvatore Giordano, Antonio Cascio, Claudia Colomba

Published in: Italian Journal of Pediatrics | Issue 1/2021

Abstract

Kawasaki disease (KD) is a vasculitis of unknown origin of small and medium caliber blood vessels, especially involving coronary arteries and is the leading cause of acquired heart disease in childhood in developed countries. Although rarely, it can recur: most recurrences occur within 2 years of the initial episode. No data are available on incidence of recurrent KD in Europe and multiple recurrences are rarely seen. We reviewed the medical literature on Kawasaki disease recurrence and reported a new case of Kawasaki disease recurrence in a child with SARS-CoV-2 infection. We believe that in our case SARS Cov2 acted as a trigger capable to determine, in a genetically susceptible individual, a second recurrence of the disease. In the Covid-19 era we affirm the importance for Kawasaki disease to be tested for SARS Cov2 infection.

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Title: Kawasaki disease recurrence in the COVID-19 era: a systematic review of the literature
Authors: Alice Annalisa Medaglia
Lucia Siracusa
Claudia Gioè
Salvatore Giordano
Antonio Cascio
Claudia Colomba
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: SARS-CoV-2
COVID-19
Kawasaki Disease
Kawasaki Disease
Kawasaki Disease
Published in: Italian Journal of Pediatrics / Issue 1/2021
Electronic ISSN: 1824-7288
DOI: https://doi.org/10.1186/s13052-021-01041-4

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Kawasaki disease recurrence in the COVID-19 era: a systematic review of the literature

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