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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | SARS-CoV-2 | Research Letter

Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study

Authors: Megan Fraissé, Elsa Logre, Olivier Pajot, Hervé Mentec, Gaëtan Plantefève, Damien Contou

Published in: Critical Care | Issue 1/2020

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Excerpt

Patients admitted to the intensive care unit (ICU) for coronavirus disease 2019 (COVID-19), following an infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seem to have an increased risk of thrombotic events (TE), both arterial and venous [1‐3]. Even in the absence of high level of evidence, some centers have consequently modified their pharmacological thromboprophylaxis strategy toward intermediate or full-dose (therapeutic) preemptive anticoagulation (rather than prophylactic dosing) for routine care of COVID-19 patients [2, 4], exposing them to a higher risk of hemorrhagic events (HE). …
Literature
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Cui S, Chen S, Li X, Liu S, Wang F. Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia. J Thromb Haemost JTH. 2020.
2.
Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Gommers D A. MPJ, Kant KM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020;.
3.
Helms J, Tacquard C, Severac F, Leonard-Lorant I, Ohana M, Delabranche X, et al. High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med. 2020.
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Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P, et al. Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology. 2020;200432.
Metadata
Title
Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study
Authors
Megan Fraissé
Elsa Logre
Olivier Pajot
Hervé Mentec
Gaëtan Plantefève
Damien Contou
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03025-y

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